Kuda Mhandire Email & Phone Number

Chapel Hill, Nc, Us

Maryland, United States

o Manage clinical genomic testing pipelines to achieve high-quality diagnostic testing and interpretation.o Analyze real-world data from electronic health records and publicly available databases for evidence to evaluate genetic epidemiology trends.o Lead ACMG-guided genetic variant curation processes in whole exome/genome analysis, neurodevelopmental, metabolic, and rare disorders using ACMG guidelineso Maintain compliance with FDA Oversight and Regulation of lab-developed tests o Conduct complex scientific literature reviews, bioinformatics and data analysis to identify critical evidence to support clinical interpretation of genetic variants.

Buffalo, New York, United States

o Led the design and development of studies to identify therapeutic targets to reduce GvHD in stem-cell therapy of blood disorders and hematological cancers o Spearheaded the writing, reviewing, and amending of regulatory (IRB) submissionso Conducted flow cytometry and RNA sequencing data analysis o Co-authored grant applications, slide decks for weekly scientific presentations, and manuscripts for publication.

Cape Town, Western Cape, South Africa

o Led a matrix team of multi-functional units to design studies, write protocols and regulatory compliance submissions, and collect data in multicenter studies to describe the genetic epidemiology, pharmacogenetics, and immunogenetics of understudied African populationso Led the surveillance of infectious diseases, including HIV, TB, CMV, HPV, and HBV, and their clinical and demographic correlates in phase 3b ART clinical trial participants o Coordinated the aggregation and analysis of disparate real-world data from patient-reported outcomes and electronic health records to ensure fitting inclusion/exclusion criteria eligibility and safeguard data quality in clinical trialso Led and collaborated to undertake the design and data analysis of a study of immunogenetic associates of T-cell responses to attenuated BCG and candidate subunit vaccines in pediatric TB patientso Managed clinical trial site adverse events monitoring, project management, and staff training o Conducted statistical analysis, including regression analyses, survival analysis, meta-analysis, Mendelian randomization, etc. (R, Python, SPSS, STATA, PLINK)

Master'S Degree, Human Genetics

Ph.D., Infectious Disease Epidemiology

Epidemiology of infectious diseases and the host genetic determinants of transmission, disease course, and treatment outcomes.