Automating evidence based medicine using EHR data to improve patient care

Ideated, developed, tested, and deployed software in Python and Javascript to identify patients at risk of hereditary cancer based on patient family history information and clinical practice guidelinesDeveloped OWL ontology and description logic formalisms for hereditary cancer clinical practice guidelines to automate referral recommendationsConducted ad campaigns resulting in over 5,000 family histories collected and analyzed for hereditary cancer riskDesigned and implemented an API to generate clinician and patient facing reports with family pedigree visualizations and cancer family history informationCoordinated efforts across cross-functional teams to deploy the full software product for family history collection and hereditary cancer-risk assessmentConducted product research and participated in forming strategy to achieve product-market fit through extensive analysis of the voice of the customer

Developed roadmap for leading therapeutic assets through to clinical trialsWorked closely with stakeholders and scientific research team to create go to market strategy and raise capital Gathered and synthesized market research, clinical trial data, and data collected from interviews with experts to refine product-market fitPitched to ~100 life science investors at virtual Demo Day event sponsored by the Notre Dame IDEA center and Purdue UniversityImplemented lean startup methodology and processes

Maintained legacy Java applications responsible for organizing patient data and generating patient facing reports Updated and supported Java application for reading microarray sequencing dataWorked as a member of a multi-team effort to release stable product updates

Owned and lead product-wide testing and bug resolution for flagship product resulting in zero downtime and no major bugs in productionOwned the agenda for and ran weekly stakeholder meetings to facilitate cross-team insights and recommendations for leadership teamManaged team of engineers in India responsible for gathering and synthesizing genomic knowledge base to generate actionable insights on patient dataMaintained and deployed new versions of the genomic knowledge base Developed and maintained testing framework in Java and oversaw continuous integration effortsDeveloped selenium testing framework in Python to automate bug discovery Developed tools in Python to help parse information from VCF filesContributed development to APIs using OMIM and ClinVar APIs

Dr. Steven Johnson's lab studies chromatin architecture in C. elegans. Specifically Dr. Johnson studies nucleosome positioning as a means of manipulating the DNA sequence to regulate gene expression. Ultimately Dr. Johnson's research aims to discover epigenetic mechanisms by which genes can be regulated in order to improve human healthWhile in his lab I was awarded an ORCA grant that enabled me to complete a program written in java that recovers nucleosomes from restriction enzyme digested C. elegans DNA samples. The program is multi-threaded and leverages several third party programs including Bowtie and SAMtools. Manuscript is in prep.While in his lab I also performed histone octamer reconstitutions preparatory to analyzing sequence specific DNA histone interactions. I also assisted in running DNA and Protein gels, extracting and purifying DNA from worms, and other lab assignments.

The Senior Missionary Training Center is responsible for aiding all Senior missionaries preparing to serve missions in foreign countries to learn the language they will be speaking. I taught Thai to many elderly missionary couples who would serve in Thailand and assisted many other couples who would serve in various other countries. They would go on to serve in roles such as welfare, finance, publicity, and many other capacities for the Church in their respective countries. One of the couples I had the opportunity to tutor was President and Sister David Senior. They were called to oversee all church work in Thailand, Laos, and Myanmar. I also had the privilege to teach several General Officers of the Mormon church ESL. The department assigned me to oversee and develop a new Thai grammar guide, which upon completion was over 100 pages. I was recruited by the guided language program where I worked with a team of tutors, language specialists, and volunteers to promote more effective language learning. We developed a program that enabled tutors to teach missionaries how to learn language that the tutors themselves did not speak.