Kashif Sadiq Email and Phone Number
Kashif Sadiq work email
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I am a biophysics researcher and entrepreneur. My research interests are in combining theoretical and computational physics methods with artificial intelligence to understand high-dimensional chemical and biological processes that span several spatiotemporal scales. I am also passionate to build on this research to develop practical applications in personalised medicine, drug discovery, clinical decision support and synthetic virology/nanotechnology. I bring extensive experience in computational biophysics/biochemistry and high-performance computing (HPC) in all-atom molecular dynamics (MD) simulations, coarse-grained MD simulations, chemical reaction kinetics, reaction diffusion approaches and machine/deep learning methods. Experience includes GPCR, HIV protein and RNA modelling, autocatalysis, conformational kinetics, macromolecular structure prediction, virus morphology, rational drug design, self-assembly of soft condensed bio-matter, binding free energy and kinetics methods, advanced sampling techniques in MD, prediction of resistance mutations, personalised medicine from genotypic assays and de novo protein design.
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Founder & CeoDenovai Biotech Feb 2023 - PresentRehovot, Center District, IsraelFounder and CEO of DenovAI Biotech. At DenovAI, we believe that humanity is on the cusp of a protein design revolution that stands to transform human health and the world around us. And we are passionate about building the platform and team that will lead us there. Harnessing the power of artificial intelligence and computational molecular biophysics we are developing foundational technology platforms that can design proteins de novo - completely from scratch. And we are at the start of an exciting journey to design next generation therapeutics like high-affinity antibodies, small protein and peptide biologics, and diagnostic reporters - all tailored to bind to their specific targets. As well as novel proteins and enzymes for the sustainable food, chemical and biomaterial industries. To find out more, please visit: https://denovai.com -
Biophysicist And Data ScientistEmbl Nov 2020 - Oct 2023Heidelberg, Baden-Württemberg, GermanyUsing AI-based approaches that build on the richness of available structural data, we are developing novel frameworks for de novo protein design [1]. These approaches allow us to explore sequence space well beyond that explored by evolution and design new proteins that have never existed before in Nature. Such approaches can be tailored to design proteins that can bind strongly to other proteins, self-assemble into multimers, and even change conformation in different settings. [1] Jendrusch, M., Korbel, J. O., & Sadiq, S. K. (2021) bioRxiv. AlphaDesign: A de novo protein design framework based on AlphaFold. https://doi.org/10.1101/2021.10.11.463937https://sadiqresearch.com -
Senior Research FellowHeidelberg Institute For Theoretical Studies (Hits) Mar 2016 - Oct 2020Heidelberg Area, Germany• Principal investigator of Volkswagen Foundation grant – modelling multiscale physics of sub-cellular polymer-protein condensates, capsid assembly and retroviral infectivity.• Senior research fellow in EU-collaboration: Kinetics for drug discovery (k4dd.eu). Developed enhanced sampling methods in all-atom molecular dynamics (MD) and Brownian dynamics (BD) for drug-protein binding kinetics. -
Amfar Mathilde Krim FellowUniversitat Pompeu Fabra - Upf Oct 2013 - Feb 2016BarcelonaPrincipal investigator (PI) and Mathilde Krim Fellow on American Foundation for AIDS Research (amfAR) grant. Developed a computational drug-discovery pipeline including high-throughput virtual screening, all-atom MD and coarse-grained reaction diffusion. Led collaboration with experimental virologists, biochemists and medicinal chemists exploring novel HIV interference pathways for AIDS eradication. -
Founder And DirectorScience English Editors Ltd Sep 2012 - Feb 2016London, United KingdomFounded and directed Science English Editors (SEE), a company which helps scientists and medical professionals from all around the world to overcome any linguistic barriers in written English that would otherwise impair their research being published.
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Postdoctoral Research FellowUniversitat Pompeu Fabra Jan 2009 - Aug 2012Barcelona Area, SpainI won a Marie-Curie Intra European Fellowship Award. Developed high-throughput MD methods for protein folding kinetics on a distributed GPU computing architecture (GPUGRID.net). -
Postdoctoral Research FellowUniversity College London Oct 2007 - Dec 2008 -
Private Tutor: Mathematics, Physics, Chemistry, BiologyOxford Cambridge Tutors Jul 2003 - Apr 2004London, United Kingdom
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English And Business English TutorDaqing Oil Jan 2003 - Mar 2003Daqing, Heilongjiang, China
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Software DeveloperClarins Uk Aug 2001 - Apr 2002London, United Kingdom -
Software DeveloperIbm Jul 1998 - Sep 1998Bedfont Lakes, London -
Pre-University Employee: It And Technical SupportIbm Sep 1996 - Jun 1997Bedfont Lakes, London
Kashif Sadiq Skills
Kashif Sadiq Education Details
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Natural Sciences
Frequently Asked Questions about Kashif Sadiq
What company does Kashif Sadiq work for?
Kashif Sadiq works for Denovai Biotech
What is Kashif Sadiq's role at the current company?
Kashif Sadiq's current role is Founder & CEO, DenovAI Biotech: Biophysicist, Entrepreneur.
What is Kashif Sadiq's email address?
Kashif Sadiq's email address is sy****@****ail.com
What schools did Kashif Sadiq attend?
Kashif Sadiq attended University Of Cambridge, Ucl.
What are some of Kashif Sadiq's interests?
Kashif Sadiq has interest in Science And Technology, Disaster And Humanitarian Relief.
What skills is Kashif Sadiq known for?
Kashif Sadiq has skills like Physics, Bioinformatics, Computational Biology, Protein Chemistry, Molecular Dynamics, Molecular Modeling, Molecular Biology, Biochemistry, Systems Biology, Cell Biology, Life Sciences, Mentoring.
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