Kitty Chui, Ph.D. Email & Phone Number

San Francisco, CA, US

• Assay development of immuno-qPCR add-on product: to develop a generic add-on chemical-conjugated oligonucleotides to lower the detection limits of secreted proteins from multi-cell type organoids such as.
• In vitro cell-based assay development for characterization of human induced pluripotent stem cell iPSC-derived stem cell products.
• Design and validate biomarkers of iPSC-derived cells sold by Tempo Bioscience, such as brain microvascular endothelial cells (BMEC), astrocytes, neurons, microglia, monocytes, macrophages, megakaryocytes, hepatocytes.
• Characterized blood brain barrier (BBB) model using iBMECs with known compound penetration and inhibitors for barrier functions and in vitro drug pharmacological assays such as various formats of antibodies.
• Assay development of 3D 4-cell type hepatic organoid MASH model: inflammation by ELISAs.
• Design for genotype DNA sequencing of custom patient-derived stem cell projects.

2009, 2013-2014, 2015-2016

Sertoli Biology & Reproductive Function/Toxicology Applications:(1) Characterize human primary testicular derived sertoli cells; Sertoli cell product was launched and distributed via Lonza in 2009.(2) Develop in vitro 3-D reproductive toxicology assay platforms using human sertoli cells.Cancer Biology:(3) Preclinical Testing of truncated galectin-3C in.

(1) Reconstruct in vitro skin product AccuSkin used as an alternative test platform for pharmaceutical and/or cosmetic irritancy, toxicological and efficacy test.(2) Expand Xgene's patented technology to construct AccuCornea from human primary corneal epithelial cells and keratocyes to develop pilot alternative platform for Draize test.(3) Assay.

Wilmington, NC, US