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Highly motivated bilingual science professional with extensive research and translational background in the biotechnology industry, passionate about helping bring drugs to patients. Extensive practical experience in all areas of the drug discovery process from concept to clinic. Supported regulatory submissions of several oncology and infectious diseases drug candidates for first-in-human studies as well as a biologics license application. Seasoned line manager with long-term direct responsibility for a large multi-disciplinary department. Committed to promoting a vibrant and positive working culture through the pro-active sharing of ideas and by fostering the growth and development of others. Substantial experience in leading and contributing to matrix teams. Broad knowledge of cellular biology and immunology.
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Vp - Nonclinical DevelopmentEnara BioOxford, Gb -
Head Of Research And Preclinical DevelopmentSynaptixbio Ltd.Oxford, Gb -
Consultant - Research And Preclinical DevelopmentSelf-Employed Nov 2022 - Present• Offers advice in Preclinical Development from early research to regulatory submissions, including molecule screening and lead candidate selection.• Contributed to successful IND.• Member of Scientific Advisory Board• Capacity to advise on small company operations and expansion, as well as people and programme management.
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Head Of Research And Preclinical DevelopmentSynaptixbio Ltd. Jul 2022 - PresentOxford , Oxfordshire, Gb -
Director/Head Of Pipeline BiologyImmunocore Apr 2020 - Jun 2022Abingdon, England, Gb• Lead the functional area responsible for TCR Discovery and Preclinical/non-clinical activities, with 3 direct reports and ~25 indirect reports.• Oversee all non-clinical cell biology research activities related to i) identification of T cell receptors as bases for ImmTAX molecules across a variety of disease areas for both wholly-owned and partner programmes, ii) identification of lead drug candidates, and iii) all non-clinical regulatory activities in collaboration with Clinical and Regulatory teams, including delivery of non-clinical documents for submission to health authorities (including two successful IND submissions or equivalent, one ongoing BLA).• Provide regular updates of regulatory and clinical documents following the initiation of first-in-human studies. Involved in clinical development portfolio governance meetings.• Oversee all cell biology process enhancement activities aiming to improve or accelerate the development of drug candidates (e.g. high throughput screening of molecules using automation).• Lead a franchise of several interconnected programmes for efficient and coordinated strategic delivery.• Core member of the Research Portfolio Committee, which governs and prioritises Research portfolio projects across all disease areas.• Core member of the Research Leadership Team, which ensures the effective functioning of Research at the scientific, personnel, and operational perspectives, and defines Research strategy.• Contribute to personal development of associate directors and scientists, through training, mentoring, and coaching. -
Head Of Preclinical BiologyImmunocore Aug 2019 - Apr 2020Abingdon, England, Gb• Led the functional area related to Preclinical activities/non-clinical activities mentioned above. -
Group Leader - Preclinical BiologyImmunocore Jan 2018 - Aug 2019Abingdon, England, Gb• Led a group of six scientists with responsibility for (i) screening bispecific molecules in several oncology programmes, (ii) generating preclinical data for regulatory submissions, (iii) developing new cellular models including 3D models, and (iv) in collaboration with other departments optimizing high throughput screening techniques. • Co-lead for the clinical development of a drug candidate, including the coordination of a matrix team of functional experts, definition of the clinical strategy for the first-in-human and subsequent studies, reporting to senior executive management. • Preclinical functional lead for the clinical development of a drug candidate overseeing data generation and completion of clinical documents for regulatory authorities.• Contributed to the implementation of programme leadership and matrix teams in different parts of the company.• Contributed to company-wide efforts to implement informatics tools for optimal management of the pipeline.• Selected for and participated in Leadership and Management training, and part of a team aiming to develop leadership and self-development workshops for company staff.• Contributed to personal development of scientists, through training, mentoring, and coaching. -
Senior Scientist - Manager - Preclinical BiologyImmunocore Jan 2017 - Dec 2017Abingdon, England, Gb• Led a group of six scientists with responsibility for (i) screening bispecific molecules in several oncology programmes, (ii) generating preclinical data for regulatory submissions, (iii) developing new cellular models including 3D models, and (iv) in collaboration with other departments optimizing high throughput screening techniques.• Contributed to the initiation of programme leadership and matrix teams, and acted as a programme leader and preclinical functional lead. -
Senior Scientist I - Preclinical BiologyImmunocore Jan 2016 - Dec 2016Abingdon, England, Gb• Led a group of two scientists with responsibility for (i) screening bispecific molecules in several oncology programmes, and (ii) developing new cellular models including 3D models.• Contributed to preclinical data generation for regulatory submission of a drug candidate, contributed to the writing of study reports. -
Senior Scientist Ii - Preclinical BiologyImmunocore Jul 2014 - Dec 2015Abingdon, England, Gb• Contributed and led screening of molecules in collaboration with an industrial partner.• Initiated the development of 3D cellular models. -
Translation ServicesSelf-Employed Feb 2014 - Jun 2014• Translation (English to French) of technical documentation for scientific companies (e.g. request for information documents).
