Formulation and Process Development,Parenteral, Topical and Ophthalmic Pharmaceutical Development Unit,Technical Research and Development,Global Drug DevelopmentPlan, coordinate and supervise Formulation and Process Development activities with Drug Product Project Leads and Formulation Scientists in FPD, Analytical Project Leads and Analytical Scientists in Analytical Research and Development and personnel from other functional groups in the early and late phase development of parenteral, topical and ophthalmic drug products.Plan, coordinate, supervise and monitor the manufacture of drug formulations for preformulation, formulation optimization and exploratory stability studies, preclinical pharmacokinetics, toxicology and pharmacology studies and analytical and microbiological method suitability studies and validations.Author, co-author, review and/or approve Technical Development Plans, Technical Reports, Standard Operating Procedures, Feasibility Evaluation Reports, Clinical Service Form Development Reports, Final Market Image Feasibility Assessment Reports, Technology Transfers, Manufacturing Instructions and Manufacturing Process Transfer Protocols.Author, co-author, review and approve CMC sections of regulatory submission documents, regulatory responses, briefing packages, amendments and supplements.Provide product support for drug products from early stage research through development, approval and post-approval.

R&D Pharmaceutical Products and Technology DevelopmentPlanned, conducted and monitored formulation research and development activities and represented PPTD Pharmaceutics on project teams in the development of topical ophthalmic drug products.Manufactured drug formulations for exploratory preformulation, formulation optimization and stability studies, preclinical pharmacokinetics, toxicology and pharmacology screening and analytical and microbiological method suitability studies and validations.Utilized solid state and other analytical techniques including XRPD, TGA, DSC, Raman spectroscopy, particle size analysis, viscometry, rheology, HPLC and UPLC to characterize new drug candidates and drug products. Wrote technical reports, SOPs and technical transfers and authored relevant sections of regulatory submission documents, regulatory responses, briefing packages, amendments and supplements in support of project elevation from the candidate selection process to proof of concept studies and regulatory submissions.Provided product support for drug products from early stage research through development, approval and post-approval.

Alcon Research, Ltd.R&D PharmaceuticsPlanned, conducted and monitored formulation research activities and represented Pharmaceutics on Glaucoma Research project team in support of glaucoma research testing funnels for topical ophthalmic drug products.Manufactured drug formulations for exploratory preformulation and stability studies, preclinical Pharmacokinetics, Toxicology and Pharmacology screening and Analytical Chemistry and Microbiology method validations.Utilized physical and chemical analytical techniques to characterize new drug candidates and drug products.Wrote technical reports in support of material transfer agreements and project elevation from the candidate selection process to proof of concept studies.

Alcon Research, Ltd.R&D Formulation Development Surgical TherapeuticsPlanned, conducted and monitored formulation research activities and represented Formulation Development Surgical Therapeutics on project teams in the development of ophthalmic surgical drug products and medical devices (ophthalmic irrigating solutions and ophthalmic viscoelastic devices) and topical ophthalmic and otic drug products.Manufactured drug formulations for exploratory preformulation, formulation optimization and stability studies, preclinical Toxicology screening and Analytical Chemistry and Microbiology method validations.Wrote technical reports, SOPs and technical transfers and authored relevant CMC sections of regulatory submission documents, regulatory responses, briefing packages, amendments and supplements in support of new product registrations and product lifecycle management.Provided product support for drug products from early stage research through development, approval and post-approval.

Alcon Research, Ltd.R&D Pharmaceutical SciencesPlanned, conducted and monitored formulation research activities and represented Pharmaceutical Sciences on project teams in the development of topical ophthalmic, otic and nasal drug products.Manufactured drug formulations for exploratory preformulation, formulation optimization and stability studies, preclinical Pharmacokinetics, Toxicology and Pharmacology screening and Analytical Chemistry and Microbiology method validations.Wrote technical reports, SOPs and technical transfers and authored relevant CMC sections of regulatory submission documents, regulatory responses, briefing packages, amendments and supplements in support of new product registration and product lifecycle management.Provided product support for drug products from early stage research through development, approval and post-approval.

Department of ChemistryConducted research in synthetic organic and organometallic chemistry.Conducted computational and in vitro studies of the interactions of DNA with novel synthetic compounds.

Department of ChemistryTaught undergraduate organic chemistry laboratory sections.Proctored and graded examinations and tutored undergraduate chemistry students.

Alcon Laboratories, Inc.R&D Pharmaceutics Research SupportPlanned, conducted and monitored preformulation research activities in the development of potential new drug candidates for the treatment of glaucoma, allergic conjunctivitis and inflammation.Conducted studies of the kinetics of degradation of potential new drug candidates.Manufactured drug formulations for exploratory preformulation and stability studies and preclinical Pharmacokinetics, Toxicology and Pharmacology screening.Developed exploratory analytical HPLC methods and performed chemical and physical analyses to characterize new drug candidates and drug products. Wrote technical reports and SOPs and authored relevant sections of IND submissions.