Karsten Baumgärtel

Karsten Baumgärtel Email and Phone Number

Discovery & Translational Biology I Neuroscience & Rare Disease I Innovative Scientific Leadership I Strategy Development & Implementation I Collaborative Research I Team Building & Mentoring @ Refactor BioSciences
Karsten Baumgärtel's Location
San Diego, California, United States, United States
About Karsten Baumgärtel

Strategic and innovative leader that enjoys navigating both the bigger scope and intricate details of research endeavors. Specialized in expanding and advancing R&D portfolios by leveraging his expertise in early drug discovery and translational biology and his ability to work seamlessly with business development, identify new opportunities, and form alliances. Characterized by an unwavering dedication to utilizing scientific knowledge for the betterment of patient care and a profound desire to make a tangible difference in people's health.

Karsten Baumgärtel's Current Company Details
Refactor BioSciences

Refactor Biosciences

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Discovery & Translational Biology I Neuroscience & Rare Disease I Innovative Scientific Leadership I Strategy Development & Implementation I Collaborative Research I Team Building & Mentoring
Karsten Baumgärtel Work Experience Details
  • Refactor Biosciences
    Co-Founder
    Refactor Biosciences Jul 2024 - Present
  • Amplio Consulting Llc
    Owner
    Amplio Consulting Llc Jan 2024 - Present
    Offering companies and patient groups consulting services within my areas of expertise.
  • Alagille Syndrome Alliance
    Scientific Research Coordinator
    Alagille Syndrome Alliance Jan 2024 - Present
  • Travere Therapeutics
    Director, Translational Biology
    Travere Therapeutics Apr 2022 - Dec 2023
    Pipeline Progression and Expansion, Project Lead• Led a multi-center discovery program through screening activities on multiple different assay platforms and hit triaging.• Designed research strategy to direct and streamline external innovation efforts.• Developed and presented critical diligence insights to senior management to support in-licensing and acquisition go/no-go decisions.• Established and managed collaborations with top-tier academic institutions for existing and new research directions.• Developed and implemented translational strategies for programs in hepatology, and inborn errors of metabolism.
  • Travere Therapeutics
    Associate Director, Translational Biology
    Travere Therapeutics Apr 2020 - Apr 2022
    San Diego, California, United States
    • Worked closely with BD to assess pipeline expansion opportunities in nephrology, hepatology, and neurology.• Helped transition a newly acquired program to Travere.• Led a multi-center discovery program in the development of assay platforms and disease relevant cellular models of multiple different levels of complexity.
  • Travere Therapeutics
    Principal Scientist
    Travere Therapeutics May 2018 - Apr 2020
    San Diego, California, United States
    • Championed unique collaborative research agreement with the National Center for Advancing Translational Sciences (NCATS) and served as the alliance manager and scientific lead. Generated mechanistic insights into disease pathogenesis to support selection of appropriate screening assays and translational models.• Identified pipeline expansion opportunities in neurology, nephrology and hepatology.• Spearheaded exploration and due diligence of new modalities with focus on Neurology and Hepatology.• Provided preclinical research support for neurological and nephrological indications in clinical programs and regulatory filings.• Helped develop and implement translational strategies for program in neurology.
  • Dart Neuroscience Llc
    Group Leader, Target Validation, And Project Lead
    Dart Neuroscience Llc Sep 2012 - Feb 2018
    San Diego, California, United States
    • Spearheaded and led a multidisciplinary drug discovery program within neurology.• Optimized and streamlined target discovery and prioritization by leading a cross-functional project team.• Collaborated with Bioinformatics to develop custom database tools for knowledge capture and target prioritization.• Successfully identified and validated novel targets, promoting several to project status.• Established mechanisms of action (MOA) for target genes related to the indication of interest.• Explored new indications compatible with existing clinical candidates.• Pioneered new technologies and approaches, including virally delivered shRNA.• Served as an IACUC member and DEA representative.
  • The Scripps Research Institute
    Postdoctoral Researcher
    The Scripps Research Institute Aug 2008 - Sep 2012
    San Diego, California, United States
    Investigated neuronal circuits supporting cognitive function in vivo. • Developed new research directions and technologies utilizing chemo- and optogenetics.• Initiated collaborations with leading laboratories at world renowned institutions. • Supervised several technicians, trained PhD student and managed mouse colony.• Contributed to research into mechanisms of epilepsy.
  • University Of Zurich
    Postdoctoral Researcher
    University Of Zurich Jul 2007 - Jun 2008
    Zurich, Switzerland
    Spearheaded and managed innovative collaboration with bioinformatician and proteomics expert to explore novel data sets, contextualize them and understand their significance.
  • Eth Zurich
    Phd Student
    Eth Zurich Mar 2003 - Jun 2007
    Zurich, Switzerland
    Examined molecular factors determining cognitive performance in a collaboration with three world-renowned laboratories as part of an HFSP grant.• Generated new conditional transgenic mouse lines using cutting edge technology. Managed mouse colony of over 15 different transgenic lines with the assistance of direct report.• Conducted biochemical, molecular and behavioral assays to examine phenotypes in mouse models.• Contributed to research into mechanisms of ischemia and schizophrenia.
  • Max-Planck Institute For Psychiatry
    Masters Student
    Max-Planck Institute For Psychiatry May 2001 - Apr 2002
    Munich, Bavaria, Germany
    Researched the molecular mechanisms of Down Syndrome with focus on the kinase Dyrk1A. • Acquired solid laboratory skill set at one of Europe’s top research institutions.

Karsten Baumgärtel Education Details

Frequently Asked Questions about Karsten Baumgärtel

What company does Karsten Baumgärtel work for?

Karsten Baumgärtel works for Refactor Biosciences

What is Karsten Baumgärtel's role at the current company?

Karsten Baumgärtel's current role is Discovery & Translational Biology I Neuroscience & Rare Disease I Innovative Scientific Leadership I Strategy Development & Implementation I Collaborative Research I Team Building & Mentoring.

What schools did Karsten Baumgärtel attend?

Karsten Baumgärtel attended Eth Zürich, Ludwig-Maximilians-Universität München, University Of Technology Sydney.

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