Internship
Région De Lyon, France
Development of an ultrasound-guided HIFU Endoscopic Probe for Thermal Ablation of Pancreatic CancersTutor: Cyril LAFON, Director LabTAU - U1032 Research UnitPancreatic tumors currently have an only curative treatment, a heavy surgery, burdened with a mortality of about 5%, which can not be proposed to all patients, especially the most fragile ones. High Intensity Focused Ultrasound (HIFU) provides precise tissue necrosis without damaging the tissue which the ultrasonic beam… Show more Development of an ultrasound-guided HIFU Endoscopic Probe for Thermal Ablation of Pancreatic CancersTutor: Cyril LAFON, Director LabTAU - U1032 Research UnitPancreatic tumors currently have an only curative treatment, a heavy surgery, burdened with a mortality of about 5%, which can not be proposed to all patients, especially the most fragile ones. High Intensity Focused Ultrasound (HIFU) provides precise tissue necrosis without damaging the tissue which the ultrasonic beam passes through. A probe has been made, but an acoustic characterization work is needed to use them soon to destroy areas of the pancreas in pigs and prove the feasibility of the technique.Acoustic characterization of the endoscopic probe•Characteristic impedance measurements for each probe's channel.• Performing pressure measurements in the water with a hydrophone. Measurements of the focal spot size, evaluation of the capacity of the probe and its associated electronics to deflect the beam.• Realization of ultrasonic power measurements by the acoustic balance technique.• Keep a laboratory notebook according to GLP standards (ISO9001 certified laboratory)• Provide a measurement report.• Operating room tests at the Institute of Experimental SurgerySkills and qualities• Competence in metrology• Rigor• Editorial capacity Show less