Jordi Petriz Email & Phone Number

The ability to bridge large-scale and single cell approaches at a functional level are key to identify biomarkers expressed in rare cells, and particularly in cancer stem cells (CSCs). We are an interdisciplinary group that investigates and develops key experimental approaches to understand the principles underlying the emergence and prevention of tumorigenesis and cancer therapy resistance, with the aim to translate biomedical science into integrated clinical practice and public health with certified transference processes in cooperation with trusted allies and partners.Cancer is a complex group of diseases with serious implications not just for individuals and their families, but also for society in general and health a system in particular, remains an important health challenge. Patients can respond differently to the same medicine, and many patients do not benefit from the first drug they are offered in treatment. The patient’s condition can change dramatically in a short period of time due to treatment and illness. Complications developed by these patients are known to have better outcomes with earlier identification and management, and collaboration between different supporting disciplines is of great importance.Given that current clinical application of functional cytomics remains largely confined to few specific academic centers, our goal is to provide the patients with a wide range of scientific support strategies, through precision, oversight and accuracy.Since more than three decades we study the implications of multidrug resistance transporters in stem and cancer cell biology. The CSC model has been established as a cellular mechanism that contributes to phenotypic and functional heterogeneity in diverse cancer types. Recent observations, however, have highlighted many complexities and challenges: the CSC phenotype can vary substantially between patients, tumors may harbor multiple phenotypically or genetically distinct CSCs, metastatic CSCs can evolve from primary CSCs, and tumor cells may undergo reversible phenotypic changes.

Listed skills include Flow Cytometry, Immunostaining, Facs, In Situ Hybridization, and 45 others.

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  Universitat De Barcelona

  Physiology And Immunology, General