Karsten Baumgärtel Email & Phone Number

Offering companies and patient groups consulting services within my areas of expertise.

• Pipeline Progression and Expansion, Project Lead
• Led a multi-center discovery program through screening activities on multiple different assay platforms and hit triaging.
• Designed research strategy to direct and streamline external innovation efforts.
• Developed and presented critical diligence insights to senior management to support in-licensing and acquisition go/no-go decisions.
• Established and managed collaborations with top-tier academic institutions for existing and new research directions.
• Developed and implemented translational strategies for programs in hepatology, and inborn errors of metabolism.

San Diego, California, United States

• Worked closely with BD to assess pipeline expansion opportunities in nephrology, hepatology, and neurology.
• Helped transition a newly acquired program to Travere.
• Led a multi-center discovery program in the development of assay platforms and disease relevant cellular models of multiple different levels of complexity.

San Diego, California, United States

• Championed unique collaborative research agreement with the National Center for Advancing Translational Sciences (NCATS) and served as the alliance manager and scientific lead. Generated mechanistic insights into.
• Identified pipeline expansion opportunities in neurology, nephrology and hepatology.
• Spearheaded exploration and due diligence of new modalities with focus on Neurology and Hepatology.
• Provided preclinical research support for neurological and nephrological indications in clinical programs and regulatory filings.
• Helped develop and implement translational strategies for program in neurology.

San Diego, California, United States

• Spearheaded and led a multidisciplinary drug discovery program within neurology.
• Optimized and streamlined target discovery and prioritization by leading a cross-functional project team.
• Collaborated with Bioinformatics to develop custom database tools for knowledge capture and target prioritization.
• Successfully identified and validated novel targets, promoting several to project status.
• Established mechanisms of action (MOA) for target genes related to the indication of interest.
• Explored new indications compatible with existing clinical candidates.

San Diego, California, United States

• Investigated neuronal circuits supporting cognitive function in vivo.
• Developed new research directions and technologies utilizing chemo- and optogenetics.
• Initiated collaborations with leading laboratories at world renowned institutions.
• Supervised several technicians, trained PhD student and managed mouse colony.
• Contributed to research into mechanisms of epilepsy.

Zurich, Switzerland

Spearheaded and managed innovative collaboration with bioinformatician and proteomics expert to explore novel data sets, contextualize them and understand their significance.

Zurich, Switzerland

• Examined molecular factors determining cognitive performance in a collaboration with three world-renowned laboratories as part of an HFSP grant.
• Generated new conditional transgenic mouse lines using cutting edge technology. Managed mouse colony of over 15 different transgenic lines with the assistance of direct report.
• Conducted biochemical, molecular and behavioral assays to examine phenotypes in mouse models.
• Contributed to research into mechanisms of ischemia and schizophrenia.

Munich, Bavaria, Germany

• Researched the molecular mechanisms of Down Syndrome with focus on the kinase Dyrk1A.
• Acquired solid laboratory skill set at one of Europe’s top research institutions.

Phd, Neuroscience

Ms, Biology

Bs, Biomedical Science