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Kyle Minch is a Principal Scientist at .... He possess expertise in molecular biology, research, systems biology, cell culture, biochemistry and 5 more skills.
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Principal Scientist...Seattle, Wa, Us
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Principal ScientistAvailable Oct 2024 - Present
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Taking A WalkPct Apr 2024 - Present
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Principal ScientistA-Alpha Bio Mar 2023 - PresentSeattle, Washington, United States -
Senior ScientistA-Alpha Bio May 2021 - Mar 2023Seattle, Washington, United States -
Senior ScientistGlobal Health Labs Jul 2020 - May 2021
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Senior ScientistIntellectual Ventures Jan 2019 - Jul 2020Bellevue, WaInnovation, technical, and project lead working on tuberculosis viability monitoring and drug susceptibility testing. Liaison and collaborator with partners at academic institutions, domestic and international non-profits as well as multiple industry partners. Currently leading interdisciplinary project team and regularly communicating project status, risks, and solutions to organization's top managers and stakeholders including top thought and global funding leaders. -
Research ScientistIntellectual Ventures Aug 2017 - Jan 2019 -
Independent Contractor, Research ScientistIntellectual Ventures Jan 2017 - Aug 2017
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Research ScientistIntellectual Ventures Laboratory Aug 2017 - Dec 2018
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Staff ScientistSeattle Biomedical Research Institute Jan 2015 - Jan 2017 -
Postdoctoral Fellow,Seattle Biomedical Research Institute Jul 2012 - Dec 2014Experimental systems biology of Mycobacterium tuberculosis. - Secured Ruth L. Kirchstein training grant fellowship with a competitive renewal for a second year of support. - Coordinated experimental efforts of technicians and undergraduates while developing innovative projects and research directions for the lab: - Developed novel platform for mycobacterial single cell culturing and manipulation on microscope stage. - Collaborated across disciplines to develop computational pipeline to accommodate large-scale imaging data processing requirements - Innovations led to increased throughput and scale of data acquisition, decreasing time from observation to hypothesis testing and generation of results.- Fostered cross-disciplinary collaborations between bench scientists and computational biologists.- Developed and wrote R21 applications on novel approach to live cell imaging of M. tuberculosis (pending review).- Led team generating mutant library of M. tuberculosis strains that critically impacts multi-center, multi-year NIH U-19 projec- Published 2 co-first author papers and 1 additional article during 2.5 year postdoctoral tenure. - Minch, KJ*, Rustad TR*, et al. The DNA binding network of Mycobacterium tuberculosis. Nature Communications. 2015; 9(5829). doi:10.1038/ncomms6829. - Rustad TR*, Minch KJ*, Ma S, et al. Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network. Genome Biology 2014;15(11):502. doi:10.1186/s13059-014-0502-3. - Peterson, EJR. Reiss, DJ, Turkarslan, S, Minch, KJ, Rustad TR, Plaisier, CL, Longabaugh, WJR, Sherman DR, Baliga, NS. A high-resolution network model for global gene regulation in Mycobacterium tuberculosis. Nucleic Acids Res. 2015; 42(18): 11291–11303. Published online 2014 September 17. doi: 10.1093/nar/gku777 -
Predoctoral ResearcherUniversity Of Washington, Molecular And Cellular Biology Program Sep 2007 - Jun 2012Seattle, Wa- National Science Foundation Graduate Research Fellow (2008-2011)- Developed platform to map gene regulatory network of M. tuberculosis. - Published 4 articles during graduate tenure: - Galagan JE, Minch K, Peterson M, et al. The Mycobacterium tuberculosis regulatory network and hypoxia. Nature 2013;499(7457):178-183. doi:10.1038/nature12337. - Rustad TR, Minch KJ, Brabant W, et al. Global analysis of mRNA stability in Mycobacterium tuberculosis. Nucleic Acids Research 2013;41(1):509-517. doi:10.1093/nar/gks1019. - Minch K, Rustad T, Sherman DR. Mycobacterium tuberculosis Growth following Aerobic Expression of the DosR Regulon. Cardona P-J, ed. PLoS ONE 2012;7(4):e35935. doi:10.1371/journal.pone.0035935. - Rustad, T. R., Sherrid, A. M., Minch, K. J. and Sherman, D. R. (2009), Hypoxia: a window into Mycobacterium tuberculosis latency. Cellular Microbiology, 11: 1151–1159. doi: 10.1111/j.1462-5822.2009.01325.x
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Sponsored ResearcherUniversity Of Oxford Sep 2005 - Sep 2006Oxford, United KingdomWorked with multi-disciplinary team of clinician researchers to assess the impact of natural genetic variance on susceptibility to cerebral malaria.
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Sponsored ResearcherBlantyre Malaria Project Jan 2006 - May 2006Blantyre, MalawiProcessed blood and tissue samples from primary clinical studies. Assisted in post-mortem sample collection and processing. Assembled database for meta-analysis of clinical indicators of severe malaria progression.Acted as liaison between on-site and visiting scientists & physicians.
Kyle Minch Skills
Kyle Minch Education Details
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Experimental Systems Biology & Molecular Biology Of Mycobacterium Tuberculosis -
Biology, General
Frequently Asked Questions about Kyle Minch
What company does Kyle Minch work for?
Kyle Minch works for ...
What is Kyle Minch's role at the current company?
Kyle Minch's current role is Principal Scientist.
What is Kyle Minch's email address?
Kyle Minch's email address is ky****@****rch.org
What is Kyle Minch's direct phone number?
Kyle Minch's direct phone number is +120625*****
What schools did Kyle Minch attend?
Kyle Minch attended University Of Washington, Augustana College.
What skills is Kyle Minch known for?
Kyle Minch has skills like Molecular Biology, Research, Systems Biology, Cell Culture, Biochemistry, Cell Biology, Pcr, Life Sciences, Science, Western Blotting.
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1cmich.edu
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Kyle Minch
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Kyle Minch
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