Jean-Philippe Taquet Email & Phone Number

Visp, VS, CH

Basel, CH

Regulatory CMC: Preparation and/or review of regulatory pharmaceutical documents for small molecules, drug linkers and antibody-drug conjugates: CMC sections of IMPD/IND/NDA/MAA, CTD module 3, US/EU DMF, Quality Overall Summary of MAA, CMC sections of Scientific Advices. Responses to Ad hoc questions and to Grounds for Non-acceptance from the regulatory.

Basel, CH

Paris, Paris, FR

Preparation and/or review of regulatory pharmaceutical documents for small molecules, chemical peptides and antibody-drug conjugates: CMC sections of IMPD/IND/NDA/MAA, CTD module 3 (included variations), US/EU DMF and Quality Overall Summary of MAA. Preparation and/or review of answers to Quality questions during assessments of dossiers by regulatory.

Saint Cloud, FR

Brig, Valais, CH

Chemist responsible for process research and development in organic synthesis: supervision of a laboratory technicians’ team, project management, coordination with QC, QA, and production teams. Written and oral communication with international customers.Custom Synthesis, technical and economic feasibility studies of new molecules and key-intermediates.

Bubendorf, CH

Chemist responsible for API chemical and process development (including peptide liquid phase synthesis): supervision of a laboratory technicians’ team, project management, coordination with QC, QA, and production teams.Development Projects Management: Internal coordination with commercial, analytical, quality, production and regulatory Teams; external.

FR

- Responsable Synthèse Chimique: Synthèse multi-étapes, pré-développement et scale-up de nouvelles molécules énergétiques du type hétérocycles azotés (bitriazoles, pyrazoles, furazanes).; développement et amélioration de procédés bas-coût en chimie des dinitramines.- Développement de projets R&D, recherches bibliographiques, rédaction de rapports techniques.

- Synthèse multi-étapes d’hétérocycles hautement colorés fluorescents (phthalocyanines) et couplage sur des hexapeptides. Etude photophysique pour une application en thérapie photodynamique contre le cancer

- Synthèse multi-étapes de ligands phosphoramidites et oléfiniques chiraux. Application en catalyse de substitution allylique asymétrique: Développement de nouvelles méthodes catalytiques de synthèse énantiosélective d’amines et d’esters allyliques d’intérêt pharmaceutique sous conditions industrielles.- Etude mécanistique du cycle catalytique.

Doctorat, Chimie

Ingénieur, Chimiste