Carlos Eduardo Madureira Trufen, M.Sc. Email and Phone Number
Strong background in mathematics, science, and technologyProven track record of developing and implementing bioinformatics pipelines for large-scale transcriptome experimentsExcellent programming skills in R and Python, with experience in Linux systems and parallel processingStrong understanding of molecular biology, genetics, and genomics, with experience in data analysis and interpretationAble to effectively communicate complex scientific concepts and results to both technical and non-technical audiences.Designed and implemented pipelines for analyzing bulk and single-cell RNA-Seq data, including quality control, batch effect removal, and differential expression analysisConducted data analysis and interpretation, including differential expression analysis, coexpression analysis, network/systems biology, pathway enrichment, statistical analyses, and visualization
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BioinformaticianPrevorLiège, Wal, Be
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Research Engineer - BioinformaticianPrevor Jan 2024 - PresentLiège, Walloon Region, BelgiumResearching potential molecular targets in multiple sclerosis.
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Recognized Peer ReviewerElsevier Jun 2020 - Feb 2024Reviewed scientific papers, including confidential comments to editors and comments to authors. -
Phd StudentInstitute Of Molecular Genetics Of The Czech Academy Of Sciences May 2022 - Jan 2024Prague, CzechiaProject: Integration of phenotyping and functional genomic data -
Bioinformatics Research AssistantInstitute Of Molecular Genetics Of The Czech Academy Of Sciences Oct 2019 - May 2022Prahe, Czech RepublicDevelopment of pipelines to analyze both bulk and single-cell RNA-Seq data. The bulk RNA-Seq pipeline includes quality control, batch effect removal, differential expression analysis, ORA, GSEA, and deconvolution analysis. The scRNA-Seq pipeline includes doublet removal, feature selection, clustering, annotation, differential expression analysis, cell cycle assignment, and trajectory analysis.Performed motif discovery from CHIP-Seq data.Participated in the preparation of grant proposals, scientific manuscripts, and reviews. Use of statistical analysis (multiple factor analysis, correlation) and data visualization.Programming in the R (caret, mlr, XGBoost) and Python (TensorFlow, Keras) languages, using Linux systems, and CPU/GPU parallelism. Automation of routine tasks (including emailing).
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BioinformaticianGenieus Genomics Nov 2021 - Dec 2021Analyzed bulk RNA-Seq datasets related to neurodegenerative disease, searching for potential marker lncRNAs.Investigated potential miRNA-lncRNA binding sites. -
BioinformaticianCentd Oct 2017 - Oct 2019São Paulo Area, BrazilDesigned, developed, and implemented a custom pipeline to pre-process and analyze experimental data produced by large-scale transcriptome experiments (RNA-Seq) aiming to discover new molecular targets, taking part in the data analysis and interpretation of results (cell signaling, immunology, and cancer). Pre-processing had removal of phi X sequence, removal of adapters, sequence alignment, and batch effect correction. The analyses included differential expression, coexpression analysis, network/systems biology, pathway enrichment, statistical analyses (PCA analysis, linear regression), and visualization.Programmed in R and Python, optimizing code, implemented in Linux systems using multiprocessor cluster systems for parallel processing.Employment of tools to predict viral epitope peptide and protein structure. -
Research Support TechnicianInstituto Butantan Sep 2010 - Oct 2019São Paulo E Região, BrasilDry lab:Designed, pre-processed, analyzed, and interpreted NGS-based experiment (RNA-Seq) to optimize biotechnology production. The analyses included differential expression, coexpression, and pathway enrichment, with programming in R language and Linux systems. Wet lab:Prepared solutions, controlled reagents stock, dosed bacterial polysaccharides, handled autoclave, pH-meter, and spectrophotometer.Performed molecular biology experiments (RNA enrichment, qPCR). -
Research Support AgentInstituto Adolfo Lutz Dec 2006 - Sep 2010Av. Dr. Arnaldo, 355, Cerqueira Cesar, São PauloPrepared culture media, handled autoclave and pH-meter; elaborated and approved biosafety and standardized operational procedures (SOPs). -
InternSabesp Jun 2006 - Dec 2006São Paulo E Região, BrasilPerformed hydrobiological analyses, collected samples, applied the Sedgwick-Rafter method, identified algae. -
InternIbt - Instituto De Botânica De São Paulo Jun 2006 - Dec 2006Avenida Miguel Stéfano, 3031, Água Funda, São PauloMonitoring of students by the Botanical Garden. -
InternSesc Itaquera Jan 2004 - Dec 2005Av. Fernando Do Espírito Santo Alves De Mattos, 1000, Itaquera, São PauloActing in Environmental Education, with the development of socio-environmental activities for the local community;
Carlos Eduardo Madureira Trufen, M.Sc. Skills
Carlos Eduardo Madureira Trufen, M.Sc. Education Details
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Bioinformatics -
Bioinformatics -
Mathematics -
Science & Technology
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Biological Sciences
Frequently Asked Questions about Carlos Eduardo Madureira Trufen, M.Sc.
What company does Carlos Eduardo Madureira Trufen, M.Sc. work for?
Carlos Eduardo Madureira Trufen, M.Sc. works for Prevor
What is Carlos Eduardo Madureira Trufen, M.Sc.'s role at the current company?
Carlos Eduardo Madureira Trufen, M.Sc.'s current role is Bioinformatician.
What schools did Carlos Eduardo Madureira Trufen, M.Sc. attend?
Carlos Eduardo Madureira Trufen, M.Sc. attended Vysoká Škola Chemicko-Technologická V Praze, Universidade De São Paulo, Universidade Federal Do Abc - Ufabc, Universidade Federal Do Abc - Ufabc, Universidade São Judas Tadeu.
What skills is Carlos Eduardo Madureira Trufen, M.Sc. known for?
Carlos Eduardo Madureira Trufen, M.Sc. has skills like R, Git, Linux, Microsoft Powerpoint, Matlab, Transcriptomics, Pesquisa, Microsoft Office, Biologia Molecular, Latex, Microsoft Word, Trabalho Em Equipe.
Who are Carlos Eduardo Madureira Trufen, M.Sc.'s colleagues?
Carlos Eduardo Madureira Trufen, M.Sc.'s colleagues are Paulo Henrique Alves Da Silva, Angélique Dachy, Kushala Gajengi, Camille Requena, Zénaïde Horsin, Abderrahmane Laidli, Regina Müller.
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