Kyle Backman Email & Phone Number

San Diego, CA, US

South San Francisco, California, United States

A member of the In-Vivo Pharmacology team. Working to understand the PK/PD of neurological treatments.Conducted two 14-day mouse drug studies with cohorts up to 144 subjects, focusing on detailed and rigorous data collection and analysis.Performed enzyme-linked immunosorbent assays (ELISAs) to support various pharmacological research initiatives.Entrusted.

Cambridge, Massachusetts, United States

• Researching independently as well as heavily assisting on numerous rodent research projects near publication in the Biomedical engineering oriented Jasano Laboratory.
• Actively lead a research study using a novel model of rodent self-administration in rodents to expand understanding of drug addiction withdrawal.
• Dosing of various agents was conducted through multiple routes (IV,IP,SC) followed by tissue collection.
• Innovated the lab’s IACUC protocols and methods for optimized experiments.
• Liaison between the lab and MIT’s Department of comparative medicine, EHS, CAC and DEA.
• Crafted and ran a research pipeline utilizing in-vitro surgeries, animal behavior, fMRI imaging, histology andconfocal imaging, utilizing Benchling for documentation.

Cambridge, Massachusetts, United States

A member of Dr. Jasanoff’s biological engineering and neuroscience laboratory

Cambridge, Massachusetts, United States

• First hire of the mRNA synthesis and design team of the HelixNano startup ($45mm Series A). Developed strategies for improving mRNA science and helped to recruit to the team.
• Conducted mRNA Synthesis for multiple vaccine studies and molecular technology.
• Assisted in cell and tissue based protein/antibody extraction and analysis through both ELISA and western blot.
• Tested unique nucleotide chemistry for optimal transcription, expression, and immune tolerability through both celland gel based assays.
• Optimized the scale-up of mRNA transcription and puri cation via qPCR, bead-based, resin-based and fPLCmethodologies, increasing puri ed mRNA yield by over 50%.
• Responsible for lab management, CRO liaison, ensuring the partnership between teams was highly productive, aswell as shared laboratory equipment was upkept. Recorded data and shared updates via ELN and Benchling.

Cambridge, Massachusetts

• Joined the Molecular biology team at Moderna therapeutics and was provided with an independent research project that led to a thorough presentation to the entire team and generated new ideas. Learned to utilize.
• Experimented in early-stage R&D of mRNA translation modi cation.
• Worked alongside experts in the eld of RNA engineering and computational modeling to design and test noveltherapeutics.
• Executed various mammalian cell transfections and analysis of mRNA binding protein constructs against theirtargets, observing a massive decrease in mRNA deterioration.
• Performed multiple Next-Generation-Sequencing (NGS), protein extraction and western blot experiments.

Phoenix, Arizona

Undergraduate molecular & cellular research internship within Dr. DiStefano’s laboratory. Focused on liver fibrosis research.

Scottsdale, Arizona

Technology company focused on storm water filtration using a polymer-based sponge to absorb oils, metals, and bacteria. My job responsibilities included Biochemical data analysis, data management, and marketing.

Tempe, Arizona

Undergraduate Research at ASU within Dr. Foster Olive’s laboratory. Studying the neurochemical and neuropharmacological basis of drug addiction using rodent models.

Maynard, Massachusetts

Bachelor Of Science - Bs, Neuroscience

Activities and Societies: Vice President of NeuroWaves and a member of the Biomedical Science and Genetics Club. Cum Laude, ASU Academic.

Bachelor Of Science - Bs, Biology

Activities and Societies: Vice-President of NeuroWaves (Medical Neuroscience organization), Member of National Society of Collegiate.

Education record