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Phd - Experimental MedicineMcgill University 2007 - 2013Montreal, Qc, Ca• Initiated or developed research projects investigating the molecular processes of cancer progression and search for markers of progression or predictive/prognostic markers, including the role of TGFbeta on tumour initiation and progression, cancer signalling, and regulation of cytoskeleton.• Collaborated with physicists and chemists in Polytechnique Montreal within a multidisciplinary team for a new laser-based therapeutic strategy for skin cancer treatment.• Collaborated with another cancer research laboratory for the development of buffers for fast semi-dry transfer of proteins for Western blot.• Wrote one grant application for the Canadian Institutes of Health Research and one grant application for L’Oréal, ten studentships applications, two peer-reviewed first-author research articles, two peer-reviewed first-author review articles, one web review, and one book chapter, participated in the writing of two second-author collaborative research articles.• Managed laboratory administration and budget for 3 years, acted as an onsite representative for Bio-Rad supply centre and managed purchasing for onsite customers for 3 years.• Trained and coached seven undergraduate students. -
Research ScientistCea Mar 2006 - Aug 2006Paris, France, Fr• Developed a project on the immunogenic properties of the HIV Tat protein, using cell-based assays, biochemistry, and in vivo studies. -
Research ScientistAston University Jun 2005 - Jul 2005Birmingham City Centre, West Midlands, Gb• Developed a project on the effects of lovastatin on breast cancer cells, using cell-based assays and biochemistry.• Acted as teaching assistant. -
Research ScientistÉcole Normale Supérieure De Cachan Feb 2005 - Mar 2005Gif-Sur-Yvette, Île-De-France, Fr• Developed a project about the effects of retinoic acids in Ewing Sarcoma, including on cytoskeleton and cell migration. -
Research ScientistUniversité Henri Poincaré, Nancy 1 Jul 2004 - Jul 2004Nancy, France, Fr• Contributed to an ongoing project about the regulation of an integrative and conjugative element ICESt1 in Streptococcus thermophiles, developed molecular biology techniques. -
Research ScientistUniversité Henri Poincaré, Nancy 1 Sep 2002 - Jun 2003Nancy, France, Fr• Contributed to an ongoing project about the effects on ozone on poplar growth and metabolism,developed biochemistry techniques (part time).
Laure Humbert Skills
Laure Humbert Education Details
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Mcgill UniversityExperimental Medicine -
Institut National Agronomique Paris-GrignonSciences For Biological And Food Industries -
Lycée Henri PoincaréBiology Chemistry Physics Geology
Frequently Asked Questions about Laure Humbert
What company does Laure Humbert work for?
Laure Humbert works for Enara Bio
What is Laure Humbert's role at the current company?
Laure Humbert's current role is VP - Nonclinical Development.
What is Laure Humbert's email address?
Laure Humbert's email address is la****@****ore.com
What schools did Laure Humbert attend?
Laure Humbert attended Mcgill University, Institut National Agronomique Paris-Grignon, Lycée Henri Poincaré.
What are some of Laure Humbert's interests?
Laure Humbert has interest in Cooking, Traveling, Various Sports, Education, Reading, Drawing And Painting, Ping Pong, Bike, Squash, Tennis.
What skills is Laure Humbert known for?
Laure Humbert has skills like Cell Biology, Cancer Research, Western Blotting, Cell Culture, Molecular Biology, Laboratory, Fluorescence Microscopy, Cell, Microscopy, Immunohistochemistry, Transfection, Cell Viability Assays.
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