L.-C. Campeau Email and Phone Number
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L.-C. Campeau obtained his Ph. D. degree in 2007 with the late Professor Keith Fagnou at the University of Ottawa in Canada as an NSERC Doctoral Fellow, after completing his B.Sc. in Biopharmaceutical Sciences. He was the recipient of the Pierre Laberge Prize for the best Ph.D. thesis in the Science Faculty. The Faculty of Science awarded him the inaugural Young Alumni Award in 2016 and in 2022 he received the inaugural Department of Chemistry and Biomolecular Sciences Distinguished Alumni Award. L.-C. first joined Merck Research Laboratories at Merck-Frosst in Montreal in 2007 making key contributions to the discovery of Doravirine (MK-1439) for which he received a Merck Special Achievement Award. In 2010, he moved from Quebec to New Jersey, where he has served in roles of increasing responsibility Head of Catalysis & Automation, Head of Discovery Process Chemistry and Head of Process Chemistry. L.-C. is currently Associate Vice President and the Head of Small Molecule Process Research and Development, leading a team of smart creative scientists and engineers developing innovative solutions in support of all discovery, pre-clinical and clinical active pharmaceutical ingredient deliveries for the entire Merck portfolio for small-molecule therapeutics. Over his tenure at Merck, L.-C. and his team have made important contributions to >40 clinical candidates and 7 commercial products to date. Under his leadership, his organization has received the EPA’s Green Chemistry Challenge Award four consecutive years and received the Heroes of Chemistry Award for their work on Molnupiravir in 2022. His passion for scientific excellence is exemplified by >80 publications and patents, several successful collaborations with key academics, and >85 invited lectures worldwide. As a proud Canadian, L.-C. continues his engagement in the Canadian chemistry community, serving 4 years on the NSERC Discovery Grants committee (2019-2022) and currently sits on the NSERC National Awards Selection Committee. L.-C. was elected Fellow of the Royal Society of Canada in 2022.
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Associate Vice President, Head Of Small Molecule Process R And DMerckRahway, Nj, Us
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Associate Vice President, Head Of Small Molecule Process R&DMerck Jan 2022 - PresentRahway, New Jersey, UsThe Small Molecule Process R&D organization has a strong presence at the CMC hub in NJ as well as teams across Merck sites in CA, PA and MA as well as MSD sites in UK and Switzerland.- Accountable for all API supply for pre-clinical and clinical development.- Responsible for defining the commercial manufacturing process for Merck’s small molecule APIs and bioconjugate products.- Member of Merck Global Leadership Team- Member of the Merck Process R&D Leadership Team
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Executive Director, Head Of Process Chemistry And Discovery Process Chemistry,Merck Aug 2016 - Jan 2022Rahway, New Jersey, UsExecutive leader of Process Chemistry teams at MRL discovery sites and CMC hub in NJ.- Responsible for eliminating synthetic bottlenecks in discovery and early development efforts to accelerate the discovery of novel therapeutics.- Led the Discovery Process Chemistry organization which transitioned >30 pre-clinical candidates and >20 successful first-in-humans- Leveraged experience and diligent prioritization to solve some of the most difficult problems for clinical and commercial process development leading to filing and approvals for Bridion™ (MK-8616), Welireg™ (MK-6482), and molnupiravir (MK-4482).- Co-lead of Early Development Team for MK-0616, Merck oral PCSK9 inhibitor.- Member of Merck’s Discovery and Translational Research Committee responsible for oversight of the entire pre-PhII portfolio.
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Director, Process ChemistryMerck Mar 2015 - Aug 2016Rahway, New Jersey, Us- Lead a team of 17 scientist responsible for defining the final manufacturing route for Merck small molecule APIs, including MK-8931, MK-3682, ZerbaxaTM (MK-7625A) and gefapixant (MK-7264)- Lead the department Capacity Planning Team charged with assigning contacts & resources for projects in support of upcoming API campaigns in the Merck pipeline. - Co-lead of the API Oversight Committee responsible for setting strategy for drug substance manufacturing development from FIH to Filing and providing oversight to API development teams.- Led teams that received 3 EPA Green Chemistry Awards (MK-3682, MK-7264, MK-7625A)
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Director, Head Of The Catalysis & Automation LaboratoryMerck Oct 2013 - Mar 2015Rahway, New Jersey, UsHead of the Catalysis and Automation Laboratory- Catalysis and high-throughput experimentation specialty group focused on the discovery, optimization and development of new catalytic reactions and capabilities, as well as ensure its successful application across the global chemistry network with impact on Merck products like ZepatierTM and important clinical candidates like uprifosbuvir, ruzasvir.- Oversaw the development and delivery of important new technologies, methods and capabilities to Merck’s PR&D group including 1) Photocatalysis capabilities, including photoflow reactors; 2) New methods for reaction benchmarking and miniaturization of high-throughput experimentation. 3) Impactful novel catalytic methodologies in support of Merck’s portfolio.
