My career in biotechnology started many years ago when I began to brew beer and make wine in the kitchen of the apartment that I shared with my wife. During my career with The Clorox Company I was offered the opportunity to turn my hobby into a profession by growing a recombinant bacterium that produced a protease that was engineered to be used in laundry product applications. The rest, as they say, is history and after 27 years in the biotech industry I find myself with a skill set that encompasses producing pharmaceutical proteins using E. coli, Saccharomyces, Pichia pastoris, mouse myeloma and CHO host cell lines.My most recent experience in upstream process development is the design of commercial processes for the production of biosimilar molecules. The production of biosimilars presents unique opportunities for development due to their clear product quality goals combined with unknown manufacturing protocols. I have also had the chance to work on many early stage molecules, developing processes to make GMP material for use in phase I clinical trials.Each stage in the lifecycle of a biological product has its challenges. Early stage processes are often put together with very short timelines, while commercial processes require more meticulous experimentation. Both take a high attention to detail and the ability to work effectively in multidisciplinary environments. I have led teams in the development of upstream processes for both stages and have a track record of successfully working with challenging molecules.Skills: Bioreactor process development, DOE, data analysis and interpretation, upstream process team leadership, CHO cell culture, GMP process transfer, technical writing.
Listed skills include Cell Culture, Biotechnology, Biopharmaceuticals, Process Simulation, and 10 others.
