Lisa Lallos Email and Phone Number
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Business focused drug discovery professional with proven expertise in strategic planning and implementing projects in biologics, small molecule therapeutics, vaccines, and cutting edge technologies. Papers and Presentations (of 27):CC Parsy, FR Alexandre, V Bidau, F Bonnaterre, G Brandt, C Caillet, S Cappelle, D Chaves, T Convard, M Derock, D Gloux, Y Griffon, LB Lallos, F Leroy, M Liuzzi, AG Loi, L Moulat, M Chiara, H Rahali, V Roques, E Rosinovsky, S Savin, M Seifer, D Standring, and D Surleraux. 2015. Discovery and Structural Diversity of the Hepatitis C Virus NS3/4A Serine Protease Inhibitor Series Leading to Clinical Candidate IDX320. Bioorg Med Chem Lett. 25(22):5427-36.J.P. Bilello, M. La Colla, C. Chapron, L.B. Lallos, I. Serra, J.M. Gillum, J.F. McCarville, X. Pan-Zhou, M. Seifer, K. Gupta and D.N. Standring. The preclinical profile of the pan-genotypic HCV NS5A inhibitor IDX719 demonstrates its potential for combination therapy. 7th International Workshop on Hepatitis C – Resistance and New Compounds, June 28-29, 2012, Boston, MA.J.F. McCarville, L.B. Lallos, M. Seifer, W. Mazur (Specialist Hospital, Chorzów, Poland), A. Wiercińska-Drapało (Hospital of Infectious Diseases, Warsaw, Poland), K. Pietropaolo, D. Mayers, D.N. Standring. In vivo Resistance Profile of IDX320 after 3 Days of Dosing in Genotype 1 HCV-Infected Patients, 62nd Annual Meeting of the American Association for the Study of Liver Diseases, November 4-8, 2011, San Francisco, CA.L.B. Lallos, B. Li, M.A. Soubasakos, J. Gillum, I. Serra, A. Bonin, J.P. Bilello, M. Seifer, D.N. Standring. In Vitro Resistance and Cross-Resistance Profiles of IDX320, a Potent Macrocyclic HCV Protease Inhibitor, 5th International Workshop on Hepatitis C - Resistance and New Compounds, June 24-25, 2010, Boston, MA.
Pharmadirections, Inc.
View- Website:
- pharmadirections.com
- Employees:
- 28
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Pharmadirections, Inc.Chelmsford, Ma, Us
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Project Manager/Project LeaderPharmadirections, Inc. Jul 2013 - PresentCary, Nc, UsDevelops strategic plans, manages CR/MO-client relationships and their budgets, maintains project timelines and budgets, and writes/submits SBIR/STTR grant applications for biological therapeutics and vaccines, small molecule compounds, and nanoparticle/liposome treatments for oncology, wound treatment, schizophrenia as well as several orphan indications.
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Chapter SecretaryHealthcare Businesswomen’S Association Jan 2014 - Dec 2014Fairfield, New Jersey, Us -
Director, General ProgrammingHealthcare Businesswomen’S Association Jan 2012 - Dec 2013Fairfield, New Jersey, Us• 2012 Chapter Excellence Award• Lead 15 member committee• Establish yearly strategic plan • Propose and coordinate four events per year
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Senior ScientistIdenix Pharmaceuticals Aug 2005 - Sep 2013• Formulated recommendations and represented biology group in a cross-functional, CEO- sponsored corporate strategic planning initiative.• Managed biology group IND submission process for lead protease inhibitor compound. • Created cross-departmental lead compound prioritization process that established a target product profile with go/no go gates.• Increased RT-qPCR assay efficiency and accuracy by 67% and decreased costs by 61% in support of its expanded use in the company’s drug discovery process.• Developed a transient transfection assay for resistance characterization of lead compounds, including generating over 15 mutant HCV replicon constructs.• Created six new reagents in 1.5 months for resistance characterization of lead HCV compounds.• Directed research activities of biology group for generating and characterizing HCV drug resistance to a lead protease inhibitor compound (IDX320) in genotype 1a and 1b replicon models. IDX320-resistant mutations were identified, characterized, and orally presented at an international conference. • Developed and directed innovative studies to support the company’s position on the benefit of combination therapy from different antiviral classes for the treatment of HCV.• Managed career development and achievements of a research associate, resulting in accelerated promotion and special recognition awards.
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Senior ScientistAphios Corporation 2001 - 2005• Author and principal investigator for 2 Small Business Innovation Research (SBIR) grants, totaling $900,000 in new research funds, for the discovery of antiviral compounds to HIV or influenza from marine microorganisms.• Principal investigator for smallpox antiviral discovery SBIR grant.• Designed, executed, and interpreted experiments for antiviral, vaccine, and virus inactivation projects involving HIV, influenza, smallpox, and parvovirus. • Directed cross-functional teams (microbiology, virology, engineering, chemistry) for successful completion of SBIR projects. • Established proof-of-concept for using supercritical fluid technology to physically inactivate HIV.• Developed assays for screening and confirming screening hits from proprietary natural product library.• Led efforts of research associates.
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Postdoctoral FellowHarvard University 1999 - 2000Cambridge, Massachusetts, UsDeveloped and evaluated proprietary methodology designed to target an HIV DNA vaccine to Fc receptor-bearing cells in mice. Developed expertise in:• Cellular immunity techniques including CTL, T helper cell, and tetramer staining assays• Large-scale purification of DNA vaccines
Lisa Lallos Skills
Lisa Lallos Education Details
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New York UniversityImmunology -
New York UniversityImmunology
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Oberlin CollegeBiology
Frequently Asked Questions about Lisa Lallos
What company does Lisa Lallos work for?
Lisa Lallos works for Pharmadirections, Inc.
What is Lisa Lallos's role at the current company?
Lisa Lallos's current role is Project Manager/Project Leader at PharmaDirections.
What is Lisa Lallos's email address?
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What schools did Lisa Lallos attend?
Lisa Lallos attended New York University, New York University, Oberlin College.
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Lisa Lallos has interest in Photograph, Boating, Kids, Cooking, Exercise, Investing, Outdoors, Electronics, Home Improvement, Reading.
What skills is Lisa Lallos known for?
Lisa Lallos has skills like Drug Discovery, Virology, Pharmaceutical Industry, Assay Development, Molecular Biology, Lifesciences, Vaccines, Cross Functional Team Leadership, Project Management, Biotechnology, Ind, Qpcr.
Who are Lisa Lallos's colleagues?
Lisa Lallos's colleagues are Laura Valdes-Mora, Nike Abarret, Cathi Clark, Kathy Mckinley, Tiffany Wang, Christy Damphousse, Tom Richardson.
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