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Associate Principal Scientist, Discovery Process ChemsitryMerck Nov 2010 - Oct 2013Rahway, New Jersey, UsGroup leader in New Jersey Discovery Process Chemistry Group- Leverage process research expertise and technology for support of medicinal chemistry programs enabling the discovery and development of multiple pre-clinical candidates for cardiovascular diseases (MK-8626 and MK-8892).- Pioneered the idea of building a computational model for molecular complexity based on chemist’s intuition, recruiting collaborators across Merck to help develop a crowdsourced approach. This model is the foundation behind Merck’s ability to set PMI targets for our commercial processes with a 2-D chemical structure alone.- Discovery Process Chemistry Lead on six different Drug Discovery Core Teams.- Designed and implemented IT workflow management (submission/tracking) tool for management of outsourced activities.- Developed novel innovative synthetic methods with impact on drug discovery. - Supervised 5 Ph.D. and 3 M.Sc. scientific staff.
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Senior Research Chemist, Process ResearchMerck Aug 2007 - Oct 2010Rahway, New Jersey, UsDevelopment, Scale-up and Application of Chemical Processes for the Synthesis of Active Pharmaceutical Ingredient (API).- Made critical scientific contributions to several kilo-scale deliveries under Good Manufacturing Practice (GMP) with innovative, scalable and efficient processes including MK-6096 and MK-5632.Discovery Process Chemistry Lead on Drug Discovery Core Teams- Leverage process research expertise and technology for support of medicinal chemistry programs enabling the discovery and development of Doravirine (MK-1439), an HIV NNRTI approved for treatment of HIV as PifeltroTM and DelstrigoTM.
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Co-Host Of The Pharm To Table PodcastPharm To Table Podcast Jul 2020 - PresentA podcast hosted by L.-C. Campeau and Dani Schultz that dives into the stories about the people behind the chemistry and science that happens at #MerckChemistry.Follow us on Twitter at @PharmToTablePod
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Teaching AssistantUniversity Of Ottawa 2003 - 2007Ottawa, On, CaGeneral Chemstry, Organic Chemistry I and II (1st and 2nd year level, French and English Sections)- Presented problem sets and supervised laboratory exercise.Advanced Organic Synthesis & Reaction Mechanisms (4th year level)- Prepared and presented lectures and problem sets. -
Research AssistantNational Research Council Canada Sep 2002 - Apr 2003Ottawa, Ontario, Ca- Conducted research in the field of diversity oriented synthesis and organic synthetic methodologies.- Developped novel cores for DOS.
L.-C. Campeau Skills
L.-C. Campeau Education Details
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University Of OttawaChemistry -
University Of OttawaBiopharmaceutical Sciences
Frequently Asked Questions about L.-C. Campeau
What company does L.-C. Campeau work for?
L.-C. Campeau works for Merck
What is L.-C. Campeau's role at the current company?
L.-C. Campeau's current role is Associate Vice President, Head of Small Molecule Process R and D.
What is L.-C. Campeau's email address?
L.-C. Campeau's email address is ca****@****ail.com
What schools did L.-C. Campeau attend?
L.-C. Campeau attended University Of Ottawa, University Of Ottawa.
What skills is L.-C. Campeau known for?
L.-C. Campeau has skills like Organic Synthesis, Organic Chemistry, Medicinal Chemistry, Drug Discovery, Chemistry, Catalysis, Pharmaceutical Industry, Gmp, Drug Development, Drug Design, Team Leadership, Synthetic Organic Chemistry.
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