Lauren Toth, Ph.D. Email & Phone Number

Florida, United States

Pelham, New York, United States

Brooklyn, New York, United States

Lead a team of two software development scrum teams within a large federal program that is engineering mission critical biometric capability for federal stakeholders. Apply Scaled Agile Framework (SAFe) and Earned Value Management practices to ensure delivery of high quality software on time and within budget.

Brooklyn, New York

I am the lead on several federal civil opportunity captures, and I apply systems engineering principles to architect public safety solutions for our customers.

Brooklyn, New York

For my third rotation, I continued to manage the Technology Sector’s innovation program while taking on the new role of business development and capture for the New York City Wireless Network (NYCWiN) program. Responsibilities included competitor analysis, opportunity assessment, gate reviews, and proposal development.

Brooklyn, Ny

In my second of three one-year rotations within the FTL program, I had three major responsibilities. First, I managed an internal research and development project to develop a secure mobile data solution for SECRET and TOPSECRET applications across multiple government agencies. Second, I managed the Technology Services Sector Innovation program, which provides resources for employees to explore innovative ideas that align with company goals. Both of these responsibilities required program management skills, such as staffing, budgeting, and project planning. My third responsibility was to support business capture efforts for the NYC Wireless Network (NYCWiN) program, which provides a secure private network across New York City for NYPD, FDNY, ambulances, and other city functions.

Mclean, Va

In my first of three one-year rotations within the FTL program, I served as the genomics and molecular/synthetic biology expert within the Personalized Healthcare (PHC) group of the Health Solutions Business Unit. Through systems integration and predictive analytics, we leveraged genomic and clinical data to improve healthcare and health policy on individual and population levels. The PHC group is leading the transition of healthcare from one that is generalized and reactive to one that is patient-specific and preventative.I wore many hats within the Personalized Healthcare group. In addition to developing machine learning models to predict disease and patient outcomes, I also performed business development and capture tasks, such as customer and partner engagement and proposal development. I also worked closely with Northrop Grumman's Chief Medical Officer on medical initiatives, internal company reviews, and university outreach. As leadership and team building roles, I organized the Health Business Unit's attendance and technical demos at the 2016 HIMSS conference in Las Vegas, NV. Lastly, I collaborated closely with the manager of technology and chief solutions architect to design technical solutions for personalized healthcare.

Durham, Nc

As a Biomedical Engineering PhD student in the Gersbach Lab, I engineered light-inducible systems that can regulate genes in both space and time in living cells for applications in tissue engineering, gene-based therapies, synthetic biology, and basic scientific research. Using custom-designed light-inducible zinc finger proteins and CRISPR/dCas9 effectors, I patterned the differentiation of cells into muscle in vitro and vascular tissue in vivo using a mouse dorsal window chamber model. Furthermore, I led a collaborative project and publication that compared the specificity of TALE- and CRISPR/dCas9 transcription factors using DNA-seq, RNA-seq, and ChIP-seq.Cell and molecular research skills/experience:OptogeneticsSynthetic transcription factor design/targeting (TALE & dCas9 transcription factors)Recombinant protein designMolecular subcloning (DNA purification, digestion/ligation, Gibson assembly, Gateway cloning, competent E. coli preparation/transformation)Quantitative real-time PCR - primer design & optimization, mRNA detection/quantificationGel electrophoresis - DNA, protein/Western blotMicroscopy - Immunofluorescence, confocal, live cell imagingCell culture - mammalian culture, transfection, lentiviral & retroviral production & transductionIn vivo - mouse window chamber model, live imaging

Massachusetts Institute Of Technology

• Optimized conditions for Tetrahymena rostrata growth and antibody production using a new online-sampling/feeding bioreactor system.• Consulted company on how to improve bioreactor system performance; identified key flaws with the oxygen and CO2 sensors that caused automation to fail and decreased culture performance and health

• Designed and performed scale-down shake flask Design of Experiment (DOE) studies to asses raw• material variability in cell line performance and product quality for IXEMPRA (Ipilimumab)• Optimized flow cytometry for Ipilimumab-expressing cells to detect apoptotic populations; I used this method to analyze effects of different media filters on media composition and cellular death• Analyzed data using StatEase DesignExpert and ANOVA statistical analysis

Performed Phase I research for oxidative chemical vapor deposition (oCVD) of conducting polymers.

Langer Lab, Mit

· Created a Heparin/polymeric nanoparticle complex to serve as an electrically-stimulated drug-release and delivery system

Designed a softball bat that has been sold to over 10,000 customers since its release. Optimized shipping, reducing errors and shipping costs. Contacted stores and archived feedback about the company's products.

Bs Chemical Engineering, Double Major In Biology

Doctor Of Philosophy (Phd), Biomedical Engineering

High School

Activities and Societies: Softball, volleyball, basketball, ceramics