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Research track faculty in the HIVE group and lead for the High-performance Integrated Virtual Environment (HIVE) bioinformatics platform at The George Washington University, the BioCompute project, and several others, including AI/ML pilot projects.Co-PI, Co-I, or lead for several projects with small, interdisciplinary teams. Primary responsibilities are leading research and development teams and writing proposals and publications, but additional responsibilities in teaching, mentorship, and departmental service.Experience building collaborative, multi-disciplinary teams, proposal writing, and championing projects through publications and talks. Areas of technical subject matter include data analysis, bioinformatics workflows, open source standards, data curation, and developmental neuro-genomics (especially copy number variation (CNV)). More recently, I have also contributed to infectious disease projects, including influenza and HIV. Details about two of the flagship projects are below.-------------------------------------------------------------------------------------------------------------------BioComputeBioCompute is a descriptive standard (officially IEEE-2791-2020) for recording computational workflows, and is the only framework to have ever by adopted by the FDA's Data Standards Catalog. It is accepted for four types of drug applications at three Centers, and has been used in formal submissions to the FDA for regulatory clearance. As the Secretary of the P2791 Working Group, I was a driving force in assembling and operating the group, and was a key figure in bringing the project to the attention of the FDA's Data Standards Board for Guidance publication. I have trained both pharma and FDA personnel in its use. I also initiated a public private partnership between CBER at the FDA and our University.https://www.biocomputeobject.org/HIVEThe High-performance Integrated Virtual Environment (HIVE) is a powerful bioinformatics platform originally developed at the FDA that is particularly strong with noisy, real world data. Our institution maintains several instances of the platform for use in several projects with highly sensitive data. As the lead for the project, I deploy new instances of the platform, write and test new workflows, carry out database administration and general server maintenance, and have general oversight of the platform and several of the projects that make use of it. Many of these projects involve work in the private sector and do not result in publications.https://hive.biochemistry.gwu.edu/dna.cgi?cmd=main
George Washington Univeristy
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Assistant Professor, Research TrackGeorge Washington Univeristy May 2019 - PresentBioinformatics, Department of Biochemistry & Molecular Medicine -
Member, Executive Steering CommitteeBiocompute Nov 2018 - Present
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PrincipalQuandary Studio Jan 2015 - PresentAs part of the Quandary Group, Quandary Studio helped commercialize emerging tech. Our role in the group was to produce data visualization, data graphics, technical illustrations, concept renderings, animations, virtual reality, and other forms of media, providing clear, articulate understandings of highly technical content.• Initiated partnership to become exclusive provider of data graphics, visualizations, and academic illustrations for a national science writing company• Built training scenario for Chicago's United Center with full recreation of the structure• Proposed novel projects in the research and medical space• Initiated and maintained client relationships to sustain and grow business• Proposed, lead team to semi-finals for National Institute of Standards and Technology challenge• Discovered and developed partnerships with technical talent, managed team• Initiated collaborations, partnerships, and other professional relationships
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Senior Program Manager, R&DThe George Washington University School Of Medicine And Health Sciences Apr 2018 - May 2019Foggy BottomBioCompute is a collaborative initiative between George Washington University and the FDA to generate a standards protocol for all next gen sequencing workflow data. The standards are meant to increase reproducibility, be adaptable, improve the pipeline through FDA regulatory evaluations, and be able to interface with any digital platform in order to minimize disruption to existing workflow.We expect most users to fall into three categories: 1. Researchers who want to improve reproducibility, 2. clinical settings (precision medicine and genetic tests) that have a strong need to accurately communicate health information that includes NGS data, and 3. pharmaceutical and biotech companies who submit work to the FDA for regulatory review. We happily welcome input from every corner of the community that analyzes any manner of high throughput sequencing data, or otherwise carries out bioinformatic analyses pipelines. If you have thoughts or feedback that you'd like to share, please reach out to me directly!BioCompute is maturing beyond grant funding and into a Public-Private Partnership. We're currently exploring revenue models that will satisfy all end users. Our goal is to keep the standards open, but to make BioCompute a self-sustaining venture. If you're interested in contributing to this discussion, please contact me.
