The complex metabolic networks of the cell are endlessly fascinating, but I am most intrigued by the set of systemic changes that occur during the transformation into malignant cancer cells. The whole-scale remodelling of metabolic pathways that must take place to sustain the proliferative phenotype, with all the regulation and dysregulation required thereof, is a compelling field of study where many unknowns remain.My experience is in cancer metabolism using gas chromatography mass spectrometry (GC-MS) as the main analytical tool. I also have some experience researching dysregulated metabolism in other contexts, such as diabetes and inflammation.