Kate Pinnion Brown Email & Phone Number

Cambridge, England, United Kingdom

Cambridge, England, United Kingdom

Molecular techniques and histology

Cambridge, United Kingdom

• UK pathology contact for all peripheral histology in Cardiovascular & Metabolism with specialism in liver, kidney and gastrointestinal.
• Identify and implement new technologies to advance the investigative and mechanistic toolbox for pathology support to key projects
• Running of IHC lab. Point of contact for development of new pathology and histology labs.
• Target champion. Project oversight role driving target through the pipeline.
• Experience collaborating with and… Show more
• Experience collaborating with and assessing potential external laboratory partners

Cambridge, United Kingdom

• Key pathology contact for Respiratory & Inflammation disease area & project support including target identification, model validation & safety liability.
• Optimisation of IHC and staining of novel targets on fixed and frozen tissue.
• Scientific input into study design for studies requiring pathology support
• Use of image analysis software to quantify & grade IHC or tinctorial staining on animal models or human disease samples. •
• All routine histology; sampling… Show more
• All routine histology; sampling, processing, sectioning and tinctorial stains.

Wythenshawe Hospital

• Deliver on contracts for pharmaceutical companies; including histological biopsy outputs, staining of biological samples (time, cost, manage resource) with counts & interpretation.
• Running IHC lab, co-ordinating the Histology Samples Bank and management of technicians and students, including coaching new skills, techniques and optimisation.
• Focus on Respiratory, including COPD and asthma.
• Overseeing team in wet tissue collection (from hospital), liaising with hospital… Show more
• Overseeing team in wet tissue collection (from hospital), liaising with hospital depts.
• Part of team that co-ordinated the relocation of lab to another premise.

Safety Assessment, Loughborough, Leicestershire

• Investigative IHC (including fluorescent) from concept to assay and interpretation to answer project biological and mechanistic questions. Considered tissue sections alongside clinically relevant human samples or in.
• Management and supervision of students (PhD and MD) and technicians. This often involves training of IHC, fundamentals of assay design, slide reading and interpretation.
• Skilled handling of human… Show more
• Skilled handling of human tissues; tumour resection margin or lung explants.
• Presented findings at national & international conferences (including ERS and BTS) as well as reporting projects at global internal meetings as well as publishing scientific research.
• Responsibility of key contact for several external collaborations and cross-departmental projects. This frequently involved visiting other sites and discussing research ideas.

Safety Assessment, Loughborough, Leicestershire

• Solid foundation in routine histological techniques including necropsy, histology processing, sectioning, tinctorial staining and IHC (both manual and automated) of both animal and human tissue. Small rodent organs.

Belton, Leicestershire

• Cell culture of hybridoma lines to produce monoclonal antibody.
• ‘Clean room’ sterile working and rigorous QC behaviour for retail products.

York, United Kingdom

• Developed and refined ELISA assays for cat, dog and horse Ig titre testing.
• Worked independently in a small team.

Boxford, Suffolk

• biochemical QC tests and HPCL solvent extraction to monitor mould.

Phd, Pathology

"Histopathology of diffuse lung parenchyma epithelial metaplasia in COPD" • Molecular characterisation of epithelial cells, surrounding.

Postgraduate Certificate, Lung Pathology, Pass

Msc, Biomedical Science

“Development and Application of Phage-Derived Antibodies for the Immunocytochemical Characterisation of Bronchiolitis” using rat disease.

Bsc, Biochemistry