José Pires Email & Phone Number
Who is José Pires? Overview
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José Pires is listed as Marie Curie PhD Fellow at University of Copenhagen (Københavns Universitet), a with 333 employees, based in Felgueiras, Porto, Portugal. AeroLeads shows a matched LinkedIn profile for José Pires.
José Pires previously worked as Master Student at I3S - Instituto De Investigação E Inovação Em Saúde and Research Trainee at I3S - Instituto De Investigação E Inovação Em Saúde. José Pires holds Phd Cellular & Genetic Medicine, Biology/Biological Sciences, General from University Of Copenhagen (Københavns Universitet).
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About José Pires
I'm José Pires, having recently completed my Biochemistry (BSc) and Medicine and Molecular Oncology (MSc) degrees at the University of Porto. Previously, my research at i3s delved into the intricate realm of gastric cancer extracellular vesicles glycosylation, with a specialized emphasis on truncated O-glycans. Now, transitioning to a new chapter, I am thrilled to embark on my doctoral journey at the University of Copenhagen, under the guidance of Hans Wandall. Over the upcoming three years, I will be dedicated to unraveling the complexities of carbohydrate structures within the gastrointestinal tract. This endeavor is part of the esteemed TOPGUT Marie Curie network, where I eagerly anticipate contributing and expanding my expertise in molecular oncology research
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José Pires work experience
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Marie Curie Phd Fellow
Will be conducting research and pursuing my doctoral studies at University of Copenhagen (Københavns Universitet) under Hans Wandall's mentorship. Over the next three years, I'll focus on characterizing carbohydrate complexity in the gastrointestinal tract. Part of TOPGUT Marie Curie network.
Master Student
In my master's thesis project, I focused on gastric cancer, a highly lethal form of cancer with a significant global health impact. This type of cancer is often diagnosed at advanced stages and is usually asymptomatic until then, making effective treatment challenging. My research centered on abnormal glycosylation patterns, specifically the presence of a specific truncated O-glycan called sialyl-Tn (STn), which is associated with poor prognosis and tumor aggressiveness in gastric cancer. I investigated how cancer-derived extracellular vesicles (EVs) enriched in STn can influence the behavior of recipient gastric cancer cells, shedding light on their role in cancer progression. For that I took advantage of functional in vitro assays and RT-qPCR analysis. This research opened doors for further exploration of the underlying molecular mechanisms, involved in EV horizontal programming processes.
Research Trainee
This internship was a part of my First Degree in Biochemistry, in which the presence of STn both in cells and EVs of a glycoengineered cell line (MKN45 Simple-Cell), that highly expresses STn, was studied. EVs characterization was performed through western blot and their concentration and integrity though, respectively, nanoparticle tracking analysis (NTA) and transmission electron microscopy (TEM). Imuno-gold labelling TEM was performed on the EVs released by this cell line, in order to detect the presence of STn on its membrane. STn presence was also studied on gastric cancer patients tissues, through immunohistochemistry assays. All these techniques helped me to understand a little better the whole world of investigation in cancer.
José Pires education
Phd Cellular & Genetic Medicine, Biology/Biological Sciences, General
Master'S Degree, Medicine And Molecular Oncology, 18
Bachelor'S Degree, Biochemistry, 16
Frequently asked questions about José Pires
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What company does José Pires work for?
José Pires works for University of Copenhagen (Københavns Universitet).
What is José Pires's role at University of Copenhagen (Københavns Universitet)?
José Pires is listed as Marie Curie PhD Fellow at University of Copenhagen (Københavns Universitet).
Where is José Pires based?
José Pires is based in Felgueiras, Porto, Portugal while working with University of Copenhagen (Københavns Universitet).
What companies has José Pires worked for?
José Pires has worked for University Of Copenhagen (Københavns Universitet) and I3S - Instituto De Investigação E Inovação Em Saúde.
How can I contact José Pires?
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What schools did José Pires attend?
José Pires holds Phd Cellular & Genetic Medicine, Biology/Biological Sciences, General from University Of Copenhagen (Københavns Universitet).
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