Successfully transitioned from academia to industry through collaboration with the MERCK R&D team, focusing on predicting protein behavior during drug purification.- Extensive utilization of PDB, Alphafold, and UniProt databases via REST API.- Applied homology search and modeling techniques to effectively prepare protein structures.- Significantly enhanced expertise in correcting and optimizing experimental PDB protein structures.- Collaborated with the ChemComp (MOE)… Show more Successfully transitioned from academia to industry through collaboration with the MERCK R&D team, focusing on predicting protein behavior during drug purification.- Extensive utilization of PDB, Alphafold, and UniProt databases via REST API.- Applied homology search and modeling techniques to effectively prepare protein structures.- Significantly enhanced expertise in correcting and optimizing experimental PDB protein structures.- Collaborated with the ChemComp (MOE) developers team to create customized user applications.- Employed machine learning methods, including random forest and regression models, for in-silico predictions. Show less

As a postdoctoral researcher, I worked on diverse projects, including analyzing non-canonical DNA and therapeutic protein structures using ion mobility mass spectrometry. In one project, we observed the compaction of i-motif non-canonical DNA structures during electrospray ionization, detailing the findings in a JASMS publication.In another project, I drove collaboration between an academic lab and MERCK, focusing on therapeutic protein structure analysis. I used a solution… Show more As a postdoctoral researcher, I worked on diverse projects, including analyzing non-canonical DNA and therapeutic protein structures using ion mobility mass spectrometry. In one project, we observed the compaction of i-motif non-canonical DNA structures during electrospray ionization, detailing the findings in a JASMS publication.In another project, I drove collaboration between an academic lab and MERCK, focusing on therapeutic protein structure analysis. I used a solution hydrogen/deuterium exchange and ion mobility mass spectrometry method, uncovering a new ESI ionization mechanism named the "bead ejection mechanism" (BEM). The research was published in JACS Show less

During my PhD thesis, I led an international scientific collaboration with a partner from the MARS500 program, enabling the use of unique biological materials from astronauts. This effort aimed to establish a baseline for urinary proteomics in healthy individuals, providing valuable insights for biomarker discovery.Collaborating with postdoc researchers and an IT specialist, we developed cutting-edge methods for data acquisition and analysis. Specifically, we created an algorithm to… Show more During my PhD thesis, I led an international scientific collaboration with a partner from the MARS500 program, enabling the use of unique biological materials from astronauts. This effort aimed to establish a baseline for urinary proteomics in healthy individuals, providing valuable insights for biomarker discovery.Collaborating with postdoc researchers and an IT specialist, we developed cutting-edge methods for data acquisition and analysis. Specifically, we created an algorithm to automate MS spectra curation and spectral matching. The resulting spectral library, encompassing over 7700 peptides, was published in the Journal of Proteome Research and deposited in the ProteomeXchange Consortium. Show less