Kyle Tsang Email & Phone Number

Toronto, Ontario, Canada

• Lead analyst for the Canadian Strategy for Cancer Control project gathering data submissions from jurisdictions and health system partners to create visualizations for a public reporting cancer tool
• Analytical lead for a breast cancer screening indicator refresh to measure participation rates, time to diagnosis, positive predictive value, etc. across Canadian jurisdictions
• Lead meetings with working group members and jurisdictional leads to validate methodologies, answer inquiries, and assess project outcomes

Toronto, Canada Area

• Lead key analytic research projects to better understand clinical outcomes following standard practice of care for breast, cervical, and colon cancer screening programs
• Designed and developed dashboards to monitor and evaluate Ontario's cervical and lung cancer screening programs during COVID-19
• Created several reports on the current state of various cancer diseases by analyzing health utilization data after cleaning and merging data from 9 healthcare databases to understand disease pathway concordance
• Methods include hypothesis testing, logistic regression, propensity score matching, pivot tables, Cox regression modelling in SAS
• Analytic support for the Disease Pathway Management team on the pathway concordance project by producing descriptive statistics on demographic and utilization data for patients with colorectal cancer, as well as.
• Analytic support for the Models of Care team to determine the percentage of survivors from the cancer system to a transitioned state and their interaction with oncologists

Toronto, Canada Area

• Established an investment management framework to strategically leverage and manage ehealth assets to advance the Ministry's policy objectives operating in cross-functional project teams to facilitate stakeholder.
• Collaborated with 3rd party consultants to validate the branch's existing capacity assessment framework in terms of the business and ehealth capabilities of organizations in Ontario to fully realize a successful.
• Managed the benefits realization portfolio to help drive a pragmatic approach in measuring the benefits from ehealth investments to ensure value for money, appropriate stakeholder outreach, and an iterative improvement.
• Researched legislation, health policy recommendations, and academic papers to assist in the development of the operational plan for our branch that manages $1.2 billion in various ehealth portfolios
• Provided high-quality support to various analysts at our branch with activities including: reviewing business cases, preparing executive summaries, developing presentations, facilitating stakeholder meetings, and.

Toronto, Canada Area

• Worked closely with a surgical resident to analyze physiological monitoring data of surgeons while in the operating room collected with BioPac software
• Applied cleaning and smoothing techniques on electrocardiogram (ECG) data, respiration data, and electrodermal activity data based on standards in literature
• Compared physician-identified perceived stressful moments with baseline physiological monitoring data in terms of heart rate variability, respiration rate changes, and galvanic skin response
• Developed the methodological and analytical piece for the surgical resident’s conference abstracts and publications regarding surgeon tress in the operating room

Lexington, Massachusetts

• Discovered methods to implement patient context extraction methods from current EMRs using Imprivata’s OneSign single sign on technology
• Used LEADTOOLS SDK CCOW manager as a method to listen to Clinical Context Object Workgroup (CCOW) messages
• Developed interface applications that use Health Level 7 (HL7) standards to intercept Admit Discharge Transfer (ADT) messages that contain patient demographic information
• Learned the current client and server code architecture written in Java, C#, C++, JS, XML, to integrate possible solutions
• Profiled EMRs to extract patient context information will help enhance a potential analytics component that would be introduced with future versions of OneSign

Toronto, Canada Area

• Analyzing sex differences in mouse liver ChIP-Seq data sets gathered from Top2B knockout mice for various transcription factors, histone modification sites, cohesion factors, etc.
• Developing Python and R scripts to evaluate differential binding between genomic peak regions
• Utilizing publicly available genomic tools including Bedtools, UCSC genome browser, STAMP, RSAT, TRAP, GeneMania
• Designing gene regulatory networks in both the liver and pituitary for sex differences in pre and post puberty data sets using machine learning methods

Toronto, Canada Area

• Genetically engineered a DL4-VLR DNA construct used for transfection and subsequent production of a multimeric protein after isolation through the use of dialysis and column chromatography
• Analyzed the DL4-VLR multimeric protein’s affinity towards Notch receptors through a Dual-Reporter Luciferase assay and flow cytometry
• Activated Notch signaling required for early hematopoietic stem cell differentiation into progenitor T cells through the addition of this novel DL4-VLR protein

Cambridge, Massachusetts

• Improved the homing mechanism of human mesenchymal stem cells (hMSCs) towards sites of inflammation by engineering them to express certain protein ligands (PSGL1, SLEX) in their membrane
• Analyzed rolling mechanism of MSCs through video analysis of flow chamber assays in conjunction with endothelial cells
• Performed different assays to evaluate efficacy and properties of transfected cells including Boyden transwell chemotactic assay, flow cytometry, ELISA, flow chamber assay, adhesion assay
• Mastered several biological relevant techniques including aseptic cell culture, SDS-PAGE gel electrophoresis, PBMC and T-cell isolation, DNA amplification, in vivo cell preparation and injection, etc.
• Aided in the process of building a cancer detection therapy device involving the use of aptamers and rolling circle DNA amplification in a microfluidic chamber
• Researched the use of MSCs to manage the effects of graft-versus-host disease and myocardial infarctions

Glasgow, Scotland

• Evaluated the effectiveness and efficiency of encapsulating Candida Antarctica lipase B using bioinspired silicification methods
• Investigated various immobilization methods for biocatalysts to improve enzyme stability
• Modified and measured the activity of enzymes by supporting them onto amorphous silica
• Performed colorimetric assays and ran FTIR spectroscopy to analyze results
• Presented research at U of T’s Undergraduate Engineering Research Day (UnERD) competition and received Best Podium Presenter Award

Toronto, Canada Area

• Analyzed the different proteins and factors (e.g. VEGF, RANKL, etc.) released from apoptotic osteocytes that affect osteoclast formation
• Mastered biological techniques including ELISA, and aseptic cell culture for MLO-Y4 Cells

Toronto, Canada Area

• Taught children and parents basic swimming techniques and water-safety skills ranging from ages 6 months – 12 years old
• Certified in Lifesaving Society standards including National Lifeguard Service, AED responder, Aquatic supervisor training
• Developed strong communication and teamwork skills with aquatic staff on duty in order to prevent water related accidents and the treatment of medical emergencies
• Acquired class management, teaching and leadership skills as a swim instructor emphasizing the need for safety in an aquatic environment

Data Analyst Nanodegree

• Completed Udacity Data Analyst Nanodegree where I worked on key projects to organize data, uncover patterns and insights, perform.

Master Of Health Science, Clinical Engineering, 4.0

Development of an interactive training tool (ITT) to help reduce error rate associated with multiple intravenous (IV) infusion practices.

Bachelor Of Applied Science (B.A.Sc.) In Engineering Science, Biomedical/Medical Engineering