Senior medicinal chemistry team leader with experience of both small and large molecule medicinal chemistry design and synthesis.Currently leading a cross-disciplinary group of Medicinal Chemists, Chemical Biologists, Structural Biologists and Computational Chemists towards the discovery of small molecules modulators of RNA at Arrakis.Worked on a number of therapeutic areas including cardiovascular, genitourinary, sexual health, pain, rare diseases and anti-virals across a diverse classes of targets such as GPCR's, enzymes, nuclear hormone receptors, ion channels and protein-protein interactions.Experience of structure and ligand-based medicinal chemistry design on a range of modalities including small molecules, peptides, peptidomimetics, protein epitope mimetics, microproteins, bioconjugates and antigens for therapeutic vaccines and monoclonal antibodies, antibody drug conjugates, nanoparticles and DNA encoded libraries.An author on over 60 publications or patents and made contributions to compounds that have been in the clinic.Specialties: Medicinal Chemistry, Drug Design, Chemical Biology, Bioconjugation, Peptidomimetics, HTS triage, Hit to Lead, Lead Optimization, pre-clinical Candidate Nomination, Synthetic Organic Chemistry, Target Selection, DNA encoded libraries, ADC's, RNA