Khaled Jami Email & Phone Number

San Jose, CA, US

Leading characterization of mAb self-association by small-angle X-ray scattering (SAXS) and epitope mapping through hydrogen-deuterium exchange (HDX) mass spectrometry.Completed time-sensitive analytical assays for stability, IND characterization, and clinical in-use studies.Established relationships with CROs to complete external studies and vendors to.

South San Francisco, California, United States

Achieved subject matter expert (SME) through independent study for multi-angle light scattering (SEC-MALS) and evaporative light scattering detection (ELSD) with mixed-mode LC.Performed extensive experiments (cross-linking, SEC-MALS, CE-MS, CE-SDS) to characterize Probody® therapeutics, including platform mAb, ADC, and BsAb modalities.Designed and.

Davis, CA

Investigated proteins associated with ALS and Alzheimer’s disease using structural biology techniques, including solution & solid-state NMR and cross-linking mass spectrometry (XL-MS). Developed and optimized purification strategies using Co/Ni affinity, SEC, and ion-exchange (CEX/AEX), for challenging, aggregation-prone, and low-yielding protein.

Head TA for upper-division organic chemistry (118C), managed enrollment of 800+ students, coordinated exam logistics, and provided instruction and guidance to 15 TAs.

Attained excellent student evaluations (>4/5) for all 10 quarters as a teaching assistant across various chemistry disciplines.- Pharmaceutical Chemistry (CHE 130A)- Analytical Chemistry (CHE 105)- Physical Chemistry (CHE 107B)- Organic Chemistry (CHE 8B, 118A, 118B)- General Chemistry (CHE 2B, 2C)

Thousand Oaks, CA

Quantified BsAb and mAb purity, aggregation by SEC and N-linked glycosylation by HILIC. Meticulously documented procedures and data in an ELN to ensure accuracy and traceability. Enhanced analytical throughput, analyzing 100+ samples per week, improving average data turn-around time from 7 to 3 days.

Los Angeles, CA

Operated a Siemens RDS-112 cyclotron to produce Curie-level radionuclides, performed cGMP radiosynthesis, and QC (GC, LAL endotoxin, radio-TLC, & sterility) of radiopharmaceuticals.

Canoga Park, CA

Isolated and characterized human leukocyte antigen (HLA) genotypes from immortalized B lymphocytes by DNA microarray. Enhanced team output by implementing improvements in cell culture scaling, aseptic technique, and DNA isolation processes.

San Francisco, CA

Engaged in the holistic development, from synthesis to pre-clinical assessment in mice, of positron emission tomography (PET) probes for imaging PD-L1 and the glucocorticoid receptor.Completed the ‘cold’ synthesis of steroid, quinoline, and ribose PET probes, validated efficacy via receptor-ligand binding assays, and quantified biodistribution in.

Doctor Of Philosophy - Phd, Chemistry And Chemical Biology

Designated Emphasis in Biotechnology

Bachelor’S Degree, Chemistry

Igetc/Uc, Liberal Arts