Joshua Kane Email & Phone Number
@nurixtx.com
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Who is Joshua Kane? Overview
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Joshua Kane is listed as Drug discovery leader at Nurix Therapeutics, a with 368 employees, based in San Francisco, California, United States. AeroLeads shows a work email signal at nurixtx.com and a matched LinkedIn profile for Joshua Kane.
Joshua Kane previously worked as Scientist at Nurix Therapeutics and Postdoctoral Fellow at Novartis Institutes For Biomedical Research (Nibr). Joshua Kane holds Doctor Of Philosophy (Phd), Biochemistry And Molecular Biology from University Of California, San Francisco.
Email format at Nurix Therapeutics
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AeroLeads found 1 current-domain work email signal for Joshua Kane. Compare company email patterns before reaching out.
About Joshua Kane
Mission-driven drug discovery scientist with 7+ years industry experience strongly committed to addressing unmet medical needs, with expertise in project team leadership, induced proximity platforms (including targeted protein degradation), oncology and infectious diseases indications, mammalian cell culture, molecular biology, and data analysis.• Highly experienced in mammalian cell culture (primary and cell lines), cell and molecular biology, virology, automated microscopy-based assays, mode-of-action validation studies, and data analysis.• Expertise in study design, execution, analysis, and presentation, with adherence to project timelines.• Biology team leader on multiple drug discovery programs in highly cross-functional team environments• Supervising research team• Excellence in communication, collaboration, and writing, with strong emphasis on team-oriented, milestone-driven activities• Effective in hybrid work environments (proficiency with Microsoft Teams, Zoom, GoToMeeting)** Technical expertise **__Cell culture__• Mammalian cell culture (primary cells and cell lines) • Lentiviral transduction • Virology• RNAi / CRISPR interference (CRISPRi) • Targeted protein degradation• Drug treatment / dose-response assays / rescue studies / viability studies• MOA determination / validation studies• Transfection (transient and stable)• Cell line generation• Clonal line development / isolation / expansion • Plate-based immunofluorescent assays (ImageXpress) • Multicolor flow cytometry • in vitro click chemistry__Molecular biology__• PCR and RT-qPCR • Primer design • Cloning • Site-directed mutagenesis • Plasmid construction / design / synthesis• cDNA generation • Western blotting / immunoblotting• Automated immunoblotting (ProteinSimple Jess)• Lysate fractionation • Virus generation and purification__Biochemistry and biophysics__• Protein affinity purification (native, denaturing, tandem affinity purification) • Protein quantification (BCA)• Protein dialysis / buffer exchange • in vitro labeling (biotin, dyes, click chemistry reagents) • SPR (Biacore T100/200, 8K) • BLI (Octet) • Protein-compound and protein-protein binding assays__Data analysis__• High proficiency with Excel, Python, Prism Graphpad, and R (incl. Shiny app development) • High proficiency with platform-specific data analysis software (XLFit, Cellprofiler, Biacore evaluation software, ForteBio data analysis). • Experienced in analyzing public and proprietary datasets, including proteomics and gene knockdown/knockout datasets.
Listed skills include Bioinformatics, Proteomics, Molecular Biology, Western Blotting, and 10 others.
Joshua Kane's current company
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Joshua Kane work experience
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Role listed
Scientist
Postdoctoral Fellow
• Characterized anti-viral compounds targeting BK and JC polyomaviruses, including determining efficacy (EC50, CC50) and developing exploratory assays to detail mechanism of action. • Composed manuscript (first-author) describing anti-viral peptide targeted polyomavirus capsid (in revision; pre-print on bioRxiv).• Validating and profiling early-stage compounds using SPR (Biacore T100/200 and 8K) and BLI (ForteBio Octet) biophysical platforms, performing protein-compound and protein-protein binding assays, optimizing relevant assays.• Contributing to active projects as team member, presented efforts in local project-team, site-wide, and inter-site meetings.• Engaged in leadership role as site postdoc representative.