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Director Of Complex VisualizationTrans1 Jun 2015 - Aug 2017Denver• Proposed, budgeted, managed and produced a virtual reality spine surgery simulation; presented at North American Spine Society annual meeting• Worked with legal team to develop novel public private partnerships• Initiated collaborations with technical talent• Developed 3D viewer model library for sales team• Interfaced with Research & Development Team and executive leadership• Research existing Medicaid policy, propose action strategy• Propose, design, and generate physician and patient-facing collateral -
Technical SpecialistRocky Mountain Patent May 2014 - Jun 20151514 Blake St. Denver, Co 80202• Provide expertise and assist with neuroscience, genomics, medical device, and general life science technology-related matter for clients• Researched existing prior art technology• Draft specifications and claims for patents• Provided research and insight into specific emerging technologies -
Postdoctoral ResearcherUniversity Of Colorado Health Sciences Center Apr 2014 - Jul 2014• Proposed and executed novel research, including novel transgenic mouse line and neural stem cell lines• Identified and initiated multiple partnerships, including high profile hospital partnership to analyze human fetal brain tissue• Developed novel big data (RNAseq) experiment and analysis, requiring Perl, Linux and R• Represented the lab in many presentations• Contributed to several grants and publications• Built and seeded Genetitree -- the genetics counterpart to Neurotree -
Professional Research AssistantUniversity Of Colorado At Boulder Apr 2007 - Jun 2008 -
Learning AssistantUniversity Of Colorado Boulder Aug 2007 - Dec 2007Boulder, CoLead two recitation sections of undergraduates in Introduction to Molecular, Cellular and Developmental Biology. My teaching used a novel teaching strategy that focused almost exclusively on high level concepts, and did not spend time discussing or reviewing homework. Rather than reiterating standalone concepts, the strategy was more concerned with the ways in which the concepts interrelate in a broader context, thus providing a more comprehensive picture. These two groups scored the highest in the class. -
Lab TechnicianCytogenetics Specialists, Inc. Aug 2006 - Mar 2007Primarily FISH and molecular techniques for diagnosis and prognosis of blood-borne cancers. CLSp(MB) certification, HER2neu pathology certification. -
Undergraduate Teaching AssistantUniversity Of Colorado Boulder Aug 2002 - Dec 2002Boulder, CoLead two undergraduate wetlabs in Introduction to Molecular, Cellular and Developmental Biology.
Jonathon Keeney, Ph.D. Skills
Jonathon Keeney, Ph.D. Education Details
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Neuroscience -
Molecular, Cellular And Developmental Biology
Frequently Asked Questions about Jonathon Keeney, Ph.D.
What company does Jonathon Keeney, Ph.D. work for?
Jonathon Keeney, Ph.D. works for George Washington Univeristy
What is Jonathon Keeney, Ph.D.'s role at the current company?
Jonathon Keeney, Ph.D.'s current role is Assistant Professor, Research Track.
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What schools did Jonathon Keeney, Ph.D. attend?
Jonathon Keeney, Ph.D. attended University Of Colorado Anschutz Medical Campus, University Of Colorado Boulder.
What are some of Jonathon Keeney, Ph.D.'s interests?
Jonathon Keeney, Ph.D. has interest in Mind/brain Problem, Electronics, Neural Interface, Human Intelligence, Personalized Genomics, Virtual Reality, Science Fiction, Comparative Primate And Paleogenomics, Data Visualization, Human Origins.
What skills is Jonathon Keeney, Ph.D. known for?
Jonathon Keeney, Ph.D. has skills like Fluorescence Microscopy, Immunohistochemistry, Molecular Biology, Perl, Python, R, 3d Visualization, Genomics, Virtual Reality, Molecular Cloning, Laboratory, Pcr.
Who are Jonathon Keeney, Ph.D.'s colleagues?
Jonathon Keeney, Ph.D.'s colleagues are Kurt Johnson, 王小花, George Brittle, Vudata Rao, Mikyong Kim, George Bozzini, David Fede.
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