Karine Roversi, Ph.D. Email and Phone Number

- Perioperative Centre for Outcomes Research group | Centre for Outcomes Research and Evaluation (CORE)- Clinical trials- Pain management

Alan Edwards Centre for Research on Pain

Talbot labProject Focus: Leading two major projects investigating the role of neurons in the tumor microenvironment, with a particular emphasis on ATF3-expressing neurons.Key Research Skills:1. Project Management and Strategic Planning: Oversee and execute all in vivo and in vitro experiments related to tumor-innervating neurons.2. Collaboration: Working closely with renowned researchers from both Canada and the USA to drive project outcomes and insights.3. Technical Expertise:• Cell culture techniques• Flow cytometry setup and data analysis• Quantitative PCR (qPCR)• ELISA• Immunohistochemistry across varied tissue samplesAdditional Research:Evaluating the efficacy of novel drugs on preclinical pain responses using both in vitro and in vivo methods.Technical Skills:• Calcium imaging• Advanced microscopy techniques• Cell culture methodologies• Behavioral assays to assess pain

Talbot labProject Focus: Leading and collaborating on projects that explore the interactions of nociceptor neurons within the tumor microenvironment, with a particular emphasis on CD8 T cell exhaustion and CGRP release responses.Key Research Skills:1. Project Management and Strategic Planning: Designed and executed both in vivo and in vitro experiments related to tumor-innervating neurons, which resulted in a publication in the prestigious Nature journal as a co-author.2. Collaboration: Collaborated in multi-team research projects on cancer immunology, neuro-immunology and pain, resulting in 2 journal articles publications and +5 fellowships and awards.3. Technical Expertise:• Mastery in cell culture methodologies• Proficient in in vivo techniques• Flow cytometry (up to 11 colors) setup and data analysis• qPCR• ELISA• Immunohistochemistry across diverse tissue types• Microscopy• Practical application of optogenetics

Project Focus: Leading two primary projects investigating the impact of environmental influences on anxiety, depression behaviors, and molecular changes in rodents.Key Research Skills and Achievements:1. Project Management and Strategic Planning:• Orchestrated and implemented all in vivo experiments.• Publication of 2 research papers.• Collaboration on several projects, resulting in <15 paper publications.2. Technical Expertise:• Proficiency in in vivo techniques.• Behavioral analysis.• Polymerase Chain Reaction (PCR).• Western Blotting.• Advanced molecular techniques.• Conducted immunohistochemistry on brain samples.• Microscopy expertise.3. Communication Skills:• Delivered presentations at conferences, seminars, and lab meetings.• Demonstrated strong written communication abilities.