Alexandre Leduc Email & Phone Number

Village-Neuf, Fr

Village Neuf

I work on host-microbiome interactions. Mainly by performing metagenomic analysis of the microbiome, transcriptomic studies and developing in vitro models for gut health.I am also a member of the animal welfare committee at the ANH R&D center Village-Neuf.

Caen, Normandie, France

Teaching :Bachelor's degree (animal biology and physiology)Master's degree (fields of molecular biology and omics)Supervision of studentsResearch :Nutrition and health links using NGS (RNAseq)HPLC / MS chemical and functional characterization of bio-active peptides in complex protein matrix

Région De Caen, France

Identification of transcriptomic biomarkers related to skin side effects after cancer treatment:* I joined an ongoing project and implemented a RNAseq analysis with time, budget and samples available in collaboration with former partners.* Conduction of NGS Illumina analyses (lncRNA, mRNA and microRNA differential expression).* Presentation of results during meeting and congress poster session.* Writing a publication as author.

University Of Caen

PhD at the University of Caen (Lower-Normandy):Development of hydrolysates for aquafeed formulation: structural standardization and functional optimization. (CIFRE grant)* Interdisciplinary teamworking and network.* Animation of professional meetings.* Development of innovative tools (Software, method, cell-based).* Supervision of staff and students.* Report writing* Identification of bioactive peptides: functional assays, HPLC, ESI, MALDI-TOF-TOF.* Transcriptomic analysis: RNAseq, data manipulation, differential expression, metabolic pathways.* In vitro assay: antioxidant, antibacterial.* Patent : EP3590355 MYOTROPIC PEPTIDES AND USES THEREOF

Study of an anti-bacterial peptide (K4) intended for aquaculture:* Anti-bacterial study of K4 on aquatic bacterial pathogens (MIC, MBC)* Degradation kinetic of K4 by HPLC and MALDI-TOF-TOF* Activity report.

Umr Borea

Identification of anti-cancerous and anti-diabetic peptides in shark:* Peptide extraction and concentration* Purification of active fractions by HPLC* Identification of the candidate peptides by MALDI-TOF-TOF / Transcriptomic database* Analysis of the candidate peptides (precursors, 3D conformation, signal peptide, electric charge)* Conduct of meetings* Activity report

Cclc François Baclesse Caen

Effects of irradiation with carbon ions on human skin.* Irradiation at the GANIL facility (Carbon ion) and at the Francois Baclesse Cancer Control Center (X-Rays).* Experiments (cell culture, qPCR)* Activity report

Ganil - Caen

Effects of irradiation with carbon ions on human skin* Coordination of teams (Administrative workout, team planning and output of irradiated samples)* Irradiation of carbon ion samples (GANIL) and X-Rays (Francois Baclesse Cancer Control Center)* Experiments (cell culture, PCR, antioxidant assay, comet assay).

Guyane Française

Doctor Of Philosophy - Phd, Cell/Cellular And Molecular Biology

Diplôme D'Ingénieur, Génie Biologique

Bts Biotechnologie, Biotechnologie

Expérimentation Animale - Conception Et Réalisation De Procédures Expérimentales. Espèces Aquacoles, Expérimentation Animale