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Krishneel Prasad is listed as PHD Candidate at WEHI (Walter and Eliza Hall Institute of Medical Research), a with 712 employees, based in Parkville, Victoria, Australia. AeroLeads shows a matched LinkedIn profile for Krishneel Prasad.
Krishneel Prasad previously worked as Honours at the Jenkins Lab at Wehi (Walter And Eliza Hall Institute Of Medical Research) and CCV Summer Studentship at Cancer Council Victoria. Krishneel Prasad holds Doctor Of Philosophy - Phd, Immunology / Synthetic Biology from University Of Melbourne.
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Our understanding of human biology and ongoing efforts to improve people's health has broughtabout revolutionary changes for the treatment of disease. I am fascinated by the immune system andhow innovations in synthetic biology enables us to promote anti-tumour responses. Recentsuccesses for cellular and gene therapies demonstrate a pivotal shift in our capacity to deliverpersonalised cancer therapies and has motivated me to push the limits of immune cell control for thispurpose. Contributions to multiple research projects and supervision from mentors with diverseexpertise has provided me with unique skillsets and perspectives as a foundation for my ongoinggrowth as a passionate cancer researcher.
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Melbourne, Victoria, Australia
The Jenkins Laboratory has expertise in the preclinical development and validation of novel immunotherapies to treat severe brain cancers. My PhD project explores how the latest cutting-edge innovations for synthetic receptor design can be harnessed to create smarter and safer Chimeric Antigen Receptor T cell therapies to treat High Grade Gliomas.
Melbourne, Victoria, Australia
Completed an Honours year focusing on target validation and development of a novel chimeric antigen receptor (CAR) T cell to treat malignant paediatric and adult gliomas including diffuse midline glioma and glioblastoma. This project was supervised by Associate Professor Misty Jenkins, Dr Ryan Cross and Dr Alex Davenport. Wet lab skills acquired: Primary cell tissue culture • Murine T cell isolation • Flow cytometry • Retroviral/ Lentiviral Transduction • Cloning • Sequencing analysis • Incucyte killing assays • Cytokine bead arrays Dry Lab skills acquired: Patent searching • SnapGene • Prism • Adobe Illustrator • FlowJo • Incucyte and CBA data analysis Demonstrated scientific communication through written text, oral presentations and a poster presented at the WEHI student symposium. A high quality of work was recognised by being awarded the 2022 Colman Speed Award for achieving the highest overall grade in the cohort. This experience was kindly and generously supported by the Strathmore Community Bank Honours Scholarship and the Ann Henderson PhD Scholarship.
Melbourne, Victoria, Australia
Exploring the potential for Chimeric Antigen Receptor T cell approaches, a cutting-edge immunotherapy, to target and kill adult and paediatric brain cancers such as diffuse midline glioma and glioblastoma. The CCV studentship is supporting my early start in the Jenkins lab at WEHI with supervision from Assoc/Prof Misty Jenkins and Dr Ryan Cross. The approaches used include genetic engineering, molecular biology and primary cell tissue culture.
Melbourne, Victoria, Australia
Using CRISPR-Cas13b to silence various tumour driver transcripts, with focus on single-nucleotide variants in multiple cell models under the supervision of Dr Carolyn Shembrey and Dr Mohamed Fareh. Findings supporting the use of reprogrammed Cas13 with single nucleotide precision would be incredibly exciting for improving targeted therapies at the transcriptome level. • Second author on abstract presented at 2021 Lorne Genome Conference (Dec 4th) titled: Towards Cas13-mediated transcriptional repression of tumour drivers with single nucleotide precision. • Selected for the 2021-2022 PMCC Summer Scholarship Program Key techniques include:Tissue Culture • RNA/DNA isolation • Gel Electrophoresis • Sanger Sequencing • Transfections • Transductions • qPCR • Western Blotting • EVOS Imaging • ImageJ • Prism • SnapGene (Introductory) • FACS (Introductory)
Melbourne, Victoria, Australia
Used an omics approach to investigate a novel therapeutic for glycaemic control under the supervision of Dr Magdalene Montgomery. We found a novel relationship between pancreatic alpha and beta cell endocrine activity, with potential to contribute to current NAFLD and diabetes research. Skills learnt include:MIN6 cell culture • GSIS • Insulin ELISAs • Sucrose gradient ultracentrifugation • LC-MS/MS sample preparation/ data analysis • Lipidomics • Proteomics • bioinformatics • Western Blotting • Software (MSDial •Perseus • ImageJ • Prism) • scientific report writing
Victoria, Australia
Used CRISPR/Cas9 technology to investigate new drug targets against platinum resistant Small Cell Lung Cancer under the supervision of Dr Daniel Gough. Techniques learnt include: Transduction • Transfection • Arrayed CRISPR Screens • Cell passaging/ maintenance (adherent/ non-adherent) • (q)PCRs • Gel electrophoresis • Western Blotting • Nucleic acid extractions • Data analysis • Technology operation
Victoria, Australia
Provide 1-on-1 as well as small group tuition covering VCE subjects including Biology and Maths Methods. Have helped students realise their true capabilities within high school studies through emphasis on application and problem solving. Overall goal to help students become more confident with themselves and appreciate the scope linked to subjects taught.
Victoria, Australia
Taught a variety of classes of students ranging from year 5 up to year 10. Taught various topics as well as coordinated with parents/students to run information meetings and insight to academic opportunities available. Regularly managed selective entry based programs facilitated by the origination. Key skills enhanced: communication, organisation, problem solving & teamwork.
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Samaneh Farashi
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Australia
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Lei Qin
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Melbourne, Victoria, Australia
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Joan Curtis
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Greater Melbourne Area, Australia
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Belinda Lee
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Greater Melbourne Area, Australia
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Kate Sutherland
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Greater Melbourne Area, Australia
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Jane Murphy
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Ivanhoe East, Victoria, Australia
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Davide Vespasiani
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Parkville, Victoria, Australia
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Laura Corso
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Melbourne, Victoria, Australia
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Tony Hodder
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Ocean Grove, Victoria, Australia
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Tanya Balashova
Colleague at Wehi (Walter And Eliza Hall Institute Of Medical Research)Greater Brisbane Area, Australia
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The PhD project aims to develop synthetic gene circuits to engineer smarter, safer Chimeric Antigen Receptor T cell therapies.
Grade: First Class Honours • Colman Speed Award • Strathmore Community Bank Honours Scholarship • Ann Henderson PhD Scholarship
• Deans Honours List: Level 2 (2020) • Leaders in Communities Award (2021)
Activities and Societies: Recruiter for school Relay for Life Team: assisted in organising and fundraising Awards: • Leadership Potential.
Quick answers generated from the profile data available on this page.
Krishneel Prasad works for WEHI (Walter and Eliza Hall Institute of Medical Research).
Krishneel Prasad is listed as PHD Candidate at WEHI (Walter and Eliza Hall Institute of Medical Research).
Krishneel Prasad is based in Parkville, Victoria, Australia while working with WEHI (Walter and Eliza Hall Institute of Medical Research).
Krishneel Prasad has worked for Wehi (Walter And Eliza Hall Institute Of Medical Research), Cancer Council Victoria, Peter Maccallum Cancer Centre, University Of Melbourne, and Hudson Institute Of Medical Research.
Krishneel Prasad's colleagues at WEHI (Walter and Eliza Hall Institute of Medical Research) include Samaneh Farashi, Lei Qin, Joan Curtis, Belinda Lee, and Kate Sutherland.
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Krishneel Prasad holds Doctor Of Philosophy - Phd, Immunology / Synthetic Biology from University Of Melbourne.
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