Kellye Kirkbride Email & Phone Number

Huntsville, Alabama, United States

Responsible for the overseeing the implementation of the Quality Management System & managing the quality team.

Huntsville, Alabama Area

Responsible for implementation of a GCLP Quality System.

Franklin, Tennessee

Franklin, Tennessee

Co-team leader for the development and design of the ChemoINTEL platform, an automated, multiplexed, high-content image-based human cancer in vitro diagnostic. Responsible for study plan design and execution, including data analysis, interpretation and summation. Part of the management team that oversees the training and projects of laboratory staff. Implement laboratory process improvements. Operate in a cGxP environment, including developing instrument quality control, writing and implementing SOPs, maintenance logs and CAPAs.

Franklin, Tn

Co-project lead on the validation of the ChemoINTEL platform.

Franklin, Tennessee

Member of a biopharmaceutical company focused on the discovery of small-molecule drugs that target WNT and Sonic Hedgehog (SHH) signaling, pathways fundamental to cancer and tissue regeneration. Optimizing efficient high-throughput in vitro assays to test compound efficacy.

Department Of Biomedical Engineering

Advisors: Dr. Todd Giorgio and Dr. Craig DuvallProject Title: Determining the in vivo efficacy of nanocarriers for drug delivery to tumors.Responsibilities: Preform breast cancer animal model studies to characterize the delivery of siRNA by targeted nanocarriers to tumor tissue. Prepared IACUC and IRB approval forms. Responsible for grant proposal development and manuscript writing.

Nashville, Tennessee

Laboratory of Dr. Alissa WeaverProject Title: Determining the Role of the cytoskeletal protein, cortactin, in protein trafficking.Summary: Gained extensive experience and skills in cancer and cell biology techniques and approaches. Completed a team research project determining the cause of protein trafficking defects in genetically manipulated cancer cells. Optimized the experimental design and analysis of critical microscopy-based experiments. Used high-throughput imaging to preliminarily determine cancer cell response to chemotherapeutics. Assisted physician scientists in establishing an in vivo model to examine chemotherapeutic response of human head and neck patient cancer cells. Authored a review article of the molecular contributions of cortactin to cell behavior.

Was a full-time instructor teaching General Biology I and General Microbiology. Was responsible for all course preparation and educational materials for these courses.

Durham, North Carolina

Laboratory of Gerard C Blobe, MD, PhDDissertation Title: Elucidating the Role of the Transforming Growth Factor-beta Type III Receptor in Bone Morphogenetic Protein Signaling.Summary: Performed biochemical and cancer research understanding ligand and receptor interactions. Experienced in several different techniques- including radiolabelling proteins, binding & crosslinking assays, immunoblotting, immunohistochemistry, RT-PCR, soft agar assay, proliferation (thymidine labelling), animal modeling (breast cancer using 4T1 cells and subcutaneous tumor growth using colon cancer cells) and luciferase assays.

Bloomington, Indiana Area

Laboratory of Wayne Forrester, PhDTitle: Integration of an active receptor for screen identifying downstream components of cam-1 pathway.

Phd, Molecular Cancer Biology

Activities and Societies: Graduate & Professional Student Council- Departmental Representative (2002-2004) & Executive.

B.S., Biology, 4.92

Activities and Societies: Phi Beta Kappa, Mortar Board, Student Athletic Board- President (2000-2001) & Director (1999-2000)Graduated.