Karen Baker

Karen Baker Email and Phone Number

Formulation/Assay Development, Gene Therapy @ Spark Therapeutics, Inc.
philadelphia, pennsylvania, united states
Karen Baker's Location
Philadelphia, Pennsylvania, United States, United States
Karen Baker's Contact Details

Karen Baker work email

Karen Baker personal email

n/a
About Karen Baker

A multifaceted scientist with masters degrees in pharmacology and biochemistry and three years of gene therapy characterization experience, specializing in subvisible particle analysis. Established new biophysical assays and technologies for high throughput formulation applications to optimize storage buffers for improved AAV stability. Completed a graduate degree in Biochemistry focused on Molecular Diagnostics and Biomimetics at Arizona State University. The projects focus on mRNA origami applications in vaccines, and bioconjugation chemistry.Dissertation project at the University of Oxford provided novel insight into the physiological disease pathology of Niemann Pick type C that can be used for future pharmaceutical development.

Karen Baker's Current Company Details
Spark Therapeutics, Inc.

Spark Therapeutics, Inc.

View
Formulation/Assay Development, Gene Therapy
philadelphia, pennsylvania, united states
Website:
sparktx.com
Employees:
583
Karen Baker Work Experience Details
  • Spark Therapeutics, Inc.
    Htpd Formulation Scientist
    Spark Therapeutics, Inc. Feb 2021 - Present
    Philadelphia, Pennsylvania, United States
    Optimized formulation storage buffers for increased AAV stability using high throughput applications, and investigated the degradation pathways/kinetics of vectors. Instruments: Halo Labs Aura (FMM/BMI), Agilent/Wyatt SEC/MALS, Waters UPLC/IEX, NanoTemper Prometheus (DSF), Beckman Coulter HIAC, Thermo-Fisher UPLC/IEX, Wyatt and Malvern DLS/SLS
  • Arizona State University
    Graduate Student
    Arizona State University Aug 2022 - May 2024
    Tempe, Arizona, United States
    Worked on two projects: (1) making an mRNA origami vaccine that serves as its own delivery platform and (2) making a synthetic antibody using varied bioconjugation methods.
  • Gene Therapy Program | University Of Pennsylvania
    Analytical Associate 3
    Gene Therapy Program | University Of Pennsylvania Jun 2019 - Feb 2021
    Philadelphia, Pennsylvania
    Utilized analytical and biophysical technologies to better understand and characterize adeno-associated viral (AAV) vectors. Created SEC/MALS assay for determining empty:full ratio of vectors.Instruments: Agilent/Wyatt SEC/MALS, Wyatt DLS and DLS/SLS, Thermo-Fisher UHPLC/ESI/MS (Orbitrap)
  • University Of Oxford
    Graduate Student
    University Of Oxford Oct 2017 - Nov 2018
    Oxford, United Kingdom
    Master's dissertation: Effect of Miglustat on myelination in Niemann Pick type C using a DRGN/OPC co-culture systemInvestigated hypomyelination manifestation in Niemann Pick type C, whether the signaling pathway originates from oligodendrocytes or neurons.
  • Grand Canyon University
    Adjunct Faculty Instructor
    Grand Canyon University Dec 2016 - May 2017
    Phoenix, Arizona
    Taught Introductory Chemistry laboratory, including independently supervising undergraduate students during lab and developing course material.Served as an instructional assistant for 'Introduction to Chemistry, Biochemistry, and Organic Chemistry' and 'Crime Scene Processing’ courses.
  • The Center For Forensic Science Research & Education
    Chemistry Intern
    The Center For Forensic Science Research & Education Jun 2016 - Aug 2016
    Willow Grove, Pennsylvania
    Analyzed illicit drug and pharmaceutical samples using a variety of biophysical technologies and analytical techniques.Instruments: Water's UPLC/QTOF, Agilent GC/MS (QQQ)
  • Arizona State University
    Analytical Chemistry Laboratory Assistant
    Arizona State University Jan 2016 - May 2016
    New College Of Interdisciplinary Arts And Sciences
    Chemically identified the structure of the antiviral compound in lemon balm using GC/MS and hNMR,
  • Arizona State University
    Chemistry And Biology Tutor
    Arizona State University Feb 2014 - May 2016
    University Academic Success Programs
    Tutored general, organic, and analytical chemistry as well as biology, biochemistry, and statistics.
  • Arizona State University
    Research Assistant
    Arizona State University Oct 2013 - May 2016
    School Of Criminology And Criminal Justice
    Investigated the relationship between gang embeddedness and delinquency using historical data by developing and implementing a new data entry protocol for expedited data analysis. Supervised 5 undergraduate students and trained them in data processing procedures.Presented at annual poster symposiums at Arizona State University and won first place in 2015 and 2016 competitions, and presented at the 2015 American Society of Criminology annual conference.
  • Arizona State University
    Microbiology Laboratory Assistant
    Arizona State University Jun 2015 - Jan 2016
    School Of Life Sciences
    Extracted and isolated bacteria from Amazon soil samples to discover novel species of Acidobacteria and performed DNA extraction and PCR amplification on bacterial isolates.

Karen Baker Skills

Organized Multi Tasker Learning Quickly Always Punctual Eye For Details Spss Html Microsoft Office Organic Chemistry Visual Arts Data Analysis Research Statistics Microsoft Excel Microsoft Word

Karen Baker Education Details

Frequently Asked Questions about Karen Baker

What company does Karen Baker work for?

Karen Baker works for Spark Therapeutics, Inc.

What is Karen Baker's role at the current company?

Karen Baker's current role is Formulation/Assay Development, Gene Therapy.

What is Karen Baker's email address?

Karen Baker's email address is ka****@****asu.edu

What is Karen Baker's direct phone number?

Karen Baker's direct phone number is +148027*****

What schools did Karen Baker attend?

Karen Baker attended University Of Oxford, Arizona State University, Arizona State University, University Of Pennsylvania.

What are some of Karen Baker's interests?

Karen Baker has interest in Children, Badminton, Traveling, Art Museums, Criminology, Criminal Investigation, Toxicology, Science And Technology, Tennis, Drawing.

What skills is Karen Baker known for?

Karen Baker has skills like Organized Multi Tasker, Learning Quickly, Always Punctual, Eye For Details, Spss, Html, Microsoft Office, Organic Chemistry, Visual Arts, Data Analysis, Research, Statistics.

Who are Karen Baker's colleagues?

Karen Baker's colleagues are Jason Marshall, Mpas, Pa-C, Nathan Springman, Harry Page, Fred Daddi, Rui Zhang, Scott Hocking, Alexander Radzievsky Jr.

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