Karsten Baumgärtel Email and Phone Number
Strategic and innovative leader that enjoys navigating both the bigger scope and intricate details of research endeavors. Specialized in expanding and advancing R&D portfolios by leveraging his expertise in early drug discovery and translational biology and his ability to work seamlessly with business development, identify new opportunities, and form alliances. Characterized by an unwavering dedication to utilizing scientific knowledge for the betterment of patient care and a profound desire to make a tangible difference in people's health.
Refactor Biosciences
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Co-FounderRefactor Biosciences Jul 2024 - Present -
OwnerAmplio Consulting Llc Jan 2024 - PresentOffering companies and patient groups consulting services within my areas of expertise.
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Scientific Research CoordinatorAlagille Syndrome Alliance Jan 2024 - Present -
Director, Translational BiologyTravere Therapeutics Apr 2022 - Dec 2023Pipeline Progression and Expansion, Project Lead• Led a multi-center discovery program through screening activities on multiple different assay platforms and hit triaging.• Designed research strategy to direct and streamline external innovation efforts.• Developed and presented critical diligence insights to senior management to support in-licensing and acquisition go/no-go decisions.• Established and managed collaborations with top-tier academic institutions for existing and new research directions.• Developed and implemented translational strategies for programs in hepatology, and inborn errors of metabolism. -
Associate Director, Translational BiologyTravere Therapeutics Apr 2020 - Apr 2022San Diego, California, United States• Worked closely with BD to assess pipeline expansion opportunities in nephrology, hepatology, and neurology.• Helped transition a newly acquired program to Travere.• Led a multi-center discovery program in the development of assay platforms and disease relevant cellular models of multiple different levels of complexity. -
Principal ScientistTravere Therapeutics May 2018 - Apr 2020San Diego, California, United States• Championed unique collaborative research agreement with the National Center for Advancing Translational Sciences (NCATS) and served as the alliance manager and scientific lead. Generated mechanistic insights into disease pathogenesis to support selection of appropriate screening assays and translational models.• Identified pipeline expansion opportunities in neurology, nephrology and hepatology.• Spearheaded exploration and due diligence of new modalities with focus on Neurology and Hepatology.• Provided preclinical research support for neurological and nephrological indications in clinical programs and regulatory filings.• Helped develop and implement translational strategies for program in neurology.
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Group Leader, Target Validation, And Project LeadDart Neuroscience Llc Sep 2012 - Feb 2018San Diego, California, United States• Spearheaded and led a multidisciplinary drug discovery program within neurology.• Optimized and streamlined target discovery and prioritization by leading a cross-functional project team.• Collaborated with Bioinformatics to develop custom database tools for knowledge capture and target prioritization.• Successfully identified and validated novel targets, promoting several to project status.• Established mechanisms of action (MOA) for target genes related to the indication of interest.• Explored new indications compatible with existing clinical candidates.• Pioneered new technologies and approaches, including virally delivered shRNA.• Served as an IACUC member and DEA representative.
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Postdoctoral ResearcherThe Scripps Research Institute Aug 2008 - Sep 2012San Diego, California, United StatesInvestigated neuronal circuits supporting cognitive function in vivo. • Developed new research directions and technologies utilizing chemo- and optogenetics.• Initiated collaborations with leading laboratories at world renowned institutions. • Supervised several technicians, trained PhD student and managed mouse colony.• Contributed to research into mechanisms of epilepsy. -
Postdoctoral ResearcherUniversity Of Zurich Jul 2007 - Jun 2008Zurich, SwitzerlandSpearheaded and managed innovative collaboration with bioinformatician and proteomics expert to explore novel data sets, contextualize them and understand their significance. -
Phd StudentEth Zurich Mar 2003 - Jun 2007Zurich, SwitzerlandExamined molecular factors determining cognitive performance in a collaboration with three world-renowned laboratories as part of an HFSP grant.• Generated new conditional transgenic mouse lines using cutting edge technology. Managed mouse colony of over 15 different transgenic lines with the assistance of direct report.• Conducted biochemical, molecular and behavioral assays to examine phenotypes in mouse models.• Contributed to research into mechanisms of ischemia and schizophrenia. -
Masters StudentMax-Planck Institute For Psychiatry May 2001 - Apr 2002Munich, Bavaria, GermanyResearched the molecular mechanisms of Down Syndrome with focus on the kinase Dyrk1A. • Acquired solid laboratory skill set at one of Europe’s top research institutions.
Karsten Baumgärtel Education Details
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Neuroscience -
Biomedical Science
Frequently Asked Questions about Karsten Baumgärtel
What company does Karsten Baumgärtel work for?
Karsten Baumgärtel works for Refactor Biosciences
What is Karsten Baumgärtel's role at the current company?
Karsten Baumgärtel's current role is Discovery & Translational Biology I Neuroscience & Rare Disease I Innovative Scientific Leadership I Strategy Development & Implementation I Collaborative Research I Team Building & Mentoring.
What schools did Karsten Baumgärtel attend?
Karsten Baumgärtel attended Eth Zürich, Ludwig-Maximilians-Universität München, University Of Technology Sydney.
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