As programme manager, I work together with the programme director and programme coordinator to further develop the curriculum and the quality of the BMT/BME education programme.

AuteursrechteninformatiepuntBachelor examencommissie

Magee-Womens Research Institute, Pittsburgh PADepartment of Obstetrics, Gynecology & Reproductive Sciences at University of PittsburghCo-Investigator on clinical and basic AHA Go Red For Women Research Project: Women’s Cardiovascular Health and Microvascular Mechanisms: Novel Insights From Pregnancy• Studying microvascular responses to the stress of pregnancy and placenta-related pregnancy disorders which inform later life cardiovascular disease • Sublingual glycocalyx measurement using SDF imaging and vascular assessment using EndoPAT and NICOM• Collected and analyzed basic research (in vivo and in vitro c1q mouse model of preeclampsia) and clinical data (in vivo assessment of vascular functioning in women)• Development of contrast enhanced ultrasound imaging quantification software (Matlab) • Worked with key opinion leaders (KOLs) within research and clinical fields to facilitate management of unique research protocols• Provided scientific, medical, and educational resources and training for researchers and investigators in image/data analysis and interpretation • Presented data to peers and non-scientific KOLs • Developed standard operating procedures (SOPs) and protocols for recruitment, sample collection, processing and storage procedures• Analyzed and reviewed protocols to ensure compliance with appropriate federal, state, institutional policies and institutional review board (IRB) guidelines; Assisted with submission of protocols• Trained and managed medical students, laboratory technician and clinical recruiters• Participated in “Carnegie STEM Girls” to improve academic achievement and increase interest in, and awareness of, STEM (science, technology, engineering and math) topics and careers among economically disadvantaged girls• Completed the Health Sciences Leadership Academy for Early Career Faculty designed to cultivate transformative leaders through shared leadership training

University of Pittsburgh, Pittsburgh PAVascular Medicine Institute• Investigated in an in vivo mouse model the role of XBP-1 in type II epithelial cells in the development of idiopathic pulmonary fibrosis using the γherpes-virus induced pulmonary fibrosis model • Brightfield, fluorescent, confocal and transmission electron microscopy to image type II epithelial cells and murine and human lung tissue• Basic cell culture techniques including murine and human epithelial cell isolation and cell culture; bacterial culture; plasmid purification; transient cell transfection• RNA and DNA extraction from tissue and cells and traditional and real-time PCR• Responsible for planning of long running scientific study projects in rodents• Created project documents including SOPs to comply with good laboratory practice (GLP) and institutional animal care and use committee (IACUC) regulations • Managed lab inventory • Attended the international and interdisciplinary doctoral training program, "Lung Biology and Disease" performing research projects in translational medicine collaborating with scientists and clinicians from all over the world

University of Pittsburgh, Pittsburgh PACenter for Ultrasound Molecular Imaging and Therapeutics at University of Pittsburgh AHA fellowship: The endothelial glycocalyx: A novel cardiovascular therapeutic target• Used intra-vital microscopy (rat cremaster tissue) to study pharmacologic rebuilding of glycocalyx and measure microvascular function and perfusion in the setting of post-ischemic reperfusion • Studied in vivo the cell free layer as mechanism for improved microvascular perfusion after infusion of drag reducing polymers • Micro-embolization and treatment of microvascular micro-embolization in rat hindlimb using microbubbles and long-tone-burst ultrasound• Clinical study to determine sublingual glycocalyx measurement in subjects diagnosed with coronary artery disease or pulmonary hypertension (UPMC-Presbyterian)• Project manager for translational research study on endothelial glycocalyx in biological (human) specimens• In vivo research to study microvascular function and perfusion and data analysis using Matlab• Scientific grant and proposal writing, including budget management• Published and reviewed manuscripts in scientific journals• Instructor of ‘Practicum in Biomedical Engineering’, Carnegie Mellon University course and mentored 9 undergraduate and graduate students from Carnegie Mellon University during internship at University of Pittsburgh

Ph.D., Psychology, University of Maastricht, 2010Dissertation: Role for agonist-induced glycocalyx modulation in coronary flow regulation and oxygen exchange. Application of tracer dilution for determination of glycocalyx volumeDissertation Advisors: Hans Vink, Ph.D., Mark Post, MD. Ph.D., and Jos Spaan, Ph.D.• Experienced developing and optimizing large animal studies and ensuring compliance with appropriate national and institutional policies and DEC (dier experimenten commissie) guidelines• Presented scientific data at national and international meetings• Led interactions with investigators and stakeholders regarding research and budget questions • Trained undergraduate medical students in ‘Spirometry’, ‘Analysis of Signals’, ‘Regulation of blood pressure and flow’ and ‘Vessel wall mechanics’