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Highly adaptable organic chemist experienced in working cross functionally within multi-disciplined teams to deliver synthetic solutions to challenges at the intersections of organic synthesis, photocatalysis, biocatalysis, and analytical chemistry. Enjoys learning and incorporating new chemistries and technology (software and automation) to increase efficiency in achieving project goals.Summary of Skills and Experience Analytical• Skilled with all major purification and analytical platforms (HPLC/SFC/GC, NMR, IR, and MS) utilizing Chemstation, Masslynx, Reaction Analytics iChem, Virscidian Analytical Studio, and Excel for data management and analysis.• Experienced in acquisition, management, and analysis of large LC/SFC/MS high-throughput experimentation datasets. Biology/Biochemistry• Experienced with common biochemical techniques including gel electrophoresis, cell-based protein expression, and protein purification. Optimization and performance of in vitro assays for IC50 determinations. Experienced in handling and storage of enzymes both purified and cell free lysate.Chemical Synthesis• In-depth knowledge of synthetic organic chemistry with experience in heterocycle synthesis, biocatalysis, photocatalysis, diversity-oriented synthesis, and scale up (analytical micro to hundreds of grams).• Experienced in high-throughput experimentation (HTE) and analysis (HTA) in an industry setting. Computational and Software• Proficient with a range of in silico modeling software for small molecule – protein interactions, virtual screening, and visualizations including PyRx, Pymol, VMD, NAMD, AutoDock Vina, UCSF Chimera, and MOE.• Skilled in the use of a range of software including the Microsoft Suite (Teams, Excel, Word, OneNote, PowerPoint, SharePoint), and TIBCO Spotfire.Industrial• 3 years in an industry setting working in pharmaceutical discovery and development. Performed workflow planning/execution, led cross-discipline project meetings, and managed project milestones in a highly collaborative environment
Synovai Inc
View- Website:
- pfizer.com
- Employees:
- 112906
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Chief Scientific OfficerSynovai IncEast Lansing, Mi, Us -
Postdoctoral ResearcherPfizer Jan 2022 - PresentGroton, Connecticut, United States -
Postdoctoral Research AssociateUniversity Of Wisconsin-Madison Jul 2019 - Oct 2021• Utilized interdisciplinary background to bridge the two groups’ specialties improving communication while clarifying and realigning project short- and long-term goals resulting in two publications. • Identified failings/omissions in literature casting doubt on project viability. Subsequently designed and synthesized simplified macromolecular compound as a viability test which was active and resulted in project continuation.• Identified limitations in the current chemical space and, thorough collaboration, identified targets outside the original scope. Subsequently synthesized desired compounds.• Supported a collaborators alternative solution by synthesizing the required photo-responsive maleimide-azo-quaternary ammonia diazo benzene. -
Laboratory Saftey OfficerMichigan State University May 2017 - May 2019Collaborate with Environmental Health and Saftey (EHS) to maintain health and safety regulations.Developed and implemented standard operation procedures (SOPs) in accordance with EHS regulation.Perform on site training to new and visiting researchers. -
Graduate Research AssistantMichigan State University Aug 2013 - May 2019Adviser: Dr. Jetze TepeResearch: My research is based around proteasome manipulation. Utilizing computer modeling, I design and synthesize small molecule heterocycles as both enhancers and inhibitors of the human proteasome for use in neurological disorders and anti neoplastic activity respectively.Additionally, I explore and develop novel methodologies for the swift construction of small molecule heterocycles. In the course of this research I have:• Solved a 7 year group “paradox” by inventing an unprecedented theoretical framework for small molecule activation of the human proteasome. Also provided the first data for predicting and explaining small molecule effects on proteasome regulation in support of this framework. Results aided in securing NIH funding of ~$1,000,000 annually for the lab. Acknowledged on the group news feed January 10th, 2020.• Designed, synthesized, and tested >50 heterocyclic compounds for proteasome modulation.• Successfully modified existing commercial phenothiazine antipsychotic to the first rationally designed proteasome activity enhancer with no detectable binding of original target. • Developed new lab standard procedures in utilizing computational methods for designing proteasome modulators, and assay evaluation of synthesized compounds. • Originated 3 different projects to current multi-investigator programs in the group.• Developed the first reported, and first rationally designed, direct human proteasome activator, opening a novel area for therapeutic intervention in a host of neurodegenerative diseases. -
Graduate Teaching AssistantMichigan State University Aug 2013 - May 2019Independently prepared and lead 50 min recitations each weekIndependently guided 8-24 students in organic laboratories 6-8 hours each weekGraded exams, quizzes, lab reports, and provided feedback to students. -
Lecturer Organic Chemistry IiMichigan State University Jul 2018 - Aug 2018Farmington HillsFull lecturer for second semester Organic Chemistry in the Summer II section. -
Undergraduate Teaching AssistantUniversity Of Tennessee At Martin Aug 2011 - May 2013-As a teaching assistant I worked with multiple professors in teaching first year general chemistry laboratories.-Worked for the Chemistry Department Stock Room in preparing chemicals and instruments for use in lab-Held weekly Office Hours, Graded Lab reports and Homework, Led two help sessions per week -Led an additional two hour help session for sophomore level Organic Chemistry (Fall 2012- Spring 2013) -
Research AssistantUniversity Of Tennessee At Martin Aug 2010 - May 2013MartinUndergraduate Research:Adviser: Dr. Mark KeranenResearch: Investigation into cascade hydroformylation reactions of electron deficient nitroalkenes for the one-pot synthesis of beta-lactams. Synthesis of various nitroalkene starting materials through the Henry ReactionAnalyzed and optimized hydroformylation procedures to yield a novel functional group inter-conversion. -
Teaching AssistantBrookhaven National Laboratory Jun 2012 - Jul 2012Aiding in Nuclear Chemistry Summer School Program (NCSS) funded by DOE in setting up labs, teaching proper instrumentation use, laboratory technique, and radiological safety.
Corey Jones Skills
Corey Jones Education Details
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Organic Chemistry -
Chemistry
Frequently Asked Questions about Corey Jones
What company does Corey Jones work for?
Corey Jones works for Synovai Inc
What is Corey Jones's role at the current company?
Corey Jones's current role is Chief Scientific Officer.
What is Corey Jones's email address?
Corey Jones's email address is cj****@****isc.edu
What is Corey Jones's direct phone number?
Corey Jones's direct phone number is +193162*****
What schools did Corey Jones attend?
Corey Jones attended Michigan State University, University Of Tennessee At Martin.
What skills is Corey Jones known for?
Corey Jones has skills like Microsoft Office, Uv/vis Spectroscopy, Organic Chemistry, Teaching, Microsoft Excel, Data Analysis, Nuclear Magnetic Resonance, Microsoft Powerpoint, High Performance Liquid Chromatography, Small Molecule Docking, Molecular Dynamics, Heterocyclic Chemistry.
Who are Corey Jones's colleagues?
Corey Jones's colleagues are Jennifer Mougeotte, Mba, Pmp, Rym Kadiri, Oscar Enrique Ponce Ornelas, Barbara Beccaris, Emily Williams, D.ha, Mha, Cce, Dan Durst, Xudong Ye.
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