Multi-Level support, project lead and specification for Edgar software-as-a-service:Specialist support on simulating and optimizing energy systems, especially for heat and power from single buildings to quarters to commerce and industry. Multi-objective optimization and direct comparisons between generator concepts allow to balance economic, ecologic, and technical requirements.Project lead and specification in software development, transforming customer requests into codable… Show more Multi-Level support, project lead and specification for Edgar software-as-a-service:Specialist support on simulating and optimizing energy systems, especially for heat and power from single buildings to quarters to commerce and industry. Multi-objective optimization and direct comparisons between generator concepts allow to balance economic, ecologic, and technical requirements.Project lead and specification in software development, transforming customer requests into codable algorithms. Show less

Contributing image analysis, algorithmic and coding experience in multiple collaborations. Continuing and expanding my PhD topic of robust defect identification in image data.- analysing orientations and local alignment for confocal light microscopy images of zebrafish optical cup [publication https://doi.org/10.1016/j.cub.2022.09.034 using MATLAB code https://dx.doi.org/21.11101/0000-0007-F43E-1]- analysing orientations, local and global alignment for each photoreceptor within… Show more Contributing image analysis, algorithmic and coding experience in multiple collaborations. Continuing and expanding my PhD topic of robust defect identification in image data.- analysing orientations and local alignment for confocal light microscopy images of zebrafish optical cup [publication https://doi.org/10.1016/j.cub.2022.09.034 using MATLAB code https://dx.doi.org/21.11101/0000-0007-F43E-1]- analysing orientations, local and global alignment for each photoreceptor within electron microscopy images of mouse retinas- porting code for robust defect identification from MATLAB to Python [open source Jupyter notebook: https://git.mpi-cbg.de/mosaic/software/bio-imaging/robust-defect-identification/]- extending robust defect identification to irregular collections of discretization points and to curved surfaces Show less

Doctoral Candidate with Prof. Dr. Ivo Sbalzarini, MOSAIC group at Max Planck Institute for Molecular Cell Biology and Genetics (MPI-CBG), Dresden, and at the Center for Systems Biology Dresden (CSBD). The highly collaborative, interdisciplinary, and multi-national environment at the MPI-CBG and CBSD allowed me to independently explore different topics related to biology, biophysics, imaging, image processing, modelling and simulation, and to formulate the research question of my PhD on… Show more Doctoral Candidate with Prof. Dr. Ivo Sbalzarini, MOSAIC group at Max Planck Institute for Molecular Cell Biology and Genetics (MPI-CBG), Dresden, and at the Center for Systems Biology Dresden (CSBD). The highly collaborative, interdisciplinary, and multi-national environment at the MPI-CBG and CBSD allowed me to independently explore different topics related to biology, biophysics, imaging, image processing, modelling and simulation, and to formulate the research question of my PhD on my very own: How much to trust into the results of automated image analysis?Specifically, I worked out a spatially resolved uncertainty quantification for topological defects, which I termed "robust" defect identification. Thereby, topological defects (aka singular points) are a feature of vector and orientation fields with intriguing connections to shape, geometry and their dynamics.Starting from the mathematical definition of topological defects, and thoroughly studying its discretisation for pixelated data, I developed a measure of reliability for topological defects that are identified in noisy data, with applications from liquid crystal physics to textures to bio-medical images.Applying the newly developed methodologies to my collaborators' microscopy images of cell sheets during development allows to extract biophysical parameters that were not accessible by previous methods. This way, robust defect identification contributes to the understanding and modelling of biological tissue as active material.This position also included teaching of Saptiotemporal Modelling and Simulation to students, and supervision of course works and projects for TU Dresden students and international interns. Show less

Scientific Employee with Lutz Brusch at the ZIH (Zentrum für Informationsdienste und Hochleistungsrechnen / Center for Information Services and High Performance Computing) of the Technical University DresdenI transferred the theory of magnetism to biological tissues, where the polarity of each cell helps the cell orient themselves within the tissue.Extending the theory for dynamic cell replacement and studying it in my own simulation code [Python] showed the impact of cell turnover… Show more Scientific Employee with Lutz Brusch at the ZIH (Zentrum für Informationsdienste und Hochleistungsrechnen / Center for Information Services and High Performance Computing) of the Technical University DresdenI transferred the theory of magnetism to biological tissues, where the polarity of each cell helps the cell orient themselves within the tissue.Extending the theory for dynamic cell replacement and studying it in my own simulation code [Python] showed the impact of cell turnover on the susceptibility of tissue-scale polarity on external stimuli.[extension of Master thesis, published in JRS Interface: http://dx.doi.org/10.1098/rsif.2017.0466] Show less