*Manage project activities for ambulatory operations to improve patient care, experience, and access to services

• Served as Community Outreach and Engagement liaison to UVA Comprehensive Cancer Center’s research programs and translational teams creating bridges for scientists and community• Promoted collaborations and fostered health equity in programs to best provide community research support• Managed community-engaged research projects and evaluation of initiatives• Scientific and administrative support for research proposals, grant writing, budgets, and manuscripts

• Program Manager for AACR Project Genomics Evidence Neoplasia Information Exchange (Project GENIE), a clinical and genomic registry developed to advance precision medicine and improved outcomes for patients with cancer• Managed development of an Immuno-Oncology portal to house clinical and genomic data from clinical trials • Managed sponsored research projects • Worked closely with Sage Bionetworks team and cBioPortal team at Memorial Sloan Kettering Cancer Center for data management, provenance, and processing

• Founding director of the Oncology Research Information Exchange Network (ORIEN) program at UVA, program manager for national consortium participation• Developed workflows bridging clinical and research operations• Built infrastructure by developing partnerships with clinical teams for consenting, specimen collections and specimen processing to support Partners in Discovery clinical trial• Continuous process improvement during development of workflows that hinged on standard of care procedures and root cause analyses as part of corrective action plans for protocol deviations • Collaborated with informatics developer to design and implement a database with alerts to achieve 100% monitoring of Epic and OnCore documentation • Managed IT infrastructure for documentation monitoring for compliance, clinical data abstractions, specimen tracking and molecular data storage• During this tenure: over 7,500 patients were consented, over 550 paired tumor/germline samples were sequenced, collection of over 3,000 blood samples, over 3,000 buccal swabs and over 400 bone marrow aspirates• Managed research coordinator staffing and workflows in ambulatory clinics and inpatient units• Coordinated internal research project development and external research collaborations• Served on ORIEN Scientific Committee; Data and Tissue Acquisition, Quality and Access Committee and Biospecimen Taskforce• Managed team of clinical research coordinators and data abstractors• Managed large scale sequencing project• Managed data abstractions for national projects (AVATAR and Apollo 5) and pharmaceutical sponsored chart review studies• Scientific liaison for development of cancer data mart• Mentor undergraduate interns in partnership with UVA Internship Placement Program

• Managed and successfully completed initial accreditation for National Accreditation Program for Breast Center (NAPBC) accreditations for the Cancer Center• Maintained Commission on Cancer (CoC) and National Accreditation Program for Breast Center (NAPBC) accreditations• Developed low dose CT lung cancer screening program and patient education in collaboration with radiology department• Managed Tumor Board case requests and led weekly meetings• Managed Cancer Registry in compliance with CoC and NAACCR standards and developed quality reports• Managed Cancer Committee and led meetings for monitoring of programmatic activities• Coordinated Quality Oncology Practice Initiative (QOPI) participation• Performed quality improvement studies • Managed community outreach events and cancer screenings• Managed IRB review and documentation for hospital trials and trials of affiliated physicians• Supervised clinical research nurse, nurse navigators and certified tumor registrars

• Reviewed all IRB submissions with high level of detail• Maintained regulatory binders for all hospital clinical trials and improved organizational efficiency• Completed successful FDA audit• Completed successful cooperative group affiliate member audit• Maintain policies, procedures and IRB member education with periodic updates

• Comprehensive literature reviews and technical editing• Scientific liaison for database development team

Ph.D. Dissertation: Mitotic regulation of p190RhoGap • Breast cancer research laboratory of Dr. Sarah Parsons• Developed and performed experiments to study the regulation of a tumor suppressor protein and its impact on the actin cytoskeleton and mitosis in affecting cell growth• Publicationso Haskell MD, Nickles AL, Agati JM, Su L, Dukes BD, Parsons SJ. Phosphorylation of p190 on Tyr1105 by c-Src is necessary but not sufficient for EGF-induced actin disassembly in C3H10T1/2 fibroblasts. J. Cell Sci. 2001;114(Pt 9):1699-1708. doi: 10.1242/jcs.114.9.1699.o Su L*, Agati JM*, Parsons SJ. p190RhoGAP is cell cycle regulated and affects cytokinesis. J Cell Biol. 2003;163(3):571-582. doi: 10.1083/jcb.200308007. *equal authorshipo Manchinelly SAS, Miller JA, Su L, Miyake T, Palmer L, Mikawa M, Parsons SJ. Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis. J Biol Chem. 2010; 285(35)26923-26932. doi: 10.1074/jbc.M110.103804.

• Diabetes research in laboratory of Dr. Patrick Quinn • Phosphoenolpyruvate carboxykinase (PEPCK) gene expression and control by insulin: examination of the roles of various signaling pathways activated by phosphatidylinositol 3-kinase (PI3-K), protein kinase B (PKB), protein kinase C (PKC) and Ras/mitogen-activated protein kinase (Ras/MAPK) to understand which pathway regulates insulin inhibition of PKA-induced PEPCK expression. • Performed cell culture; DNA, RNA and protein assays, CHIP, SDS-PAGE• Trained graduate students• Publicationso Agati, JM, Yeagley D, Quinn PG. Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription. J Biol Chem. 1998;273(30):18751- 18759. doi: 10.1074/jbc.273.30.18751.o Yeagley D, Agati JM, Quinn PG. A tripartite array of transcription factor binding sites mediates cAMP induction of phosphoenolpyruvate carboxykinase gene transcription and its inhibition by insulin. J Biol Chem. 1998;273(30):18743-18750. doi: 10.1074/jbc.273.30.18743.