Phd Candidate
Hong Kong, Pokfulam, Hk
First-authored works are decently cited. (https://scholar.google.com/citations?user=scNSIAcAAAAJ&hl=en)The main PhD project, Linnorm, is the top performer in the following independent review: Tian, L., et al. Nature Methods 16, 479–487 (2019). Preprint: https://doi.org/10.1101/433102 Subscription: https://doi.org/10.1038/s41592-019-0425-8.It is one of the recommended tools on 10xGenomics and SevenBridges. (https://www.10xgenomics.com/resources/analysis-guides/single-cell-rna-seq-data-normalization) (https://www.sevenbridges.com/highly-customizable-multi-sample-single-cell-rna-seq-pipeline-on-the-cgc/)Development of NGS sequencing data analysis pipeline.Statistical/Machine Learning algorithm review and development.Analysis of biological data.Publications: - Yip, S. H., Wang, P., Kocher, J. P. A., Sham, P. C., & Wang, J. (2017). Linnorm: improved statistical analysis for single cell RNA-seq expression data. Nucleic acids research, 45(22), e179-e179. - Yip, S. H., Sham, P. C., & Wang, J. (2018). Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data. Briefings in bioinformatics. - Jiang, H., Liang, L., Qin, J., Lu, Y., Li, B., Wang, Y., ..., Yip, S. H., ..., & Chen, J. (2016). Functional networks of aging markers in the glomeruli of IgA nephropathy: A new therapeutic opportunity. Oncotarget, 7(23), 33616. - Cheng, T. H., Thompson, D. J., O'Mara, T. A., Painter, J. N., Glubb, D. M., Flach, S., ..., Yip, S. H., ..., & Spurdle, A. B. (2016). Five endometrial cancer risk loci identified through genome-wide association analysis. Nature genetics, 48(6), 667-674. - Gong, B., Li, D., Kusko, R. et al. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome Biol 22, 109 (2021).
