Karen founded Lusun Wyatt in 1999. Headquartered in Beijing, Lusun is the pioneer of China’s Medical Education Simulation Industry, connecting the most advanced products from Europe and the US to medical education institutions in ChinaOver the years, Lusun served more than 15 major industry producers as their strategic partner and exclusive distributor for China, covering the widest range of healthcare education disciplines and specialties with the most comprehensive product and software portfolio. Lusun had six subsidiaries across China, served over 1,500 teaching hospitals, 350 vocational colleges for Allied Healthcare and 180 Medical Schools. Fueled by Karen’s innovative spirit, Lusun develop creative ways to engage global influences in medical education through the ‘Train the Trainer’ model, bridging Western accreditation institutions and KOLs with Chinese peers and providing exceptional total solution services.

Responsible for all overseas resource management and healthcare M&A projects, investment and financing services and other investment banking business resources expansion and investor relations maintenance.

China Pathways was founded in 2007 to specialize in providing education consulting services to students and institutions in the UK and China. Karen joined China Pathways in 2017 to strengthen the firm's outreach in medical education.

Coherent is a world leading manufacturing of science and medical lasers. Karen led the opening of its headquarters in Beijing, with subsequent expansion of five more offices in China and ASEAN countries

Karen led multinational business transactions for chemical and energy products and led the business innovation unit. In London and later Hong Kong, Karen created the triangular trading model and was responsible for over RMB 800 million of International entrepot trading business.