Jonathan Lawrence Email and Phone Number
Jonathan Lawrence work email
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Jonathan Lawrence personal email
I am a motivated and impactful research and development scientist. I have expertise in medicinal and synthetic chemistry, translating candidates from discovery into the clinic, and developing and executing clinical programs. I've led discovery projects, clinical development programs, individuals and departments, and influenced the scientific and strategic direction of companies -- across multiple therapeutic modalities. I am well-versed in building discovery platforms, assessing a program's scientific, commercial and clinical feasibility, and managing a company-wide portfolio. I am highly proficient at being able to tackle the small details as well as the big picture simultaneously. I keenly focus on the professional development of my reports, and actively craft a culture of innovation and collaboration for entire organizations. I have extensive experience and success in winning non-dilutive and dilutive funding awards. I have thrived in both established (>1000 employees) and start-up (<20 employees) biotech environments.
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Vice President, Discovery ChemistryJudo Bio Jun 2022 - PresentCambridge, Ma, Us
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Executive Director And Head Of ChemistryKaleido Biosciences Feb 2022 - Apr 2022Lexington, Massachusetts, UsKey responsibility includes leading the expansion of Kaleido's Discovery Platform, in order to identifify and translate the next-generation of clinical candidates for use in immune and inflammatory diseases. -
Senior Director, Head Of ChemistryKaleido Biosciences Jan 2021 - Jan 2022Lexington, Massachusetts, Us● Led strategic pivot of KB109 Program from COVID-19 indication to acute exacerbations of COPD (AE-COPD), including collaboration with the COPD Foundation to pursue a Phase 2 study● As Head of Chemistry Department and member of the Discovery Leadership Team, responsible for budget, short and long-range strategy, and developing the next generation of leaders within the team● Key driver to establish a Long Range Plan for Research, including the refinment of Kaleido's core technology platform
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DirectorKaleido Biosciences Feb 2020 - Jan 2021Lexington, Massachusetts, Us● Created and led the COVID-19 Program, including the nomination of KB109, and the design, execution, and data read-outs of three human clinical studies of 350+ patients with mild/moderate COVID-19.● Presented COVID-19 Program to regulatory authorities including MHRA, Sweden, Germany, and The Netherlands.● Led interactions with BARDA CoronaWatch and TechWatch meeting process, seeking non-dilutive funding for Kaeido's infectious disease portfolio● Continued leadership of Infectious Disease Development Program, including strategic collaboration with MD Anderson Cancer Center for the exploration of pre-clinical animal models in gut barrier damage, chemo- and radiation therapy
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Associate DirectorKaleido Biosciences Oct 2017 - Feb 2020Lexington, Massachusetts, Us● Group leader for a team of medicinal chemists. Co-Inventor of multiple Development Candidates, including KB174, KB109, and KB867.● Scientific Lead for Pathogen Discovery Team and identified, nominated, and tech-transfered Development Candidate KB109. Assumed Program Leader role for KB109 Program to design, execute, and read-out First-in-Human Study.● Scientific Lead for KB174 Clinical Development Program in Hepatic Encephalopathy. Supported execution and read-out of multiple clinical studies.● Project leader for cross-functional discovery teams working across diverse therapeutic areas including Chemotherapy-Induced Toxicity, Infection Prevention, and rare metabolic disorders (Propionic Acidemia/Methylmalonic Acidemia). ● Led establishment of a robust patent estate around lead chemical matter, in collaboration with in-house IP legal team.● Primary author and presenter for a CARB-X funding application, resulting in a conditionally-accepted proposal.
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DirectorMacrolide Pharmaceuticals (Now Eloxx Pharmaceuticals) May 2016 - Oct 2017● Continued leadership role to bring proprietary macrolide candidates through IND-enabling studies and report progress to Board of Directors and Scientific Advisory Board.● Inventor of company's lead candidates. Lead author for company's successful CARB-X award.● Managed a group of internal scientists as well as external CRO chemists.
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Associate DirectorMacrolide Pharmaceuticals (Now Eloxx Pharmaceuticals) May 2015 - May 2016● Responsible for start-up and build-out of six-person Discovery Chemistry Department, including physical lab space and equipment. Successfully completed technology transfer from Harvard University.● Provided quarterly updates directly to both Scientific Advisory Board and Board of Directors.● Developed and implemented company's chemistry plan that successfully discovered proprietary macrolides active against historically "untouchable" multidrug-resistant Gram-negative bacteria.
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Senior Scientist I, Discovery ChemistryCubist Pharmaceuticals Dec 2014 - May 2015Lexington, Ma, Us -
Scientist Ii, Discovery ChemistryCubist Pharmaceuticals Feb 2012 - May 2015Lexington, Ma, Us● Led Hit-to-Lead and Lead-Optimization stage antibacterial drug discovery projects, which involved leading highly cross-functional teams with membership from chemistry, biology, computational chemistry and biology, pharmacology, and non-clinical development. ● Managed the strategy and workflow of 13-16 synthetic and medicinal chemists.
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Scientist I, Discovery ChemistryCubist Pharmaceuticals Jul 2008 - Feb 2012Lexington, Ma, Us● Contributed to a multitude of projects across antibacterial and pain therapeutic areas. ● Managed a small group of junior chemists.● Functioned as synthetic chemistry go-to resource for the department. ● Project Leader for multiple exploratory-stage projects, one of which nominated and advanced CB-618 to Phase I clinical trials.
Jonathan Lawrence Skills
Jonathan Lawrence Education Details
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Harvard UniversityOrganic Chemistry -
University Of RochesterMusic
Frequently Asked Questions about Jonathan Lawrence
What company does Jonathan Lawrence work for?
Jonathan Lawrence works for Judo Bio
What is Jonathan Lawrence's role at the current company?
Jonathan Lawrence's current role is Vice President of Discovery Chemistry at Judo Bio.
What is Jonathan Lawrence's email address?
Jonathan Lawrence's email address is jo****@****ido.com
What schools did Jonathan Lawrence attend?
Jonathan Lawrence attended Harvard University, University Of Rochester.
What skills is Jonathan Lawrence known for?
Jonathan Lawrence has skills like Drug Discovery, Organic Synthesis, Chemistry, Medicinal Chemistry, Organic Chemistry, Drug Design, Pharmaceutical Industry, Hplc, Nmr, Synthetic Organic Chemistry, Chromatography, Purification.
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