• Innovative, dedicated and experienced problem-solver with strong interpersonal and communication skill• 6 year experience in cancer/immuology research and 6 year experience on nano-formulation, gene delivery, bio-active materials research• Experience in functional polymers, nanoparticles, and lipid nanoparticles (LNPs) including design, synthesis, characterization, formulation and testing of the materials in vitro and in vivo• First demonstration of carbon nanotubes for topical siRNA delivery which resulted in 94% inhibition of melanoma progression in a rodent model with a team of biologists• Effective communication skill: 8 publications, 2 first-authored articles, 1 book chapter and 11 scientific conference presentations• Good organizational skills and ability to work in a self-directed manner: designed and carried out research project on PhD research
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ScientistAvro Life Science Apr 2021 - PresentWaterloo, Ontario, Ca• Evaluate the business and therapeutic potential of the in-house marcomolecules delivery method for rare diseases• Carry out research on drug/gene delivery -
Laboratory TechnicianPublic Health Ontario Nov 2020 - Mar 2021Toronto, Ontario, Ca• Trains other lab technicians and technologists on Covid testing including RNA extraction and qRT-PCR experiments on both manual and automation platform• Troubleshoot RNA extraction and qRT-PCR contamination• Carry out high volume Covid samples aliquot, RNA extraction, and qRT-PCR manually and using automation platform• Uses LIMS to record testing, assists in data analysis and reporting -
Postdoctoral ScientistDalriada Therapeutics Sep 2017 - Apr 2020Mississauga, Ontario, Ca•Collaborately established a new laboratory in a start-up environment•Maintained mammalian cell culture and carried out troubleshooting, problem-solving, analysed data, and evaluated results in accordance to the turnaround time and changing priorities for SDS-PAGE/Western blot, flow cytometry and cytotoxicity data•Carried out method transfer, method development, optimization, troubleshooting and writing of SOPs•Prepared weekly report summary -
Team Lead, Gene SynthesisBio Basic Inc. Jan 2015 - Jul 2017Markham, On, Ca• Successfully established gene synthesis department• Carried out troubleshooting, problem solving, analysed data, and evaluated results in accordance to the turnaround time for DNA sequencing experiments (annual revenue $200k)• Maintained inventory, DNA sequencing machine and other equipment• Carried out quality control (QC) experiments and prepare QC reports in a timely manner• Developed, tested, and optimized existing and new in house QC protocol• Provided scientific and technical advice on experiments and production line• Trained 3 other junior lab technicians -
Project AssistantHkust Nov 2005 - Sep 2007Kowloon, Hong Kong, HkDetermined multi-dimensional phrase equilibrium (GC, HPLC, UV-vis, KF titration, DSC) for the design of industrial purification resulted in enhanced collaborations with industrial partnersAnalyzed the components in waste water for waste water purification from the funding of CHTC Fong’s (00641.HK) -
Assistant Chemical EngineerTuv Rheinland Hong Kong Jul 2004 - Jul 2005Advised the legal requirements (EU, LMBG) for consumer products importation to Europe in a professional manner resulting in new and return customersCoordinated the laboratory tests (EN, ISO, ASTM) and generated reports in a timely manner and handled all documents with reference to SOP and in a GDP
Leo Siu Skills
Leo Siu Education Details
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Western UniversityPathology -
The University Of Hong KongChemistry
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The Hong Kong University Of Science And TechnologyChemsitry
Frequently Asked Questions about Leo Siu
What company does Leo Siu work for?
Leo Siu works for Avro Life Science
What is Leo Siu's role at the current company?
Leo Siu's current role is Scientist at Avro Life Science.
What schools did Leo Siu attend?
Leo Siu attended Western University, The University Of Hong Kong, The Hong Kong University Of Science And Technology.
What are some of Leo Siu's interests?
Leo Siu has interest in Cooking, Science, Education, Video Gaming, Science And Technology, Watching Football, Chemistry, Human Rights, Digital Photography, Philosophy.
What skills is Leo Siu known for?
Leo Siu has skills like Chemistry, Science, Hplc, Cell, Western Blotting, Research, Sirna, Laboratory, Characterization, Nanotechnology, Cancer, Analytical Chemistry.
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