Leanne Minall Email & Phone Number

- Working with scientists at the Collins lab, MIT to build AI for antibiotic drug discovery - Fundraising and technical lead on grants - Database building of ML training - Overseeing a translational drug pipeline to preclinical studies - TPP and commercial analysis- IP strategy

• Directing R&D programs through a global network of CROs, planning antibiotic drug development for multiple TPPs and RoAs.
• Landscape mapping of current antibiotic unmet needs and strategies for overcoming poor market incentives using a non-profit business model and industry partnerships.
• Liaising with clinicians to define unmet needs and patient population specific TPPs.

Head of Science across two labs directing R&D efforts for the cell-based production of therapeutic mRNA. - Managing > 18 scientists. - IP and preclinical strategy - inventor on 2 patents - Lab building, hiring and budgeting.- Fund raising (private and public)

Consulting on scientific and fund raising strategies for RNA drug delivery

Sevenoaks, GB

Planning IP and R&D strategy for novel nucleic acid delivery technologies

• Directing RNA nasal formulation development, managing the analytical and production strategy to GMP, including RNA drug substance production scale up to GMP.
• Authoring SOPs and interacting with government funding agencies and academic partners.

New York, New York, US

• I joined the Novel Delivery Technologies Group, part of Pharmaceutical Research and Development, Pfizer.
• Lab-lead for projects including: the COVID vaccine, conjugated oligonucleotides and nanoparticle-protein conjugates.
• Chemical expertise with lipids, RNA, nanoparticles, proteins, conjugation methods, multiple analytical techniques and stability strategies.
• Internal due diligence experience
• Pfizer 'Business of Science' certification

Nijmegen, NL

Working on immunogenic hydrogel technologies. Techniques:-The chemical modification of polysaccharides -Biocognation chemistry with antibodies and protein complexes -Confocal microscopy -Human T cell culture -Immunostaining, flow cytometry and ELISA

Auckland, NZ

I worked in collaboration with the Dunbar and Brimble labs on vaccine constructs for human ex-vivo T cell priming.Techniques:-Ex-vivo human DC culture conditions optimisation-DC maturation and co-stimulation -Human naive T cell culturing and priming -Antigen uptake and presentation

Oxford, Oxfordshire, GB

I undertook a one year post-doctoral contract, working in collaboration between the Ben Davis and Quentin Sattentau groups at Oxford University. I worked on the synthesis of protein-reactive carbohydrates and the modification of whole protein vaccine candidates. Techniques:-Organic synthesis-ELISA-Flow cytometry-T cell assays-Luminex assay-Mouse.

Oxford, Oxfordshire, GB

I completed my D.Phil in Chemical Biology under the supervision of Prof. Ben Davis, my thesis focused on chemical modification of adenoviral vectors for DNA vaccination and immune evasion. My paper ‘Synthetic glyco-viruses for targeted DNA therapy and immune evasion’ is currently in submission. Working at the interface of chemistry and immunology has.

Doctor Of Philosophy (Ph.D.), Chemical Biology

Certificate, Fundamentals Of Biomanufacturing

B.Sc. Hons, Chemistry

Certification, Quality Assurance And Control