Jean-Sebastien Garrigue Email & Phone Number

Paris, Fr

Évry, Île-De-France, France

Coordination of Global R&D activities in EMEA region (80-100 employees) with registration and launch of several medical devices and medicinal products in ophthalmology (Budget 20-40 m€). Reporting to Corporate Officers (CSO/Global Head of R&D and Head of EMEA region).Member of the European Management Board since 2012 with EU/EMEA business growth from 20m€ to >300m€ sales, expanding from 10 to 50+ countries.

Evry, France

Managing Director (Directeur Général) of Santen SAS (80+ employees) with staff in La Défense (previously Paris and Evry) +sales forces.

Global strategic advisor role reporting to the Chief Medical Officer.- Lead strategic initiatives for the Global Product Development Division (PDD) in collaboration with the Chief Medical Officer (CMO).- Drive product development strategy, including pipeline asset management, digital strategy, and organizational transformation.- Ensure global programs meet regulatory requirements and market needs by fostering cross-functional collaboration and liaising with regions and corporate functions.- Provide senior-level support to the CMO and PDD leadership team.- Oversee regional R&D coordination in EMEA and Asia (100-150 employees).- Chief of staff / deputy head (350-600 employees).

Genève, Suisse

Leadership of a diverse team of 30 staff (MSL, medical directors, MD, Pharm D, PhD) operating in EMEA (>50 countries) with broad portfolio (>30 brands) encompassing glaucoma (Rx, surgical), ocular infections, cataract surgery and ocular surface diseases (dry eye, allergy, ...) (5-10M€ budget). Launch of multiple products and digital adaptation of MA activities during Covid19 outbreak.#Field Excellence, #Multi-channel Medical Education, #Thought Leadership

Leading of an international team (15 researchers) based in Nara, Japan and Evry, France developping new generation of drug delivery systems, smart packaging & innovative injection systems for ophthalmology as part of Global Pharmaceutical Technology Development (CMC).

Leading the Chemical, Manufacturing, and Controls function in Europe at Santen, driving the development and commercialization of innovative ocular drugs.Overseeing a talented CMC team responsible for the entire product lifecycle, from pre-clinical development to commercial manufacturing and quality control.

Evry, France

Leading a team of dedicated pharmacists to provide exceptional patient care and ensure the safe and accurate manufacturing and dispensing of medications.Overseeing all pharmaceutical operations, adherence to regulations, and implementation of best practices.

Supervision of the R&D activities (20 employees) including the Innovation & Research group (IP, Innovation, Research), the Development group (CMC, analytical, formulation, scale up, QC) and the biological evaluation (nonclinical aspects).Pharmaceutical development activities for products at nonclinical and clinical stages (from phase I to phase III/registration): preparation of INDs for phase I & phase III, IMPD for phase III, CTD modules in anticipation of filing, global regulatory strategy.Relationship with KOLs, experts and consultants, interactions with EMEA & FDA (pre-IND, PIP, Scientific advices, Pre-NDA, etc.).Received 2 awards in 2009: the 2009 North American Frost & Sullivan award for the best ocular delivery systems (March 2009), Siemens Innovation award in Life Sciences (June 2009)Filed 9 patents since appointment (out of 16 families of patent applications in total).

Corporate & Business development, preparation of an IPO on Euronext (late cancellation due to financial crisis), participation to 2 fund raising deals (26 m€ + 15m€), Out-licensing & strategic planning.Orchestrated market study & premarketing of a pediatric orphan drug for the treatment of vernal keratoconjunctivitis. Worked on the strategy of implantation of a specialty pharma company in Europe (structure, strategy, cost, timing etc.).

In & Out licensing, due diligences, market survey, market study

Formulation work, preclinical activitiesDevelopment of a nano-emulsifying delivery system (2 patents)Development of Novasorb(r), cationic nanoemulsions for topical ocular delivery Development from formulation to phase I pharmacokinetic trial in cancer patients of an oral self-emulsifying formulation of paclitaxel (published in Br J of Cancer)Development from formulation to phase II of an emulsion-based cyclosporine A eye drop for the treatment of severe dry eye disease.

Créteil, Île-De-France, France

Externship as Pharm. D student in various services (quarterly change) incl. pharmacy department, psychiatry unit, geriatrics & gastroenterology.

Research fellowship on behalf of Battelle Laboratories and the US Department of Energy at the Pacific Northwest National Laboratory, Polymer Science department in Richland, WA, USAI worked on the development of thermosensitive polymers for subcutaneous sustained delivery of insulin.

Artificial Intelligence And Data Science For Leaders, Data Science

Activities and Societies: The eight-week Artificial Intelligence (AI) and Data Science for Leaders program at the University of Chicago is.

Mba (Caae), Business Administration

Activities and Societies: Health group Memorandum on valuation in life sciences (real options, net present value, multiple etc.)

Dea/Msc In Biopharmaceutical Sciences, Pharmaceutical Sciences

Pharm D, Pharmaceuticals, Thèse De Docteur En Pharmacie

Activities and Societies: Association sportive, AEPCM (Vice-Présidence), club oenologie (Présidence)