Founder of CrustOceans, an independent development studio with a social and environmental component.CrustOceans collaborates with different non-profits through the donation of a percentage of the profits generated by its games and products.Our current portfolio includes Kubikol, a puzzle game already published for the iOS and Android platforms and two other games currently under development.As the founder and main developer my responsibilities include:Design and implementation of mobile phone games using Lua and the Corona SDK.Collaborate with graphic designers and musicians for the creation of the art included in the games.Maintenance of the web portal.Set up collaborations with non-profits.

Design and implement the Variant Interpretation Portal (VIP), an innovative data analysis platform that integrates genomic and phenotypic data and enables scientists to formulate new biomarker and target hypothesis.Through the use of the most modern technologies I have been able to develop a highly flexible and intuitive system that provides real time analytics to a wide variety of data types. This new platform have empowered bench scientists to perform analyses that were previously only accessible to computational biology experts.VIP is currently being used for drug sensitivity studies to help identify novel correlations between genomic alterations and different drug response measurements. VIP also supports different initiatives in the Inmuno-oncology and functional genomics space for target identification and validation. Other responsibilities include:Participate in the model characterization efforts within Pfizer.Supervise the development and data management of OASIS, the public cancer genomic portal at Pfizer.Data management for cancer genomic projects.Participate in the analysis and reporting of Pfizer internal datasets.Propose new methods and strategies for knowledge mining.

Lead the design and implementation of the OASIS cancer genomics portal (http://oasis-genomics.org). OASIS is a platform that allows scientist to access and explore genomics data from both public and proprietary data sets. OASIS provides multiple ways to visualize the available data as well as pseudo-programmatic access to the data through the use of the BioMart framework.Since it's inception OASIS has become the main platform to explore and share cancer genomics data within Pfizer and it is frequently used to validate biomarker hypothesis and for the identification of models with specific genomics profiles.Supervise the release of a publicly available version of the OASIS portal using Amazon Web Services. Development of automatic pipelines for analysis and annotation of mutations (SNPs and short indels) and Structural Variation events, with an emphasis in gene fusions (predicted both from WGS and RNA-Seq). Participate in the analysis and reporting of Pfizer internal datasets.Other activities include:Preparation of educational materials for OASIS and provide seminars to colleagues on how to use OASIS. Active participation in the organizing committee of an annual Pfizer "omics" workshops.Collaborate with Research Business Technology Unit in the management and set up of our hardware infrastructure (setting up computer cluster, management of data store system, test of cloud solutions).

Part of the development team of the BioSample database at the EBI: - Assist with web development - Data loading and standardization - Integration of data from other EBI resources.Data management: - Analysis of data integrity - Data integration and standardization - Assist user with data formatting and data uploadProduction management: - Analysis and identification of user requirement. - Configuration of software tools based on user requirement. - Definition of software development and maintenance cycles. - Lead weekly conference calls between the international development and production teams (spread aound 3 countries). - User supportSIMBioMS systems development: - Design and implementation of new functionality in the existing software. - Development of sample data and software testing. - Assist in the design new software tools. - Web designOther: - Writing (documentation and scientific publications) - Teaching

Genome annotation of human genome assemblies (NCBI36 and GRCh37) using computational methods.Designed and developed an algorithm for the integration of manually curated gene annotation and computational based annotation.Development of algorithms for the computational based annotation of genomes.Quality control of genome annotations.Annotation of other Vertebrate Genomes.

Development of three-dimensional structural models for PKD domains of polycystin-1 protein and study of structure-function relation, taking part of the project entitled: "Poliquistosis Renal: Estructura-Función de los Dominios PKD en la Poliquistina 1" (Polycystic kidney disease: Structure and function of PKD domains in polycystin-1), project code PGIDT 04 PXIB 91801 PR.Implementation of a software tool for the automatic alignment, parsing and base pair change annotation of PKD1 gene sequences obtained from direct sequencing compared to PKD1 wild-type sequence.PKDGnosys Database development for the integration of changes detected at the nucleotide sequence level with phenotypical information from ADPKD patients.

Design a method for the separation and proteolytic enzime purification of fish industry subproducts, as part of the project entitled; Research in the field of microbiology and molecular biology in a project to identify and isolate new bacterial strains that can be used in Cheese Industry, at the Department of Microbiology, under the supervision of Full