Larissa Benjamin Email & Phone Number

Leiden, Zh, Nl

Leiden, Holanda Do Sul, Países Baixos

Technology transfer for CAR-T cell therapy in Europe.

Embu Das Artes

Isolation and purification of fermentation based APIs.Technology transfer. Mass and energy balances, evaluation of production capacity/bottlenecks. Coordination of lab and CP tests to assess quality, yield, productivity and operational parameters. Definition of process simulation flowsheets, IPC, SFDs, SOPs, BPRs, time schedule, risk analysis. Documentation for licenses, registration, quality deviation, change control and URS. Great interface with areas of engineering, automation… Show more Isolation and purification of fermentation based APIs.Technology transfer. Mass and energy balances, evaluation of production capacity/bottlenecks. Coordination of lab and CP tests to assess quality, yield, productivity and operational parameters. Definition of process simulation flowsheets, IPC, SFDs, SOPs, BPRs, time schedule, risk analysis. Documentation for licenses, registration, quality deviation, change control and URS. Great interface with areas of engineering, automation, maintenance, supply, PPC, quality, environment and research.Implementation of improvement projects for increasing productivity, yield, diversification and reduction of raw material. CAPEX, FTE and production scenarios evaluation. Technical-economic feasibility studies, planning, testing, implementation, validation, monitoring and documentation.Coordination of the operational team (8P in 2nd shift) during tests, pilot, engineering (pre validation lots). As senior leader and along with two other leaders, responsible for guaranteeing process control and operational performance by coordination of the operational team in 3 shifts (8P/shift), performing activities such as training, planning, supervision, technical data gathering, judgment, implementation and control. CP Scale: liquid-liquid extraction, decantation (SDC, gravity), distillation, adsorption (AC), vacuum filtration, HPLC (Sartorius), crystallization (antisolvent), drying (oven) and packing (ISO 8 class). Technically responsible for downstream process in the tacrolimus API project for plant renovation, to attain process validation and commercial scale production. Business trip to Biocon facilities in Bangalore, India (J-M 22), for technical immersion and training in isolation, purification, solvent recovery and waste treatment plants. Coordination of technical discussion in a business trip from Biocon staff to Brazil (S 22). Coordination of technical establishments for executive project along with third party company. Show less

São Paulo E Região, Brasil

Physical technologies (magnetic field and ultrasound) for prevention of calcium carbonate scaling in pipelines from oil extraction wells.Technical review. Planning, coordination and evaluation of bench tests. Specification of equipment for bench tests. Technology parameters definition. Preparation of technical reports, attending technical events and presenting papers (f.i. VIII ENAHPE 2019).Project management support regarding resources, schedule and technical team (hiring… Show more Physical technologies (magnetic field and ultrasound) for prevention of calcium carbonate scaling in pipelines from oil extraction wells.Technical review. Planning, coordination and evaluation of bench tests. Specification of equipment for bench tests. Technology parameters definition. Preparation of technical reports, attending technical events and presenting papers (f.i. VIII ENAHPE 2019).Project management support regarding resources, schedule and technical team (hiring, training and activities coordination). Show less

Limeira, São Paulo

Isolation and purification of fermentation based amino acids.Technology transfer. Development of production routes. Mass and energy balances, evaluation of production capacity and bottlenecks. Coordination of lab, pilot and commercial tests to assess quality, yield, productivity and definition of operational parameters. Scale up. Definition of process simulation flowsheets (product, co-pro and effluents), IPC, SFDs, SOPs, BPRs, risk analysis and documentation for licenses and… Show more Isolation and purification of fermentation based amino acids.Technology transfer. Development of production routes. Mass and energy balances, evaluation of production capacity and bottlenecks. Coordination of lab, pilot and commercial tests to assess quality, yield, productivity and definition of operational parameters. Scale up. Definition of process simulation flowsheets (product, co-pro and effluents), IPC, SFDs, SOPs, BPRs, risk analysis and documentation for licenses and registrations. Great interface with the areas of production, engineering, automation, maintenance, supply, PPC, quality, environment and research.Implementation of improvement projects for increasing productivity, yield, quality (new grades/markets), diversification and reduction of raw material consumption. Technical-economic feasibility studies, planning, testing, implementation support, validation, monitoring and documentation.Support and troubleshooting for process control and operational performance (quality, productivity, yield, environment and safety). Planning, testing, physical-chemical analysis judgment, implementation support, validation and control.Coordination of the purification support team of technicians and engineers in tests, start ups and production campaigns through training, supervision, technical data gathering, judgment and action in order to guarantee production within operational performance targets.CP scale: bacterial inactivation in broth (acidification/continuos sterillization), flocculation, MF, UF, ionic exchange (CER, AER, D-Resin, ISEP), affinity chromatography (CSEP), adsorption (GAC, AC), concentration (FFE), crystallization (cooling, FCE, pH change), separation (SSC, Syphon Peeler), decantation (SDC), drying (fluidized bed, paddle) and packing. Business trip to Ajinomoto in Saga, Japan (Nov 2016), as a part of Histidine process technical transfer to Brazil. Lab and pilot plant tests. Technical visit and immersion to commercial plant. Show less

Limeira Area, Brazil

Campinas Area, Brazil

Active and reactive prospection of business opportunities, through marketing campaigns, onlinetechnical seminars, website, fairs and events.Organization of events to customers. Organization and work at company’s stand at Brasilplast Fair in2011.Attending visits and technical meetings at costumers along with sales team.

Pós-Graduação Lato Sensu - Especialização, Administração Industrial

Mestrado Profissional, Processos Industriais

Disciplinas: Desenvolvimento de Processos, Engenharia Econômica, Otimização de Processos, Energia em Processos, Biotecnologia, Tecnologia.

Bacharelado, Engenharia Química

Activities and Societies: Empresa júnior (2006 a 2009), sendo Diretora de Projetos Sociais em 2008, com prêmios de projeto social e.

English As A Second Language, English