Leslie Sharp Email & Phone Number

Providing consulting services for the Life Sciences, Biotechnology, and Pharmaceutical industries serving both small and large sized organizations. Particular expertise in biological therapeutics and cancer immunotherapy agents.Specific deliverables include:- Strategy development and scientific portfolio recommendations- Project plans and leadership - Outreach to KOLs, other scientists, and customers- Competitive analysis and strategic recommendations- Assay development and screening

Phoenix, Az, Us

OncoMyx Therapeutics is developing oncolytic immunotherapies based on the myxoma virus (MYXV) platform to orchestrate an immune response and treat cancer. Our therapeutic platform includes several best-in-class features. Our pipeline includes both monotherapies and therapies to be used in combination with immune checkpoint blockade and other immuno-modulatory approaches, offering significant therapeutic promise to a wide range of cancer targets.

San Diego, California, Us

Vice President, Immuno-Oncology Jan 2017-April 2019Director, Immuno-Oncology June 2015-Jan-2017Responsible for strategy development, portfolio management, and experimental execution to enable therapeutic program progression from target identification through first in human studies for oncology drug discovery including antibody and antibody drug conjugates (ADC), and cancer immunotherapy agentsManage external collaborations with large pharma and international partners as member of joint steering/scientific review committee member. Initiate and manage external collaborations and activities at contract research organizations (CRO) including review of experimental design, experimental execution and data quality, and reported progress

San Diego, Ca, Us

Strategy development, portfolio management, and experimental execution to enable therapeutic program progression from target identification through candidate selection for oncology drug discovery including low molecular weight entities, antibody and antibody drug conjugates (ADC), and cancer immunotherapy agentsInitiate and manage external collaborations with field key opinion leaders Directly supervise six independent research groups composed of Research Investigators and reporting colleagues for a total group size of sixteen colleagues

New York, New York, Us

Strategy development and experimental execution to enable identification and validation of new targets within the breast, ovarian, and prostate cancer disease biology spaceMember of internal governance board responsible for oversight of early research portfolio projectsInitiate and manage external collaborations with field key opinion leaders Directly supervise four independent research groups composed of Senior Principal Scientist and reporting colleagues for a total group size of eleven colleagues

New York, New York, Us

Research Project Leader, responsible for leading multifunctional, cross-site research project team to enable decision making necessary for progression of oncology monoclonal antibody projects through stage gate transitions including IND submissionInitiated and managed external collaborations including review of experimental design and data quality, reported progress at quarterly joint steering committee meetingsTranslational Research representative and Biology Subject Matter Expert, providing preclinical expertise, data, and strategic support to three clinical development teams focused on immunomodulatory monoclonal antibodiesDirectly supervised four Scientist and Senior Scientist level colleagues

New York, New York, Us

Responsible for design and execution of in vitro and in vivo preclinical pharmacology and biomarker experiments for oncology monoclonal antibody programs with antibody dependent cellular cytotoxicity (ADCC) mechanism of action

Developed in vitro assays to evaluate the differentiation potential of stem cellsDesign and oversight of in vivo preclinical safety and efficacy studiesFormulated and implemented plans for process development internally and with a contract manufacturing organization Biological Safety Officer with responsibility for in house training programs and complianceDirectly supervised two Senior Research Associates

Phd, Biology

Bs, Biology