Julia Amaral Email & Phone Number

Cambridge, Ma, Us

Lawrence Township, Nj, Us

Cambridge, Massachusetts, Us

Cambridge, Massachusetts, Us

- Independent planning, execution, analysis, and presentation of complex experiments and data with the primary goal of furthering the understanding of the proteolytic disease profile of non-alcoholic steatohepatitis (NASH), to aid in the creation of a comprehensive diagnostic platform. - Extensive work with in vivo and in vitro liver models, specifically NASH and HCC, with a focus on hepatocytes and fibroblast cell types. - Development of in vitro experiments from start to finish utilizing cell culture techniques, such as transfection, activation/differentiation of cell types, and cell-based assays. - Assay development and optimization using molecular biology and protein chemistry techniques such as western blot, ELISA, fluorogenic activity (FRET) assay, Luminex, and other plate-based assays.- Strong ability to multi-task and pivot to accommodate rapid company goal shifts. - Daily cross-functional collaboration with chemistry, computational, and biology teams to achieve and exceed company goals. - Direct supervision and management of biology intern.

-Co-authored a peer-reviewed publication assessing high seas tuna fishery (tRFMO) policies for shark and ray bycatch with the goal of identifying current policy gaps and proposing solutions to mitigate future bycatch.

Needham, Ma, Us

- Used radioactive isotopes in a preclinical discovery biology setting in toxicity, drug labeling/targeting, and imaging experiments for large pharmaceutical study sponsors.- Collaborated closely with other functional groups to follow sponsor study protocols and timelines. - Executed large in vivo studies (n>100) with challenging time tables efficiently with precise consideration of radioactive half-life; communicating smoothly with other lab departments to ensure a safe hand off of radioactive materials. - Created comprehensive organizational structures and standard operating procedures to enable smooth lab operations. - Routine handling of mice and rats in accordance with IACUC policies; mastery of dosing of mice and rats (IV, SQ, IP, retro-orbital, oral gavage, intramuscular, intratumoral)- Regularly performed animal surgeries; stereotaxic injections, survival blood collection, tumor inoculation, necropsy, and tissue collection. - Knowledge and implementation of several disease models; e.g. NASH, DSS colitis, Parkinson’s, multiple cancer models, etc.

Santa Cruz, Ca, Us

Santa Cruz, Ca, Us

Santa Cruz, Ca, Us