Vice President, head of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) at Merck Research Labs

DMPKDepartment of Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics (PDMB)

DMPK South Francisco and Boston

Group leader for Discovery and Preclinical Development support of protein therapeutics, small molecules, and additional therapeutic modalities. - Manage PK/PD/ADME support of Discovery and Preclinical Development portfolio across multiple therapeutic areas (Inflammation, Oncology, Immuno-oncology, and Cardio Metabolic) and therapeutic modalities. - PKDM project team representative on Discovery and Preclinical Development protein therapeutic programs in Inflammation, Oncology, and Immuno-oncology). - Direct management of PKDM project team representatives and laboratory group leaders. - Oversight of matrix environment laboratory activities for multiple subgroups (cellular and protein interaction, large molecule ADME, nonGLP bioanalytical, etc.). - Due diligence for in-licensing opportunities. - Scientific partner for Amgen Ventures; member of Scientific Advisory Board

PK and molecular ADME support for discovery and preclinical development of protein therapeutics in inflammation, immune modulation, and immuno-oncology. - Manage PK/PD/ADME support of Discovery and Preclinical Development portfolio across multiple therapeutic areas (Inflammation, Oncology, & Immuno-oncology) and therapeutic modalities. - PKDM project team representative on Discovery and Preclinical Development protein therapeutic programs in Inflammation, Oncology, and Immuno-oncology). - Direct management of PKDM project team representatives and laboratory personnel. - Due diligence for in-licensing opportunities.

PK, ADME, and molecular interaction support of small molecule and protein therapeutic discovery programs in Inflammation and immune modulation. - PKDM project team representative on Discovery small molecule and protein therapeutic programs in Inflammation and Oncology. - Direct management of laboratory personnel. - Laboratory responsibilities included IND enabling ADME studies for Preclinical Development programs and biophysical and enzymology support of Discovery programs.

PK, ADME, and molecular interaction support of small molecule and protein therapeutic discovery programs in Inflammation and immune modulation. - PKDM project team representative on Discovery small molecule programs in Inflammation and Oncology. - Laboratory responsibilities included IND enabling ADME studies for Preclinical Development programs and biophysical and enzymology support of Discovery programs.

Biophysical characterization of protein and protein/ligand dynamics under the supervision of William M. Atkins, Ph.D.

Research: Micro-channel chemical reactors for the production of hydrocarbon fuels on MarsResearch Director: Dr. Darby Makel