Senior Director
Current
Tome Biosciences
Feb 2023 - Present
AeroLeads people directory · profile
Jun Jiang Email & Phone Number
Senior Director | Gene Editing therapy | iPSC disease modeling
at
Tome Biosciences
1 work email found
@tome.bio
2 phones found area 508
LinkedIn matched
✓ Verified May 2026
4 data sources
Profile completeness 100%
Current company
Tome Biosciences
Role
Senior Director | Gene Editing therapy | iPSC disease modeling
Location
Greater Boston, United States, United States
Who is Jun Jiang? Overview
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Quick answer
Jun Jiang is listed as Senior Director | Gene Editing therapy | iPSC disease modeling at Tome Biosciences, based in Greater Boston, United States, United States. AeroLeads shows a work email signal at tome.bio, phone signal with area code 508, and a matched LinkedIn profile for Jun Jiang.
Jun Jiang previously worked as Senior Director at Tome Biosciences and Senior Principal Scientist at Tome Biosciences. Jun Jiang holds Doctor Of Medicine (M.D.), Medicine In Pediatrics from China Medical University.
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Email format at Tome Biosciences
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{first}@tome.bio
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Profile bio
About Jun Jiang
A highly motivated and cross-functional team leader with 15+ years of experience in developing gene editing-based gene therapy for liver metabolic diseases and neurological disorders• 15+ years of experience in gene editing (CRISPR, TALENs, ZFNs) technologies including therapeutic applications, generation of in vitro and in vivo disease models, and scientific due diligence. I published part of the work as first author in Nature (Jiang et al 2013, Nature)• Extensive experience in development of CRISPR-based in vivo gene editing therapies (prime editing and PASTE editing) for liver metabolic diseases and neurological disorders • Lead cross-functional team to develop, implement and execute research strategies for guide screen, target identification and lead optimization, and develop iPSC disease models to validate the lead candidates for development candidate (DC) nomination and future IND filing• Experience in using LNP, AAV, electroporation, and lipid-based delivery approaches for genome editing in variety of cell types including primary human hepatocytes (PHH), primary cynomolgus Monkey hepatocytes (PCH), iPSCs, and iPSC-derived neurons/hepatocytes, etc.• Proven track record of designing, cloning, & inserting large therapeutic genes (~22kb) into genome using gene editing technologies. A number of targeting vectors and iPSC lines generated were issued a patent in 2017 (Dosage compensating transgenes and cells, Patent No.: US 9,681,646 B2)• Established dCas9/CRISPRa therapeutic platform to activate/upregulate endogenous gene expression for treatment of neurological diseases in iPSC-derived neurons
Listed skills include Human Genetics, Stem Cell Research, Genome Editing, Molecular Biology, and 24 others.
Current workplace
Jun Jiang's current company
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Tome Biosciences
7 roles
Jun Jiang work experience
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Senior Principal Scientist
Tome Biosciences
Feb 2022 - Feb 2023
Principal Scientist
Tome Biosciences
Using next generation of gene editing technologies to deliver a therapeutic gene for treating genetic disorders
May 2021 - Feb 2022
Scientist
Use gene editing technologies to generate disease models for neurological diseases in iPSCsEstablish CRISPRa platform to up-regulate gene expression for a number of neurological diseases with haploinsufficient mutations
May 2019 - Apr 2021
Assistant Professor
- Project: 1. Using iPSC-based trisomy silencing model to identify key regulators underlying cognitive impairments in Down syndrome.2. Generation of trisomy correction mouse models of Down syndrome.3. Transplantation of.
- The assays and techniques used for these projects included: construction of large targeting vectors, genome editing technologies, electroporation, generation of gene editing based stem cell lines, differentiation of.
- Primary responsibility (as a principle investigator and co-investigator) included project and assay development, supervision and technique development of one postdoc, one graduate student and one research associate.
- Invited talks: 1. Silencing the extra chromosome responsible for Down syndrome. The 10th International Conference on Genomics, Shenzhen, 10/24/20152. Using XIST to silence trisomy 21: implications for cell and.
Feb 2014 - Apr 2019
Instructor
- Project: Using genome editing technology to insert large XIST transgene into chromosome 21 and silence the extra chromosome in Down syndrome stem cells.
- Patent: Dosage compensating transgenes and cells, 20140294785.
- Publication: Translating dosage compensation to trisomy 21. Nature, 2013, 500: 296–300.
- Invited talks: 1. Translating Dosage Compensation to Trisomy 21. Using Stem Cells to Model and Treat Human Disease, Los Angeles, 11/23/20132. Translating Dosage Compensation to Trisomy 21. Cell & Developmental Biology.
Apr 2012 - Jan 2014
Postdoctoral Fellow
- Project: Using genome editing technology to insert large XIST transgene into chromosome 21 and silence the extra chromosome in Down syndrome stem cells.
- The molecular and cellular mechanisms of neuronal axon growth and guidance.
- Publication: 1. Negative guidance factor-induced macropinocytosis in the growth cone plays a critical role in repulsive axon turning. J Neurosci, 2009, 29(34): 10488-98.2. Myosin IIB isoform plays an essential role in.
Jul 2005 - Apr 2012
2 education records
Jun Jiang education
Doctor Of Medicine (M.D.), Medicine In Pediatrics
China Medical University
Doctor Of Philosophy (Ph.D.), Molecular Genetics Of Pediatrics
China Medical University
FAQ
Frequently asked questions about Jun Jiang
Quick answers generated from the profile data available on this page.
What company does Jun Jiang work for?
Jun Jiang works for Tome Biosciences.
What is Jun Jiang's role at Tome Biosciences?
Jun Jiang is listed as Senior Director | Gene Editing therapy | iPSC disease modeling at Tome Biosciences.
What is Jun Jiang's email address?
AeroLeads has found 1 work email signal at @tome.bio for Jun Jiang at Tome Biosciences.
What is Jun Jiang's phone number?
AeroLeads has found 2 phone signal(s) with area code 508 for Jun Jiang at Tome Biosciences.
Where is Jun Jiang based?
Jun Jiang is based in Greater Boston, United States, United States while working with Tome Biosciences.
What companies has Jun Jiang worked for?
Jun Jiang has worked for Tome Biosciences, Biogen, and Umass Medical School.
How can I contact Jun Jiang?
You can use AeroLeads to view verified contact signals for Jun Jiang at Tome Biosciences, including work email, phone, and LinkedIn data when available.
What schools did Jun Jiang attend?
Jun Jiang holds Doctor Of Medicine (M.D.), Medicine In Pediatrics from China Medical University.
What skills is Jun Jiang known for?
Jun Jiang is listed with skills including Human Genetics, Stem Cell Research, Genome Editing, Molecular Biology, Cell Biology, Cell Culture, Cytogenetics, and Generation Of Gene Editing Based Stem Cell Lines.
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