Laura Maiorino Email & Phone Number

Cambridge, Ma, Us

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Cambridge, Massachusetts, United States

Research Experience •Led vaccine translational studies in non-human primates - designing experiments, coordinating plans with vet staff, and data analysis. •Leveraged research expertise in several collaborative projects, resulting in publications in Science, Science Translational Medicine, Nature BME, PNAS. •Designed mRNA and self-replicating RNA vaccines for cancer and infectious diseases.Biotech• Attended Venture Capital University (by Venture Forward and NVCA) • Worked on pre-IND and IND package preparation for an HIV vaccine clinical trial; • Worked closely with CRO for GMP manufacturing of lab-developed adjuvant technology; • Managed collaborations with companies and academic labs leveraging lab developed technology and contributed technical expertise towards translation for Ebola, Malaria and HIV vaccines. Leadership Experience • Headed lab operations, supporting a group of 30+ people. • Managed 6 lab technicians, including schedules, assignments and conflict management. • Responsible for hiring new personnel, performance reviews and development plans. • Developed lab SOPs and assisted lab members with experimental planning • Wrote and reviewed animal use (IACUC) and biological safety protocols, assuring compliance.

Cambridge, Massachusetts, United States

Research Experience• Developed a mouse model for local treatment of lung cancer with intratumoral immunotherapies in Darrell Irvine's lab at the Koch Institute For Integrative Cancer Research at MIT • Granted a JSMF Postdoctoral Fellowship Award in Understanding Dynamic and Multi-scale SystemsLeadership Experience • MIT Postdoctoral Association Vice-President, co-led advocacy efforts with the administration • Managed and hosted a departmental seminar series on Immunology

Cold Spring Harbor, Ny, Usa

Research experience: • Discovered a mechanism of immune-mediated protection from pancreatic cancer metastasis in Dr Mikala Egeblad's lab at the CSHL Cancer Center • Contributed to the discovery of how Neutrophil Extracellular Traps (NETs) promote breast cancer metastasis • Collaborated on projects in immuno-oncology and inflammation, cancer biology, drug delivery • Developed longitudinal imaging technique • Employed intravital imaging, mouse models of cancer, CRISPR/Cas9 genome editing, histology, bioluminescence imaging, 3D cell culture, flow cytometry and other techniques • Won outstanding graduate student research talk and poster prizes • Awarded Boehringer Ingelheim Fonds Ph.D Fellowship (2015-2017)Writing/editing experience: • Provided critical feedback on research manuscripts and grants prior to submission • Wrote a News&Views article for Nature Cell Biology Leadership/organization experience: • Held five workshops on Basic and Advanced use of Adobe Illustrator for scientific communication

Milano, Italia

Research experience: • Contributed to the discovery of a function of the COP9 Signalosome, a regulator of E3 ubiquitin ligases, during the oncogene-induced response in controlling oncogene levels and proteins involved in DNA replication origin. • Studied the consequences of genetic and pharmacological dysregulation of Cullin-RING E3 ligase complexes in cancer through the study of multiple myeloma and hepatocellular carcinoma.

Milano, Italia

Research experience: • Studied the role of the COP9 Signalosome, a regulator of E3 ubiquitin ligases, as a gate keeper during the initiation of liver cancer in a mouse model

Doctor Of Philosophy - Phd, Oncology And Cancer Biology

Thesis project: Identification of cancer-cell intrinsic and host-mediated cellular mechanisms of metastasis through intravital imaging

Master’S Degree In Medical, Molecular And Cellular Biotechnology, 110 /110 Cum Laude And Honorable Mention

Thesis project: Study of ubiquitin ligases in organ homeostasis and cancer initiation using genetically engineered mice and in vitro models.

Bachelor’S Degree In Medical And Pharmaceutical Biotechnology, 110 /110 Cum Laude And Honorable Mention