Postdoctoral Researcher
Krogan Lab, UCSF Mission BayProject: Identify Novel HIV-Host Interactions• Identified novel HIV Vif E3 ligase targets using global ubiquitylation profiling (Ubi-Scan) and performing subsequent data analysis using in-lab built tools.• Collaborated on CRISPRi-based HIV genetic screening and interaction profiling platform in human T-cell lines (CEMT4, SupT1).• Optimized large-scale harvesting of HIV-1 virus and enrichment of infected cells for genetic screen
Phd Student
Research Advisor: Dr. Nevan J. Krogan• Investigated evolution of host-viral interactions, leveraging affinity purification-mass spectrometry technology, using HIV-1 Vif E3 ligase as model.• Validated findings with follow-up investigation using multiple mammalian (human and non-human) cell lines, small-molecule inhibitors, and RNAi.• Discovered lineage-specific, consequential viral-host interactions in Lentivirus genus and published results as first-author in Cell Reports (video abstract: youtu.be/pRMoXLJKPNc).• Key leadership role in guiding international collaboration at UCSF, U. of Minnesota, and U. of Iceland.
Undergraduate Student Researcher
Research Advisor: Dr. Michael Freeling• Developed with graduate student mentor web-based comparative genomics platform CoGe (http://genomevolution.org/coge/); accomplishments include designing front-end web interface, coding Perl-based wrappers for established genomics tools, and setting up documentation wiki.• Led investigation, under own initiative, into the evolution of a tandem gene array in A. thaliana and A. lyrata using CoGe platform and other phylogenetics tools.• Published undergraduate research as first-author in Journal of Molecular Evolution.
Colleagues at Nurix Therapeutics
Other employees you can reach at nurixtx.com. View company contacts for 368 employees →
Thiago Grigolo
Colleague at Nurix TherapeuticsGreater Houston, United States
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Jamie F.
Colleague at Nurix TherapeuticsPalo Alto, California, United States
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Victoria Louie
Colleague at Nurix TherapeuticsDaly City, California, United States
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Graham Carlson
Colleague at Nurix TherapeuticsSpring, Texas, United States
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Chad Hewitt
Colleague at Nurix TherapeuticsSan Francisco, California, United States
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Kevin Santiago
Colleague at Nurix TherapeuticsUnited States
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Brent Murphy
Colleague at Nurix TherapeuticsSan Francisco, California, United States
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Tania Silva
Colleague at Nurix TherapeuticsSan Francisco, California, United States
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Rishab Iyer
Colleague at Nurix TherapeuticsSan Francisco, California, United States
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Tim Kane
Colleague at Nurix TherapeuticsSan Francisco, California, United States
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Joshua Kane education
Doctor Of Philosophy (Phd), Biochemistry And Molecular Biology
Bachelor Of Arts (Ba), Biochemistry And Molecular Biology
Frequently asked questions about Joshua Kane
Quick answers generated from the profile data available on this page.
What company does Joshua Kane work for?
Joshua Kane works for Nurix Therapeutics.
What is Joshua Kane's role at Nurix Therapeutics?
Joshua Kane is listed as Drug discovery leader at Nurix Therapeutics.
What is Joshua Kane's email address?
AeroLeads has found 1 work email signal at @nurixtx.com for Joshua Kane at Nurix Therapeutics.
Where is Joshua Kane based?
Joshua Kane is based in San Francisco, California, United States while working with Nurix Therapeutics.
What companies has Joshua Kane worked for?
Joshua Kane has worked for Nurix Therapeutics, Novartis Institutes For Biomedical Research (Nibr), Ucsf, and University Of California, Berkeley.
Who are Joshua Kane's colleagues at Nurix Therapeutics?
Joshua Kane's colleagues at Nurix Therapeutics include Thiago Grigolo, Jamie F., Victoria Louie, Graham Carlson, and Chad Hewitt.
How can I contact Joshua Kane?
You can use AeroLeads to view verified contact signals for Joshua Kane at Nurix Therapeutics, including work email, phone, and LinkedIn data when available.
What schools did Joshua Kane attend?
Joshua Kane holds Doctor Of Philosophy (Phd), Biochemistry And Molecular Biology from University Of California, San Francisco.
What skills is Joshua Kane known for?
Joshua Kane is listed with skills including Bioinformatics, Proteomics, Molecular Biology, Western Blotting, Protein Expression, Python, Mammalian Cell Culture, and Affinity Purification.
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