He received both his BA in Biophysics and PhD in Applied Physics and Bioengineering from UC Berkeley. He joined the faculty at the UC Berkeley in 1999 after more than a decade of industry experience. He became the Lester John and Lynne Dewar Lloyd Distinguished Professor of Bioengineering in 2005. He also served as the Chair Professor in Systems Nanobiology at the ETH Zürich from 2006 to 2007. He became Arnold and Barbara Silverman Distinguished Professor at Berkeley in 2010 and was reappointed again 2015. He was the founding director of the Biomedical Institute for Global Healthcare Research & Technology (BIGHEART) and served as Associate President (International Research and Innovation) and Tan Chin Tuan Centennial Professor at the National University of Singapore from 2016 to 2018. He also founded the Institute of Quantum Biophysics at Sungkyunkwan University in Korea in 2018. He became a Professor of Medicine at Harvard Medical School, Harvard University, and Brigham and Women's Hospital in 2020. He is a Fellow of the Royal Society of Chemistry and the American Institute of Medical and Biological Engineering. His work at the interface of biological, physical, and engineering sciences for medicine has been recognized by many honors including the IEEE William J. Morlock Award, NSF Career Award, Fulbright Scholar Award, and the HoAm Prize. Lee has over 350 peer-reviewed publications and over 60 international patents filed. He has trained more than 79 PhD students and postdoctoral fellows in last seventeen years. They have distinguished their careers in research, teaching, consulting, and industry: 33 of them became faculty members in major universities and 9 of them formed startup companies, and others joined in industry or research institutes. His current research interests are quantum biological electron tunneling in living organisms, integrated molecular diagnostic systems for the early detection of cancer and neurodegenerative diseases, in vitro neurogenesis, and organoids on chip.