Jue (George) Wang Email & Phone Number

Toronto, ON, CA

Toronto

• In-depth understanding of small molecule drug discovery from target identification to preclinical studies
• Specialize in ADME, PK, and analytical chemistry to support drug discovery efforts
• Perform in-vitro ADME assays such as membrane permeability, liver metabolic stability, plasma stability, protein binding assay using LCMS to guide Hit and Lead optimization
• Prepare in-vivo samples from mouse plasma and perform plasma drug concentration and metabolite ID analysis using LCMS/MS methods
• Perform intact protein identification for in-house protein production
• Responsible for cell culturing of cancer cell lines

Toronto, Ontario, Canada

• In-depth understanding of small molecule drug discovery from target identification to preclinical studies
• Specialize in ADME, PK, and analytical chemistry to support drug discovery efforts
• Perform in-vitro ADME assays such as membrane permeability, liver metabolic stability, plasma stability, protein binding assay using LCMS to guide Hit and Lead optimization
• Prepare in-vivo samples from mouse plasma and perform plasma drug concentration and metabolite ID analysis using LCMS/MS methods
• Perform intact protein identification for in-house protein production
• Responsible for cell culturing of cancer cell lines

Richmond Hill, Ontario, Canada

• Specialized in liquid and semi-solid dosage such as nasal sprays, ophthalmic solutions, oral solutions, ointments, etc.
• Executed analytical procedures on finished products, stability samples, cleaning validation, and process validation samples according to in-house method, USP, and EP
• Involved in method validation of in-house methods
• Troubleshot instruments and optimized analytical methods
• Led team members in laboratory investigations and prepared CAPA reports
• Maintained compliance to cGMP, cGLP, and all health and safety protocols

Markham, Ontario, Canada

• Executed qualitative and quantitative analytical procedures on a variety of finished products and raw material such as aspirin tablets, acyclovir ointment, etc.
• Deep understanding of USP, EP, and BP
• Interpreted analytical data, validated test result, and outline conclusions of analysis

Toronto, Ontario, Canada

• Focus: investigation of bivalent imidazole molecules' effect on hamster ovary cells and Plasmodium falciparum parasites
• Trained in a BSL-2 laboratory
• Involved in method development, molecule characterization and evaluation
• Performed cell-based assays to determine the IC50 of bivalent imidazole molecules on hamster ovary cells and parasites
• Assessed potency of imidazole molecules on malaria parasites, and selected drug candidates